Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50017877
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187877((S)-1-{2-[3-(3-fluoro-phenylsulfanyl)-biphenyl-4-y...)
Affinity DataIC50:  59nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187875(2-(methyl(2-(2-(phenylthio)phenoxy)ethyl)amino)ace...)
Affinity DataIC50:  160nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187888((S)-1-{2-[3-(3-fluoro-phenylsulfanyl)-4'-methoxy-b...)
Affinity DataIC50:  160nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187869((S)-1-{2-[3-(3-fluoro-phenylsulfanyl)-3'-methoxy-b...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187882((S)-1-(2-(2-(3-chlorophenylthio)phenoxy)ethyl)pyrr...)
Affinity DataIC50:  380nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187874((S)-1-(2-(4-chloro-2-(3-fluorophenylthio)phenoxy)e...)
Affinity DataIC50:  400nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187872((2S)-1-(2-(2-(3-fluorophenylthio)-4-(thiophen-3-yl...)
Affinity DataIC50:  520nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187890((S)-1-(2-(5-chloro-2-(3-fluorophenylthio)phenoxy)e...)
Affinity DataIC50:  600nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187889((S)-1-{2-[4-(3-fluoro-phenylsulfanyl)-biphenyl-3-y...)
Affinity DataIC50:  950nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187868((S)-1-(2-(3-chloro-2-(3-fluorophenylthio)phenoxy)e...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187881((S)-1-{2-[4'-chloro-3-(3-fluoro-phenylsulfanyl)-bi...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187886(2-((2-(2-(3-chlorophenylthio)phenoxy)ethyl)(methyl...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187873(2-((2-(2-(3-fluorophenylthio)phenoxy)ethyl)(methyl...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187879(2-((2-(2-(3-chlorophenylthio)phenoxy)ethyl)(ethyl)...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187871(2-((2-(2-(4-chlorophenylthio)phenoxy)ethyl)(methyl...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187863((S)-2-((1-(2-(3-fluorophenylthio)phenoxy)propan-2-...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187866(2-((2-(2-(4-tert-butylphenylthio)phenoxy)ethyl)(me...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187864(2-((1-(2-(3-fluorophenylthio)phenoxy)butan-2-yl)(m...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187870((R)-2-((1-(2-(3-fluorophenylthio)phenoxy)propan-2-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187883(2-((2-(2-(4-fluorophenylthio)phenoxy)ethyl)(methyl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187885(2-((1-(2-(3-fluorophenylthio)phenoxy)-3-methylbuta...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187884((S)-1-(2-(2-chloro-6-(3-fluorophenylthio)phenoxy)e...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187878((R)-1-(2-(2-(3-chlorophenylthio)phenoxy)ethyl)pyrr...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187867(2-((2-(2-(3-chlorophenylthio)phenoxy)ethyl)(methyl...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187865(2-((2-(2-(4-methoxyphenylthio)phenoxy)ethyl)(methy...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187876(2-(methyl(2-(2-(p-tolylthio)phenoxy)ethyl)amino)ac...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187887(2-((2-(2-(4-acetamidophenylthio)phenoxy)ethyl)(met...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50187880(2-((2-(2-(3-chlorophenylthio)phenoxy)ethyl)(ethyl)...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1b transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed