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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dopamine D1 and D2 receptor (Homo sapiens (Human)) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem | PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1 | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dopamine D1 and D2 receptor (Homo sapiens (Human)) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1 | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Dopamine receptor D2 using raclopride as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dopamine D1 and D2 receptor (Homo sapiens (Human)) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1 | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dopamine D1 and D2 receptor (Homo sapiens (Human)) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1 | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma (HUMAN) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma (HUMAN) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against sigma receptor using DTG as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma (HUMAN) | BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against sigma receptor using DTG as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma (HUMAN) | BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The compound was tested for binding affinity against sigma receptor using DTG as radioligand | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
