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Found 36 Enz. Inhib. hit(s) with all data for entry = 50017922
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188463(4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50:  4nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3535(4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188464(4-[(3-methylphenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188456(1-(2-chloroethyl)-3-{[4-(3-bromophenyl)amino]quina...)
Affinity DataIC50:  18nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188461(1-(2-chloroethyl)-3-{[4-(3-chlorophenyl)amino]quin...)
Affinity DataIC50:  22nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(4-Anilinoquinazoline deriv. 45 | 4-N-(3-bromopheny...)
Affinity DataIC50:  44nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188468(1-(2-chloroethyl)-1-nitroso-3-{[4-(3-bromophenyl)a...)
Affinity DataIC50:  47nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188466(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-chlorophenyl)...)
Affinity DataIC50:  67nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188459(3-(2-chloroethyl)-1-methyl-1-{[4-(3-chlorophenyl)a...)
Affinity DataIC50:  81nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188462(3-(2-chloroethyl)-1-methyl-1-{[4-(3-bromophenyl)am...)
Affinity DataIC50:  156nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3535(4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diam...)
Affinity DataIC50:  170nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133382(Anilinoquinazoline, 4c | CHEMBL343352 | N*4*-(3-Ch...)
Affinity DataIC50:  200nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188458(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-chlo...)
Affinity DataIC50:  204nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188457(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-brom...)
Affinity DataIC50:  294nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(4-Anilinoquinazoline deriv. 45 | 4-N-(3-bromopheny...)
Affinity DataIC50:  670nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188465(1-(2-chloroethyl)-3-{[4-(3-methylphenyl)amino]quin...)
Affinity DataIC50:  676nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188458(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-chlo...)
Affinity DataIC50:  680nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188463(4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50:  890nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133384(Anilinoquinazoline, 4a | CHEMBL336113 | N*4*-m-Tol...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188460(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-methylphenyl)...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188467(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-meth...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188468(1-(2-chloroethyl)-1-nitroso-3-{[4-(3-bromophenyl)a...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188461(1-(2-chloroethyl)-3-{[4-(3-chlorophenyl)amino]quin...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188455(3-(2-chloroethyl)-1-methyl-1-{[4-(3-methylphenyl)a...)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188456(1-(2-chloroethyl)-3-{[4-(3-bromophenyl)amino]quina...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188464(4-[(3-methylphenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188465(1-(2-chloroethyl)-3-{[4-(3-methylphenyl)amino]quin...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188457(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-brom...)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133382(Anilinoquinazoline, 4c | CHEMBL343352 | N*4*-(3-Ch...)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188466(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-chlorophenyl)...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133384(Anilinoquinazoline, 4a | CHEMBL336113 | N*4*-m-Tol...)
Affinity DataIC50:  6.39E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188467(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-meth...)
Affinity DataIC50:  6.88E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188462(3-(2-chloroethyl)-1-methyl-1-{[4-(3-bromophenyl)am...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188455(3-(2-chloroethyl)-1-methyl-1-{[4-(3-methylphenyl)a...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188460(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-methylphenyl)...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188459(3-(2-chloroethyl)-1-methyl-1-{[4-(3-chlorophenyl)a...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed