Affinity Data by PubMed id=1676425

PubMed code 1676425

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406530 (CHEMBL51541) Show SMILES CC(C)(C)NC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406531 (CHEMBL296826) Show SMILES CCNC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	42.7	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406533 (CHEMBL299537) Show SMILES CCC(C)(C)NC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.59	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406528 (CHEMBL362059) Show SMILES CCCCNC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406535 (CHEMBL50020) Show SMILES CC(C)NC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	28.2	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406527 (CHEMBL423660) Show SMILES CCC(CC)NC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406532 (CHEMBL298859) Show SMILES CC(C)CNC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.25	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406534 (CHEMBL50960) Show SMILES CNC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406529 (CHEMBL51540) Show SMILES CCC(C)NC=Nc1ccc(cc1)-c1c[nH]cn1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a
Research Laboratories of Istituto De Angeli Curated by ChEMBL					Assay Description Histamine H2 receptor antagonism on the right atrium of the guinea pig				J Med Chem 34: 1772-6 (1991) Article DOI: 10.1021/jm00110a004 BindingDB Entry DOI: 10.7270/Q2W95BCR
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%