Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50000596
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataIC50:  0.180nMAssay Description:Ability to inhibit binding of [3H]PRAZ to alpha-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataIC50:  0.450nMAssay Description:Ability to inhibit binding of [3H]PRAZ to alpha-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataIC50:  0.480nMAssay Description:Ability to inhibit binding of [3H]KET to 5-hydroxytryptamine 2 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007567(1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...)
Affinity DataIC50:  0.480nMAssay Description:Ability to inhibit binding of [3H]KET to 5-hydroxytryptamine 2 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataIC50:  0.570nMAssay Description:Ability to inhibit binding of [3H]KET to 5-hydroxytryptamine 2 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007567(1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...)
Affinity DataIC50:  1.20nMAssay Description:Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataIC50:  1.30nMAssay Description:Ability to inhibit binding of [3H]-SPI to dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007567(1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...)
Affinity DataIC50:  1.40nMAssay Description:Ability to inhibit binding of [3H]PRAZ to alpha-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataIC50:  2.20nMAssay Description:Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataIC50:  2.20nMAssay Description:Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataIC50:  2.40nMAssay Description:Ability to inhibit binding of [3H]-SPI to dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007567(1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...)
Affinity DataIC50:  6.60nMAssay Description:Ability to inhibit binding of [3H]-SPI to dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed