Compile Data Set for Download or QSAR
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Found 10 Enz. Inhib. hit(s) with all data for entry = 2184
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17847(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Affinity DataIC50:  1.50E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17849(3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...)
Affinity DataIC50:  2.90E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17850(3-(3-phenylpropanamido)-N-(1,3-thiazol-2-yl)pyridi...)
Affinity DataIC50:  3.50E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17851(3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...)
Affinity DataIC50:  6.40E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17847(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Affinity DataIC50: >3.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17850(3-(3-phenylpropanamido)-N-(1,3-thiazol-2-yl)pyridi...)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17849(3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17852(3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17852(3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM17851(3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...)
Affinity DataIC50: >1.00E+6nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed