Affinity Data by PubMed id=1720175

PubMed code 1720175

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50002692 ((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50004152 ((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...) Show SMILES Cc1c(Sc2ccccc2)n(COCCO)c(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells.				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50008017 (1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-phenylselany...) Show SMILES Cc1c([Se]c2ccccc2)n(COCCO)c(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50008019 (5-Chloro-1-(2-hydroxy-ethoxymethyl)-6-phenylselany...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50008008 (5-Fluoro-1-(2-hydroxy-ethoxymethyl)-6-phenylselany...) Show SMILES OCCOCn1c([Se]c2ccccc2)c(F)c(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50008012 (5-Bromo-1-(2-hydroxy-ethoxymethyl)-6-phenylselanyl...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50008010 (1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-phenylselany...) Show SMILES Cc1c([Se]c2ccccc2)n(COCCO)c(=S)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50008016 (1-(2-Hydroxy-ethoxymethyl)-6-phenylselanyl-1H-pyri...) Show SMILES OCCOCn1c([Se]c2ccccc2)cc(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells				J Med Chem 34: 3305-9 (1991) Article DOI: 10.1021/jm00115a022 BindingDB Entry DOI: 10.7270/Q2DR2TFF
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%