BindingDB logo
myBDB logout

PubMed code 1732522

Compile data set for download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008081
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-dihydr...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CSC1=S
Show InChI InChI=1S/C11H16N2S2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 51n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50004665
PNG
((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Show SMILES O=C1CCCN1CC#CCN1CCCC1
Show InChI InChI=1S/C12H18N2O/c15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13/h1-2,5-11H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 113n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008077
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-tetrah...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CSC1O
Show InChI InChI=1S/C11H18N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10-11,14H,3-4,6H2,1-2H3/t8-,10+,11?/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 285n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008064
PNG
((S)-3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-ox...)
Show SMILES CCN1[C@@H](Cc2cncn2C)COC1=O
Show InChI InChI=1S/C10H15N3O2/c1-3-13-9(6-15-10(13)14)4-8-5-11-7-12(8)2/h5,7,9H,3-4,6H2,1-2H3/t9-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 288n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008070
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-dihydr...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)CSC1=O
Show InChI InChI=1S/C11H16N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 435n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008079
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-tetrah...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)CSC1O
Show InChI InChI=1S/C11H18N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10-11,14H,3-4,6H2,1-2H3/t8-,10-,11?/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 695n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008078
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-dihydr...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CSC1=O
Show InChI InChI=1S/C11H16N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 775n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008072
PNG
((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O
Show InChI InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
n/an/a 960n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008071
PNG
(5-methylfurmethide | CHEMBL92387 | Trimethyl-(5-me...)
Show SMILES Cc1ccc(C[N+](C)(C)C)o1
Show InChI InChI=1S/C9H16NO/c1-8-5-6-9(11-8)7-10(2,3)4/h5-6H,7H2,1-4H3/q+1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 1.41E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM46858
PNG
(1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...)
Show SMILES COC(=O)C1=CCCN(C)C1
Show InChI InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.74E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008080
PNG
(5-(4-Ethyl-tetrahydro-furan-3-ylmethyl)-1-methyl-1...)
Show SMILES CC[C@@H]1COC[C@@H]1Cc1cncn1C
Show InChI InChI=1S/C11H18N2O/c1-3-9-6-14-7-10(9)4-11-5-12-8-13(11)2/h5,8-10H,3-4,6-7H2,1-2H3/t9-,10+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008075
PNG
((+)-isopilocarpine | (3R,4R)-3-ethyl-4-[(1-methyl-...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)COC1=O
Show InChI InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008068
PNG
(CHEMBL327819 | Dimethyl-(2-methyl-[1,3]dioxolan-4-...)
Show SMILES CC1OCC(CN(C)C)O1
Show InChI InChI=1S/C7H15NO2/c1-6-9-5-7(10-6)4-8(2)3/h6-7H,4-5H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008074
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-pyrrol...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)CNC1=O
Show InChI InChI=1S/C11H17N3O/c1-3-10-8(5-13-11(10)15)4-9-6-12-7-14(9)2/h6-8,10H,3-5H2,1-2H3,(H,13,15)/t8-,10-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 5.15E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50006243
PNG
(((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...)
Show SMILES C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O
Show InChI InChI=1S/C9H20NO2/c1-7-9(11)5-8(12-7)6-10(2,3)4/h7-9,11H,5-6H2,1-4H3/q+1/t7-,8-,9+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 5.68E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008067
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-pyrrol...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CNC1=O
Show InChI InChI=1S/C11H17N3O/c1-3-10-8(5-13-11(10)15)4-9-6-12-7-14(9)2/h6-8,10H,3-5H2,1-2H3,(H,13,15)/t8-,10+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 9.95E+3n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008073
PNG
(4-(3-Methyl-3H-imidazol-4-ylmethyl)-dihydro-furan-...)
Show SMILES Cn1cncc1C[C@H]1COC(=O)C1
Show InChI InChI=1S/C9H12N2O2/c1-11-6-10-4-8(11)2-7-3-9(12)13-5-7/h4,6-7H,2-3,5H2,1H3/t7-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008069
PNG
(3-Ethyl-1-methyl-4-(3-methyl-3H-imidazol-4-ylmethy...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CN(C)C1=O
Show InChI InChI=1S/C12H19N3O/c1-4-11-9(7-14(2)12(11)16)5-10-6-13-8-15(10)3/h6,8-9,11H,4-5,7H2,1-3H3/t9-,11+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008076
PNG
(3-Ethyl-1-methyl-4-(3-methyl-3H-imidazol-4-ylmethy...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)CN(C)C1=O
Show InChI InChI=1S/C12H19N3O/c1-4-11-9(7-14(2)12(11)16)5-10-6-13-8-15(10)3/h6,8-9,11H,4-5,7H2,1-3H3/t9-,11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.02E+4n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50004656
PNG
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Show SMILES C[N+](C)(C)CCOC(N)=O
Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PubMed
n/an/a 1.19E+4n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50008065
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-tetrah...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1O
Show InChI InChI=1S/C11H18N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10-11,14H,3-4,6H2,1-2H3/t8-,10-,11?/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Compound was tested for its ability to displace [3H]-pirenzepine (pir) from M1 Muscarinic receptor in rat cortical tissue


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008074
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-pyrrol...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)CNC1=O
Show InChI InChI=1S/C11H17N3O/c1-3-10-8(5-13-11(10)15)4-9-6-12-7-14(9)2/h6-8,10H,3-5H2,1-2H3,(H,13,15)/t8-,10-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a>1.00E+5n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008081
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-dihydr...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CSC1=S
Show InChI InChI=1S/C11H16N2S2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/an/a 631n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008078
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-dihydr...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CSC1=O
Show InChI InChI=1S/C11H16N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/an/a 5.01E+3n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008070
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-dihydr...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)CSC1=O
Show InChI InChI=1S/C11H16N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/an/a 3.16E+3n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008072
PNG
((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O
Show InChI InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
n/an/an/a 1.00E+4n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008079
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-tetrah...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)CSC1O
Show InChI InChI=1S/C11H18N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10-11,14H,3-4,6H2,1-2H3/t8-,10-,11?/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 3.98E+3n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008065
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-tetrah...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1O
Show InChI InChI=1S/C11H18N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10-11,14H,3-4,6H2,1-2H3/t8-,10-,11?/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 398n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008077
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-tetrah...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CSC1O
Show InChI InChI=1S/C11H18N2OS/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10-11,14H,3-4,6H2,1-2H3/t8-,10+,11?/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 2.51E+3n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50008067
PNG
(3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-pyrrol...)
Show SMILES CC[C@@H]1[C@@H](Cc2cncn2C)CNC1=O
Show InChI InChI=1S/C11H17N3O/c1-3-10-8(5-13-11(10)15)4-9-6-12-7-14(9)2/h6-8,10H,3-5H2,1-2H3,(H,13,15)/t8-,10+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/an/a>1.00E+5n/an/an/an/an/a



Sandoz Pharma Ltd.

Curated by ChEMBL


Assay Description
Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%