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PubMed code 17341062

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-binding cassette sub-family G member 2


(Homo sapiens (Human))
BDBM50370874
PNG
(CHEMBL221371)
Show SMILES COC1Oc2c(O)cccc2-c2c1oc1cc(OC)cc(O)c1c2=O
Show InChI InChI=1S/C18H14O7/c1-22-8-6-11(20)14-12(7-8)24-17-13(15(14)21)9-4-3-5-10(19)16(9)25-18(17)23-2/h3-7,18-20H,1-2H3
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



UMR 5086 CNRS/Universit£ Lyon 1

Curated by ChEMBL


Assay Description
Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation


J Med Chem 50: 1933-8 (2007)


Article DOI: 10.1021/jm061450q
BindingDB Entry DOI: 10.7270/Q21V5FRP
More data for this
Ligand-Target Pair
ATP-binding cassette sub-family G member 2


(Homo sapiens (Human))
BDBM50370873
PNG
(CHEMBL222265)
Show SMILES COC1Oc2c(O)cccc2-c2c1oc1cc(OC)c(C)c(O)c1c2=O
Show InChI InChI=1S/C19H16O7/c1-8-11(23-2)7-12-14(15(8)21)16(22)13-9-5-4-6-10(20)17(9)26-19(24-3)18(13)25-12/h4-7,19-21H,1-3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



UMR 5086 CNRS/Universit£ Lyon 1

Curated by ChEMBL


Assay Description
Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation


J Med Chem 50: 1933-8 (2007)


Article DOI: 10.1021/jm061450q
BindingDB Entry DOI: 10.7270/Q21V5FRP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%