Compile Data Set for Download or QSAR
maximum 50k data
Found 52 Enz. Inhib. hit(s) with all data for entry = 50019803
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207882(4'-(2,4-dioxo-1-phenyl-3-m-tolyl-1,3,8-triaza-spir...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207875(4'-[3-(3-methoxy-phenyl)-2,4-dioxo-1-phenyl-1,3,8-...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207867(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(4-m...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207891(5-chloro-4'-(2,4-dioxo-1-phenyl-1,3,8-triaza-spiro...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207885(5-{4-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207864(4'-[1-cyclohexyl-3-(3-methoxy-phenyl)-2,4-dioxo-1,...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207884(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(5-m...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207886(4'-[1-cyclohexylmethyl-3-(3-methoxy-phenyl)-2,4-di...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207874(3-({4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2...)
Affinity DataKi:  19nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207873(4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-d...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207876(8-[4-(6-amino-pyridin-3-yl)-benzyl]-1-(2-fluoro-be...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207871(1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-n...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207890(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyri...)
Affinity DataKi:  44nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207898(4'-(2,4-dioxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-...)
Affinity DataKi:  45nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207872(1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-(...)
Affinity DataKi:  50nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207878(4'-[1-cyclopropylmethyl-3-(3-methoxy-phenyl)-2,4-d...)
Affinity DataKi:  84nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207895(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyri...)
Affinity DataKi:  89nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207887(8-(3'-acetyl-biphenyl-4-ylmethyl)-1-(2-fluoro-benz...)
Affinity DataKi:  92nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207903(4'-[1-cyclopropyl-3-(3-methoxy-phenyl)-2,4-dioxo-1...)
Affinity DataKi:  100nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207896(1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-p...)
Affinity DataKi:  115nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207897(3-benzyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-be...)
Affinity DataKi:  150nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207905(CHEMBL389811 | N-{4'-[1-(2-fluoro-benzyl)-3-(3-met...)
Affinity DataKi:  150nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207883(4'-[3-(3-methoxy-phenyl)-1-methyl-2,4-dioxo-1,3,8-...)
Affinity DataKi:  180nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207877(3-butyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-ben...)
Affinity DataKi:  200nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207888(4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-d...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207865(8-[4-(4-chloro-pyridin-3-yl)-benzyl]-1-(2-fluoro-b...)
Affinity DataKi:  230nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207869(4'-[3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-sp...)
Affinity DataKi:  280nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207881(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(2-m...)
Affinity DataKi:  300nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207893(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(6-m...)
Affinity DataKi:  315nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207900(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyri...)
Affinity DataKi:  330nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207866(1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-(...)
Affinity DataKi:  340nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207868(3-cyclohexyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-y...)
Affinity DataKi:  340nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207902(1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-p...)
Affinity DataKi:  400nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207899(1-(2-fluoro-benzyl)-8-(3'-methoxy-biphenyl-4-ylmet...)
Affinity DataKi:  620nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207870(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(6-m...)
Affinity DataKi:  640nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207889(3-ethyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-ben...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207879(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyrr...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207892(1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-1,3...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207904(1-(2-fluoro-benzyl)-8-(3'-hydroxy-biphenyl-4-ylmet...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207901(CHEMBL412007 | N-{4'-[1-(2-fluoro-benzyl)-3-(3-met...)
Affinity DataKi:  8.00E+3nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207880(8-biphenyl-4-ylmethyl-1-(2-fluoro-benzyl)-3-(3-met...)
Affinity DataKi:  9.30E+3nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207894(4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-d...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207886(4'-[1-cyclohexylmethyl-3-(3-methoxy-phenyl)-2,4-di...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells by MCH-stimulated [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207872(1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-(...)
Affinity DataIC50:  35nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207890(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyri...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207895(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyri...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207867(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(4-m...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207884(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(5-m...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207885(5-{4-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207898(4'-(2,4-dioxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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