Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 2036
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16281(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-fluoro-6-meth...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16274(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-fluoro-4-oxo-...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16273(2-({2-[(3R)-3-aminopiperidin-1-yl]-5-fluoro-4-oxo-...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16275(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-chloro-4-oxo-...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16279(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-bromo-4-oxo-3...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16280(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-methoxy-4-oxo...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16285(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)
Affinity DataIC50: <10nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16272(2-({2-[(3R)-3-aminopiperidin-1-yl]-4-oxo-3,4-dihyd...)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16278(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,8-dichloro-4-...)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16276(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-chloro-4-oxo-...)
Affinity DataIC50:  15nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16284(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-fluoro-7-(mor...)
Affinity DataIC50:  18nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16282(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,7-dimethoxy-4...)
Affinity DataIC50:  19nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16277(2-({2-[(3R)-3-aminopiperidin-1-yl]-8-chloro-4-oxo-...)
Affinity DataIC50:  29nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16283(2-({2-[(3R)-3-aminopiperidin-1-yl]-8-methoxy-4-oxo...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16275(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-chloro-4-oxo-...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16284(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-fluoro-7-(mor...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16280(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-methoxy-4-oxo...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16285(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16276(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-chloro-4-oxo-...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16277(2-({2-[(3R)-3-aminopiperidin-1-yl]-8-chloro-4-oxo-...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16278(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,8-dichloro-4-...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16279(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-bromo-4-oxo-3...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16272(2-({2-[(3R)-3-aminopiperidin-1-yl]-4-oxo-3,4-dihyd...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16281(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-fluoro-6-meth...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16282(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,7-dimethoxy-4...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16274(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-fluoro-4-oxo-...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16273(2-({2-[(3R)-3-aminopiperidin-1-yl]-5-fluoro-4-oxo-...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

LigandPNGBDBM16283(2-({2-[(3R)-3-aminopiperidin-1-yl]-8-methoxy-4-oxo...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed