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PubMed code 17553678

Compile data set for download or QSAR
Found 97 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214903
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(3-phenoxypropyl)amino...)
Show SMILES CCC(Oc1cccc(CCN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-2-25(27(31)32)34-23-13-8-10-21(20-23)16-18-30(17-9-19-33-22-11-4-3-5-12-22)28-29-24-14-6-7-15-26(24)35-28/h3-8,10-15,20,25H,2,9,16-19H2,1H3,(H,31,32)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214912
PNG
(2-(3-(((3-phenoxypropyl)(5-(trifluoromethyl)benzo[...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(ccc3o2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C28H27F3N2O5/c1-2-24(26(34)35)37-22-11-6-8-19(16-22)18-33(14-7-15-36-21-9-4-3-5-10-21)27-32-23-17-20(28(29,30)31)12-13-25(23)38-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,34,35)
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n/an/an/an/a 23n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214910
PNG
(2-(3-(3-(benzo[d]oxazol-2-yl(2-phenoxyethyl)amino)...)
Show SMILES CC(C)(Oc1cccc(CCCN(CCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-28(2,26(31)32)35-23-14-8-10-21(20-23)11-9-17-30(18-19-33-22-12-4-3-5-13-22)27-29-24-15-6-7-16-25(24)34-27/h3-8,10,12-16,20H,9,11,17-19H2,1-2H3,(H,31,32)
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n/an/an/an/a 100n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214913
PNG
(2-(3-(((5-hydroxybenzo[d]oxazol-2-yl)(3-phenoxypro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(O)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-29(14-7-15-33-21-9-4-3-5-10-21)27-28-23-17-20(30)12-13-25(23)35-27/h3-6,8-13,16-17,24,30H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214896
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)ami...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)/t24-/m0/s1
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n/an/an/an/a 870n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214895
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C26H26N2O5/c1-19(25(29)30)32-22-12-7-9-20(17-22)18-28(15-8-16-31-21-10-3-2-4-11-21)26-27-23-13-5-6-14-24(23)33-26/h2-7,9-14,17,19H,8,15-16,18H2,1H3,(H,29,30)
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n/an/an/an/a 10n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214917
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3,4-difluorophenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)c(F)c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H26F2N2O5/c1-2-24(26(32)33)35-20-8-5-7-18(15-20)17-31(27-30-23-9-3-4-10-25(23)36-27)13-6-14-34-19-11-12-21(28)22(29)16-19/h3-5,7-12,15-16,24H,2,6,13-14,17H2,1H3,(H,32,33)
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n/an/an/an/a 1.30E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214886
PNG
(2-(3-(((5-methylbenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(C)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-3-25(27(31)32)34-23-12-7-9-21(18-23)19-30(15-8-16-33-22-10-5-4-6-11-22)28-29-24-17-20(2)13-14-26(24)35-28/h4-7,9-14,17-18,25H,3,8,15-16,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 100n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214916
PNG
(2-(3-(((3-(benzo[d][1,3]dioxol-5-yloxy)propyl)(ben...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc3OCOc3c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H28N2O7/c1-2-23(27(31)32)36-21-8-5-7-19(15-21)17-30(28-29-22-9-3-4-10-24(22)37-28)13-6-14-33-20-11-12-25-26(16-20)35-18-34-25/h3-5,7-12,15-16,23H,2,6,13-14,17-18H2,1H3,(H,31,32)
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n/an/an/an/a 1.80E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214900
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(2-phenoxyethyl)amino)...)
Show SMILES CC(C)(Oc1cccc(CCN(CCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-27(2,25(30)31)34-22-12-8-9-20(19-22)15-16-29(17-18-32-21-10-4-3-5-11-21)26-28-23-13-6-7-14-24(23)33-26/h3-14,19H,15-18H2,1-2H3,(H,30,31)
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n/an/an/an/a 1.10E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214902
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-hydroxyphenoxy)pro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(O)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-29(27-28-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(30)12-14-21/h3-5,7-14,17,24,30H,2,6,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.40E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214905
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)ami...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)/t24-/m1/s1
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n/an/an/an/a 1.61E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214903
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(3-phenoxypropyl)amino...)
Show SMILES CCC(Oc1cccc(CCN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-2-25(27(31)32)34-23-13-8-10-21(20-23)16-18-30(17-9-19-33-22-11-4-3-5-12-22)28-29-24-14-6-7-15-26(24)35-28/h3-8,10-15,20,25H,2,9,16-19H2,1H3,(H,31,32)
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n/an/an/an/a 50n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214902
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-hydroxyphenoxy)pro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(O)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-29(27-28-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(30)12-14-21/h3-5,7-14,17,24,30H,2,6,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214905
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)ami...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)/t24-/m1/s1
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n/an/an/an/a 2n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214915
PNG
(2-(3-(((7-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cccc(F)c3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-21-12-6-9-19(17-21)18-30(15-8-16-33-20-10-4-3-5-11-20)27-29-23-14-7-13-22(28)25(23)35-27/h3-7,9-14,17,24H,2,8,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 8.00E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214916
PNG
(2-(3-(((3-(benzo[d][1,3]dioxol-5-yloxy)propyl)(ben...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc3OCOc3c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H28N2O7/c1-2-23(27(31)32)36-21-8-5-7-19(15-21)17-30(28-29-22-9-3-4-10-24(22)37-28)13-6-14-33-20-11-12-25-26(16-20)35-18-34-25/h3-5,7-12,15-16,23H,2,6,13-14,17-18H2,1H3,(H,31,32)
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n/an/an/an/a 1.70E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214894
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)
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n/an/an/an/a 2.00E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214890
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)/t24-/m1/s1
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n/an/an/an/a 940n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214917
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3,4-difluorophenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)c(F)c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H26F2N2O5/c1-2-24(26(32)33)35-20-8-5-7-18(15-20)17-31(27-30-23-9-3-4-10-25(23)36-27)13-6-14-34-19-11-12-21(28)22(29)16-19/h3-5,7-12,15-16,24H,2,6,13-14,17H2,1H3,(H,32,33)
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n/an/an/an/a 2n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214914
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2C)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-25(28(32)33)35-23-10-7-9-22(18-23)19-31(29-30-24-11-5-6-12-27(24)36-29)15-8-16-34-26-14-13-20(2)17-21(26)3/h5-7,9-14,17-18,25H,4,8,15-16,19H2,1-3H3,(H,32,33)
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n/an/an/an/a 1n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214891
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)c(C)c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-26(28(32)33)35-24-10-7-9-22(18-24)19-31(29-30-25-11-5-6-12-27(25)36-29)15-8-16-34-23-14-13-20(2)21(3)17-23/h5-7,9-14,17-18,26H,4,8,15-16,19H2,1-3H3,(H,32,33)
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n/an/an/an/a 750n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214915
PNG
(2-(3-(((7-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cccc(F)c3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-21-12-6-9-19(17-21)18-30(15-8-16-33-20-10-4-3-5-11-20)27-29-23-14-7-13-22(28)25(23)35-27/h3-7,9-14,17,24H,2,8,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 530n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214884
PNG
(2-(3-(((6-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccc(F)cc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-30(14-7-15-33-21-9-4-3-5-10-21)27-29-23-13-12-20(28)17-25(23)35-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.10E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214887
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)prop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 8n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214888
PNG
(2-(3-(((4-hydroxybenzo[d]oxazol-2-yl)(3-phenoxypro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3c(O)cccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-23(26(31)32)34-21-12-6-9-19(17-21)18-29(15-8-16-33-20-10-4-3-5-11-20)27-28-25-22(30)13-7-14-24(25)35-27/h3-7,9-14,17,23,30H,2,8,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 2.00E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214889
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(3-phenoxypropyl)amino...)
Show SMILES CC(Oc1cccc(CCN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-20(26(30)31)33-23-12-7-9-21(19-23)15-17-29(16-8-18-32-22-10-3-2-4-11-22)27-28-24-13-5-6-14-25(24)34-27/h2-7,9-14,19-20H,8,15-18H2,1H3,(H,30,31)
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n/an/an/an/a 10n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214892
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-difluorophenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)cc2F)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H26F2N2O5/c1-2-23(26(32)33)35-20-8-5-7-18(15-20)17-31(27-30-22-9-3-4-10-25(22)36-27)13-6-14-34-24-12-11-19(28)16-21(24)29/h3-5,7-12,15-16,23H,2,6,13-14,17H2,1H3,(H,32,33)
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n/an/an/an/a 11n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214897
PNG
(2-(3-{[[1,3]dioxolo[4',5':4,5]benzo[1,2-d]oxazol-6...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc4OCOc4cc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H28N2O7/c1-2-23(27(31)32)36-21-11-6-8-19(14-21)17-30(12-7-13-33-20-9-4-3-5-10-20)28-29-22-15-25-26(35-18-34-25)16-24(22)37-28/h3-6,8-11,14-16,23H,2,7,12-13,17-18H2,1H3,(H,31,32)
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n/an/an/an/a 1.10E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214887
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)prop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214904
PNG
(2-(3-(((5-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(F)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-30(14-7-15-33-21-9-4-3-5-10-21)27-29-23-17-20(28)12-13-25(23)35-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.00E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214908
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CC(C)(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-27(2,25(30)31)34-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)26-28-23-14-6-7-15-24(23)33-26/h3-8,10-15,18H,9,16-17,19H2,1-2H3,(H,30,31)
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n/an/an/an/a 1.40E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214887
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)prop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214892
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-difluorophenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)cc2F)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H26F2N2O5/c1-2-23(26(32)33)35-20-8-5-7-18(15-20)17-31(27-30-22-9-3-4-10-25(22)36-27)13-6-14-34-24-12-11-19(28)16-21(24)29/h3-5,7-12,15-16,23H,2,6,13-14,17H2,1H3,(H,32,33)
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n/an/an/an/a 2.10E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214901
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)/t24-/m0/s1
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n/an/an/an/a 1.19E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214908
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CC(C)(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-27(2,25(30)31)34-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)26-28-23-14-6-7-15-24(23)33-26/h3-8,10-15,18H,9,16-17,19H2,1-2H3,(H,30,31)
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n/an/an/an/a 5.00E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214910
PNG
(2-(3-(3-(benzo[d]oxazol-2-yl(2-phenoxyethyl)amino)...)
Show SMILES CC(C)(Oc1cccc(CCCN(CCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-28(2,26(31)32)35-23-14-8-10-21(20-23)11-9-17-30(18-19-33-22-12-4-3-5-13-22)27-29-24-15-6-7-16-25(24)34-27/h3-8,10,12-16,20H,9,11,17-19H2,1-2H3,(H,31,32)
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n/an/an/an/a 800n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214889
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(3-phenoxypropyl)amino...)
Show SMILES CC(Oc1cccc(CCN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-20(26(30)31)33-23-12-7-9-21(19-23)15-17-29(16-8-18-32-22-10-3-2-4-11-22)27-28-24-13-5-6-14-25(24)34-27/h2-7,9-14,19-20H,8,15-18H2,1H3,(H,30,31)
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n/an/an/an/a 1.80E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214915
PNG
(2-(3-(((7-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cccc(F)c3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-21-12-6-9-19(17-21)18-30(15-8-16-33-20-10-4-3-5-11-20)27-29-23-14-7-13-22(28)25(23)35-27/h3-7,9-14,17,24H,2,8,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 2n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214913
PNG
(2-(3-(((5-hydroxybenzo[d]oxazol-2-yl)(3-phenoxypro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(O)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-29(14-7-15-33-21-9-4-3-5-10-21)27-28-23-17-20(30)12-13-25(23)35-27/h3-6,8-13,16-17,24,30H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 140n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214912
PNG
(2-(3-(((3-phenoxypropyl)(5-(trifluoromethyl)benzo[...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(ccc3o2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C28H27F3N2O5/c1-2-24(26(34)35)37-22-11-6-8-19(16-22)18-33(14-7-15-36-21-9-4-3-5-10-21)27-32-23-17-20(28(29,30)31)12-13-25(23)38-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,34,35)
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n/an/an/an/a 400n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214885
PNG
(2-(3-((benzo[d]oxazol-2-yl(2-phenoxyethyl)amino)me...)
Show SMILES CC(C)(Oc1cccc(CN(CCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C26H26N2O5/c1-26(2,24(29)30)33-21-12-8-9-19(17-21)18-28(15-16-31-20-10-4-3-5-11-20)25-27-22-13-6-7-14-23(22)32-25/h3-14,17H,15-16,18H2,1-2H3,(H,29,30)
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n/an/an/an/a 2.10E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214904
PNG
(2-(3-(((5-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(F)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-30(14-7-15-33-21-9-4-3-5-10-21)27-29-23-17-20(28)12-13-25(23)35-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.10E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214895
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C26H26N2O5/c1-19(25(29)30)32-22-12-7-9-20(17-22)18-28(15-8-16-31-21-10-3-2-4-11-21)26-27-23-13-5-6-14-24(23)33-26/h2-7,9-14,17,19H,8,15-16,18H2,1H3,(H,29,30)
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n/an/an/an/a 1.20E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214917
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3,4-difluorophenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)c(F)c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H26F2N2O5/c1-2-24(26(32)33)35-20-8-5-7-18(15-20)17-31(27-30-23-9-3-4-10-25(23)36-27)13-6-14-34-19-11-12-21(28)22(29)16-19/h3-5,7-12,15-16,24H,2,6,13-14,17H2,1H3,(H,32,33)
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n/an/an/an/a 1.80E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214909
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3-nitrophenoxy)propy...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2cccc(c2)[N+]([O-])=O)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27N3O7/c1-2-24(26(31)32)36-22-11-5-8-19(16-22)18-29(27-28-23-12-3-4-13-25(23)37-27)14-7-15-35-21-10-6-9-20(17-21)30(33)34/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214909
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3-nitrophenoxy)propy...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2cccc(c2)[N+]([O-])=O)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27N3O7/c1-2-24(26(31)32)36-22-11-5-8-19(16-22)18-29(27-28-23-12-3-4-13-25(23)37-27)14-7-15-35-21-10-6-9-20(17-21)30(33)34/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.40E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214891
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)c(C)c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-26(28(32)33)35-24-10-7-9-22(18-24)19-31(29-30-25-11-5-6-12-27(25)36-29)15-8-16-34-23-14-13-20(2)21(3)17-23/h5-7,9-14,17-18,26H,4,8,15-16,19H2,1-3H3,(H,32,33)
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n/an/an/an/a 830n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214897
PNG
(2-(3-{[[1,3]dioxolo[4',5':4,5]benzo[1,2-d]oxazol-6...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc4OCOc4cc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H28N2O7/c1-2-23(27(31)32)36-21-11-6-8-19(14-21)17-30(12-7-13-33-20-9-4-3-5-10-20)28-29-22-15-25-26(35-18-34-25)16-24(22)37-28/h3-6,8-11,14-16,23H,2,7,12-13,17-18H2,1H3,(H,31,32)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214898
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m0/s1
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n/an/an/an/a 1.80E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214902
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-hydroxyphenoxy)pro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(O)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-29(27-28-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(30)12-14-21/h3-5,7-14,17,24,30H,2,6,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 260n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214913
PNG
(2-(3-(((5-hydroxybenzo[d]oxazol-2-yl)(3-phenoxypro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(O)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-29(14-7-15-33-21-9-4-3-5-10-21)27-28-23-17-20(30)12-13-25(23)35-27/h3-6,8-13,16-17,24,30H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 180n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214898
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m0/s1
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n/an/an/an/a 1.31E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214906
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)pro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214893
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(p-tolyloxy)propyl)am...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-3-25(27(31)32)34-23-9-6-8-21(18-23)19-30(28-29-24-10-4-5-11-26(24)35-28)16-7-17-33-22-14-12-20(2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 210n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214894
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)
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n/an/an/an/a 9n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214896
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)ami...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)/t24-/m0/s1
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n/an/an/an/a 130n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214895
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C26H26N2O5/c1-19(25(29)30)32-22-12-7-9-20(17-22)18-28(15-8-16-31-21-10-3-2-4-11-21)26-27-23-13-5-6-14-24(23)33-26/h2-7,9-14,17,19H,8,15-16,18H2,1H3,(H,29,30)
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n/an/an/an/a 2.70E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214901
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)/t24-/m0/s1
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n/an/an/an/a 1.57E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214903
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(3-phenoxypropyl)amino...)
Show SMILES CCC(Oc1cccc(CCN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-2-25(27(31)32)34-23-13-8-10-21(20-23)16-18-30(17-9-19-33-22-11-4-3-5-12-22)28-29-24-14-6-7-15-26(24)35-28/h3-8,10-15,20,25H,2,9,16-19H2,1H3,(H,31,32)
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n/an/an/an/a 1.40E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214910
PNG
(2-(3-(3-(benzo[d]oxazol-2-yl(2-phenoxyethyl)amino)...)
Show SMILES CC(C)(Oc1cccc(CCCN(CCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-28(2,26(31)32)35-23-14-8-10-21(20-23)11-9-17-30(18-19-33-22-12-4-3-5-13-22)27-29-24-15-6-7-16-25(24)34-27/h3-8,10,12-16,20H,9,11,17-19H2,1-2H3,(H,31,32)
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n/an/an/an/a 100n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214886
PNG
(2-(3-(((5-methylbenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(C)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-3-25(27(31)32)34-23-12-7-9-21(18-23)19-30(15-8-16-33-22-10-5-4-6-11-22)28-29-24-17-20(2)13-14-26(24)35-28/h4-7,9-14,17-18,25H,3,8,15-16,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 5.00E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214888
PNG
(2-(3-(((4-hydroxybenzo[d]oxazol-2-yl)(3-phenoxypro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3c(O)cccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-23(26(31)32)34-21-12-6-9-19(17-21)18-29(15-8-16-33-20-10-4-3-5-11-20)27-28-25-22(30)13-7-14-24(25)35-27/h3-7,9-14,17,23,30H,2,8,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 160n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214908
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CC(C)(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-27(2,25(30)31)34-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)26-28-23-14-6-7-15-24(23)33-26/h3-8,10-15,18H,9,16-17,19H2,1-2H3,(H,30,31)
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n/an/an/an/a 190n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214898
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m0/s1
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n/an/an/an/a 10n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214906
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)pro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 1.70E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214894
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214899
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1
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n/an/an/an/a 1.10E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214888
PNG
(2-(3-(((4-hydroxybenzo[d]oxazol-2-yl)(3-phenoxypro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3c(O)cccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O6/c1-2-23(26(31)32)34-21-12-6-9-19(17-21)18-29(15-8-16-33-20-10-4-3-5-11-20)27-28-25-22(30)13-7-14-24(25)35-27/h3-7,9-14,17,23,30H,2,8,15-16,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.90E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214891
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)c(C)c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-26(28(32)33)35-24-10-7-9-22(18-24)19-31(29-30-25-11-5-6-12-27(25)36-29)15-8-16-34-23-14-13-20(2)21(3)17-23/h5-7,9-14,17-18,26H,4,8,15-16,19H2,1-3H3,(H,32,33)
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n/an/an/an/a 1n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214914
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2C)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-25(28(32)33)35-23-10-7-9-22(18-23)19-31(29-30-24-11-5-6-12-27(24)36-29)15-8-16-34-26-14-13-20(2)17-21(26)3/h5-7,9-14,17-18,25H,4,8,15-16,19H2,1-3H3,(H,32,33)
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n/an/an/an/a 130n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214896
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)ami...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)/t24-/m0/s1
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n/an/an/an/a 1.66E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214886
PNG
(2-(3-(((5-methylbenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(C)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-3-25(27(31)32)34-23-12-7-9-21(18-23)19-30(15-8-16-33-22-10-5-4-6-11-22)28-29-24-17-20(2)13-14-26(24)35-28/h4-7,9-14,17-18,25H,3,8,15-16,19H2,1-2H3,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214890
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)/t24-/m1/s1
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n/an/an/an/a 3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214899
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1
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n/an/an/an/a 1.58E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214884
PNG
(2-(3-(((6-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccc(F)cc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-30(14-7-15-33-21-9-4-3-5-10-21)27-29-23-13-12-20(28)17-25(23)35-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 1.90E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214884
PNG
(2-(3-(((6-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccc(F)cc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-30(14-7-15-33-21-9-4-3-5-10-21)27-29-23-13-12-20(28)17-25(23)35-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 5n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214907
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)m...)
Show SMILES OC(=O)COc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1
Show InChI InChI=1S/C25H24N2O5/c28-24(29)18-31-21-11-6-8-19(16-21)17-27(14-7-15-30-20-9-2-1-3-10-20)25-26-22-12-4-5-13-23(22)32-25/h1-6,8-13,16H,7,14-15,17-18H2,(H,28,29)
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n/an/an/an/a 1.20E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214909
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(3-nitrophenoxy)propy...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2cccc(c2)[N+]([O-])=O)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27N3O7/c1-2-24(26(31)32)36-22-11-5-8-19(16-22)18-29(27-28-23-12-3-4-13-25(23)37-27)14-7-15-35-21-10-6-9-20(17-21)30(33)34/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 24n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214914
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2C)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-25(28(32)33)35-23-10-7-9-22(18-23)19-31(29-30-24-11-5-6-12-27(24)36-29)15-8-16-34-26-14-13-20(2)17-21(26)3/h5-7,9-14,17-18,25H,4,8,15-16,19H2,1-3H3,(H,32,33)
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n/an/an/an/a 110n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214905
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)ami...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-2-24(26(30)31)33-22-13-8-10-20(18-22)19-29(16-9-17-32-21-11-4-3-5-12-21)27-28-23-14-6-7-15-25(23)34-27/h3-8,10-15,18,24H,2,9,16-17,19H2,1H3,(H,30,31)/t24-/m1/s1
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n/an/an/an/a 910n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214904
PNG
(2-(3-(((5-fluorobenzo[d]oxazol-2-yl)(3-phenoxyprop...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(F)ccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-11-6-8-19(16-22)18-30(14-7-15-33-21-9-4-3-5-10-21)27-29-23-17-20(28)12-13-25(23)35-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,31,32)
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n/an/an/an/a 3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214897
PNG
(2-(3-{[[1,3]dioxolo[4',5':4,5]benzo[1,2-d]oxazol-6...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc4OCOc4cc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H28N2O7/c1-2-23(27(31)32)36-21-11-6-8-19(14-21)17-30(12-7-13-33-20-9-4-3-5-10-20)28-29-22-15-25-26(35-18-34-25)16-24(22)37-28/h3-6,8-11,14-16,23H,2,7,12-13,17-18H2,1H3,(H,31,32)
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n/an/an/an/a 5n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214890
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)/t24-/m1/s1
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n/an/an/an/a 1.19E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214885
PNG
(2-(3-((benzo[d]oxazol-2-yl(2-phenoxyethyl)amino)me...)
Show SMILES CC(C)(Oc1cccc(CN(CCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C26H26N2O5/c1-26(2,24(29)30)33-21-12-8-9-19(17-21)18-28(15-16-31-20-10-4-3-5-11-20)25-27-22-13-6-7-14-23(22)32-25/h3-14,17H,15-16,18H2,1-2H3,(H,29,30)
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n/an/an/an/a 630n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214889
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(3-phenoxypropyl)amino...)
Show SMILES CC(Oc1cccc(CCN(CCCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-20(26(30)31)33-23-12-7-9-21(19-23)15-17-29(16-8-18-32-22-10-3-2-4-11-22)27-28-24-13-5-6-14-25(24)34-27/h2-7,9-14,19-20H,8,15-18H2,1H3,(H,30,31)
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n/an/an/an/a 2.30E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214893
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(p-tolyloxy)propyl)am...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-3-25(27(31)32)34-23-9-6-8-21(18-23)19-30(28-29-24-10-4-5-11-26(24)35-28)16-7-17-33-22-14-12-20(2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 1n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214906
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)pro...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 1n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214893
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(p-tolyloxy)propyl)am...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O5/c1-3-25(27(31)32)34-23-9-6-8-21(18-23)19-30(28-29-24-10-4-5-11-26(24)35-28)16-7-17-33-22-14-12-20(2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 120n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214901
PNG
((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...)
Show SMILES CC[C@H](Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H27FN2O5/c1-2-24(26(31)32)34-22-8-5-7-19(17-22)18-30(27-29-23-9-3-4-10-25(23)35-27)15-6-16-33-21-13-11-20(28)12-14-21/h3-5,7-14,17,24H,2,6,15-16,18H2,1H3,(H,31,32)/t24-/m0/s1
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n/an/an/an/a 20n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214911
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-(methoxysulfonyl)p...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(cc2)S(=O)(=O)OC)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O8S/c1-3-25(27(31)32)37-22-9-6-8-20(18-22)19-30(28-29-24-10-4-5-11-26(24)38-28)16-7-17-36-21-12-14-23(15-13-21)39(33,34)35-2/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214892
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-difluorophenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(F)cc2F)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H26F2N2O5/c1-2-23(26(32)33)35-20-8-5-7-18(15-20)17-31(27-30-22-9-3-4-10-25(22)36-27)13-6-14-34-24-12-11-19(28)16-21(24)29/h3-5,7-12,15-16,23H,2,6,13-14,17H2,1H3,(H,32,33)
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n/an/an/an/a 6.50E+3n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214899
PNG
((R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy...)
Show SMILES CC[C@@H](Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1
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n/an/an/an/a 1n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214911
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(4-(methoxysulfonyl)p...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(cc2)S(=O)(=O)OC)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H30N2O8S/c1-3-25(27(31)32)37-22-9-6-8-20(18-22)19-30(28-29-24-10-4-5-11-26(24)38-28)16-7-17-36-21-12-14-23(15-13-21)39(33,34)35-2/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)
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n/an/an/an/a 120n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214900
PNG
(2-(3-(2-(benzo[d]oxazol-2-yl(2-phenoxyethyl)amino)...)
Show SMILES CC(C)(Oc1cccc(CCN(CCOc2ccccc2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C27H28N2O5/c1-27(2,25(30)31)34-22-12-8-9-20(19-22)15-16-29(17-18-32-21-10-4-3-5-11-21)26-28-23-13-6-7-14-24(23)33-26/h3-14,19H,15-18H2,1-2H3,(H,30,31)
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n/an/an/an/a 30n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214916
PNG
(2-(3-(((3-(benzo[d][1,3]dioxol-5-yloxy)propyl)(ben...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc3OCOc3c2)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C28H28N2O7/c1-2-23(27(31)32)36-21-8-5-7-19(15-21)17-30(28-29-22-9-3-4-10-24(22)37-28)13-6-14-33-20-11-12-25-26(16-20)35-18-34-25/h3-5,7-12,15-16,23H,2,6,13-14,17-18H2,1H3,(H,31,32)
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n/an/an/an/a 7n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214912
PNG
(2-(3-(((3-phenoxypropyl)(5-(trifluoromethyl)benzo[...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(ccc3o2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C28H27F3N2O5/c1-2-24(26(34)35)37-22-11-6-8-19(16-22)18-33(14-7-15-36-21-9-4-3-5-10-21)27-32-23-17-20(28(29,30)31)12-13-25(23)38-27/h3-6,8-13,16-17,24H,2,7,14-15,18H2,1H3,(H,34,35)
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n/an/an/an/a 160n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.066
BindingDB Entry DOI: 10.7270/Q2J67GM5
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%