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PubMed code 17576063

Compile data set for download or QSAR
Found 69 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30273
PNG
(carboline analog, 85)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NC1CCN(C)CC1
Show InChI InChI=1S/C23H26N6O3S/c1-12-10-24-22(32)19-18(12)15-9-13(3-4-16(15)26-19)20(30)28-23-27-17(11-33-23)21(31)25-14-5-7-29(2)8-6-14/h3-4,9,11-12,14,26H,5-8,10H2,1-2H3,(H,24,32)(H,25,31)(H,27,28,30)
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n/an/a 10n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30265
PNG
(carboline analog, 77)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NCCN
Show InChI InChI=1S/C19H20N6O3S/c1-9-7-22-18(28)15-14(9)11-6-10(2-3-12(11)23-15)16(26)25-19-24-13(8-29-19)17(27)21-5-4-20/h2-3,6,8-9,23H,4-5,7,20H2,1H3,(H,21,27)(H,22,28)(H,24,25,26)
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n/an/a 17n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30268
PNG
(carboline analog, 80)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NCCC(N)=O
Show InChI InChI=1S/C20H20N6O4S/c1-9-7-23-19(30)16-15(9)11-6-10(2-3-12(11)24-16)17(28)26-20-25-13(8-31-20)18(29)22-5-4-14(21)27/h2-3,6,8-9,24H,4-5,7H2,1H3,(H2,21,27)(H,22,29)(H,23,30)(H,25,26,28)
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n/an/a 21n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30269
PNG
(carboline analog, 81)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NCCO
Show InChI InChI=1S/C19H19N5O4S/c1-9-7-21-18(28)15-14(9)11-6-10(2-3-12(11)22-15)16(26)24-19-23-13(8-29-19)17(27)20-4-5-25/h2-3,6,8-9,22,25H,4-5,7H2,1H3,(H,20,27)(H,21,28)(H,23,24,26)
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n/an/a 31n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30264
PNG
(carboline analog, 76)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NCCN(C)C
Show InChI InChI=1S/C21H24N6O3S/c1-11-9-23-20(30)17-16(11)13-8-12(4-5-14(13)24-17)18(28)26-21-25-15(10-31-21)19(29)22-6-7-27(2)3/h4-5,8,10-11,24H,6-7,9H2,1-3H3,(H,22,29)(H,23,30)(H,25,26,28)
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n/an/a 34n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30266
PNG
(carboline analog, 78)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NCCCN(C)C
Show InChI InChI=1S/C22H26N6O3S/c1-12-10-24-21(31)18-17(12)14-9-13(5-6-15(14)25-18)19(29)27-22-26-16(11-32-22)20(30)23-7-4-8-28(2)3/h5-6,9,11-12,25H,4,7-8,10H2,1-3H3,(H,23,30)(H,24,31)(H,26,27,29)
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n/an/a 35n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30271
PNG
(carboline analog, 83)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C23H25N5O3S/c1-12-10-24-22(31)19-18(12)15-9-13(7-8-16(15)26-19)20(29)28-23-27-17(11-32-23)21(30)25-14-5-3-2-4-6-14/h7-9,11-12,14,26H,2-6,10H2,1H3,(H,24,31)(H,25,30)(H,27,28,29)
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n/an/a 44n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30270
PNG
(carboline analog, 82)
Show SMILES CCCNC(=O)c1csc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)n1
Show InChI InChI=1S/C20H21N5O3S/c1-3-6-21-18(27)14-9-29-20(24-14)25-17(26)11-4-5-13-12(7-11)15-10(2)8-22-19(28)16(15)23-13/h4-5,7,9-10,23H,3,6,8H2,1-2H3,(H,21,27)(H,22,28)(H,24,25,26)
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n/an/a 45n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30262
PNG
(carboline analog, 74)
Show SMILES CNC(=O)c1csc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)n1
Show InChI InChI=1S/C18H17N5O3S/c1-8-6-20-17(26)14-13(8)10-5-9(3-4-11(10)21-14)15(24)23-18-22-12(7-27-18)16(25)19-2/h3-5,7-8,21H,6H2,1-2H3,(H,19,25)(H,20,26)(H,22,23,24)
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n/an/a 72n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30259
PNG
(carboline analog, 71)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(N)=O
Show InChI InChI=1S/C17H15N5O3S/c1-7-5-19-16(25)13-12(7)9-4-8(2-3-10(9)20-13)15(24)22-17-21-11(6-26-17)14(18)23/h2-4,6-7,20H,5H2,1H3,(H2,18,23)(H,19,25)(H,21,22,24)
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n/an/a 83n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30261
PNG
(carboline analog, 73)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncc(s1)C(N)=O
Show InChI InChI=1S/C17H15N5O3S/c1-7-5-19-16(25)13-12(7)9-4-8(2-3-10(9)21-13)15(24)22-17-20-6-11(26-17)14(18)23/h2-4,6-7,21H,5H2,1H3,(H2,18,23)(H,19,25)(H,20,22,24)
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n/an/a 120n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30267
PNG
(carboline analog, 79)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NCC(N)=O
Show InChI InChI=1S/C19H18N6O4S/c1-8-5-21-18(29)15-14(8)10-4-9(2-3-11(10)23-15)16(27)25-19-24-12(7-30-19)17(28)22-6-13(20)26/h2-4,7-8,23H,5-6H2,1H3,(H2,20,26)(H,21,29)(H,22,28)(H,24,25,27)
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n/an/a 124n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30272
PNG
(carboline analog, 84)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)N1CCC(CC1)N(C)C
Show InChI InChI=1S/C24H28N6O3S/c1-13-11-25-22(32)20-19(13)16-10-14(4-5-17(16)26-20)21(31)28-24-27-18(12-34-24)23(33)30-8-6-15(7-9-30)29(2)3/h4-5,10,12-13,15,26H,6-9,11H2,1-3H3,(H,25,32)(H,27,28,31)
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n/an/a 250n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30263
PNG
(carboline analog, 75)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)N(C)C
Show InChI InChI=1S/C19H19N5O3S/c1-9-7-20-17(26)15-14(9)11-6-10(4-5-12(11)21-15)16(25)23-19-22-13(8-28-19)18(27)24(2)3/h4-6,8-9,21H,7H2,1-3H3,(H,20,26)(H,22,23,25)
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n/an/a 333n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30228
PNG
(carboline analog, 40)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cnccn1
Show InChI InChI=1S/C17H15N5O2/c1-9-7-20-17(24)15-14(9)11-6-10(2-3-12(11)21-15)16(23)22-13-8-18-4-5-19-13/h2-6,8-9,21H,7H2,1H3,(H,20,24)(H,19,22,23)
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n/an/a 440n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30275
PNG
(carboline analog, 87)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncc(s1)C(=O)NCCCN(C)C
Show InChI InChI=1S/C22H26N6O3S/c1-12-10-24-21(31)18-17(12)14-9-13(5-6-15(14)26-18)19(29)27-22-25-11-16(32-22)20(30)23-7-4-8-28(2)3/h5-6,9,11-12,26H,4,7-8,10H2,1-3H3,(H,23,30)(H,24,31)(H,25,27,29)
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n/an/a 480n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30223
PNG
(carboline analog, 35)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccnc1
Show InChI InChI=1S/C18H16N4O2/c1-10-8-20-18(24)16-15(10)13-7-11(4-5-14(13)22-16)17(23)21-12-3-2-6-19-9-12/h2-7,9-10,22H,8H2,1H3,(H,20,24)(H,21,23)
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n/an/a 520n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30257
PNG
(carboline analog, 69)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(nc1)C(N)=O
Show InChI InChI=1S/C19H17N5O3/c1-9-7-22-19(27)16-15(9)12-6-10(2-4-13(12)24-16)18(26)23-11-3-5-14(17(20)25)21-8-11/h2-6,8-9,24H,7H2,1H3,(H2,20,25)(H,22,27)(H,23,26)
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n/an/a 620n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30255
PNG
(carboline analog, 67)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(cc1)C(N)=O
Show InChI InChI=1S/C20H18N4O3/c1-10-9-22-20(27)17-16(10)14-8-12(4-7-15(14)24-17)19(26)23-13-5-2-11(3-6-13)18(21)25/h2-8,10,24H,9H2,1H3,(H2,21,25)(H,22,27)(H,23,26)
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PubMed
n/an/a 620n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30258
PNG
(carboline analog, 70)
Show SMILES COC(=O)c1csc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)n1
Show InChI InChI=1S/C18H16N4O4S/c1-8-6-19-16(24)14-13(8)10-5-9(3-4-11(10)20-14)15(23)22-18-21-12(7-27-18)17(25)26-2/h3-5,7-8,20H,6H2,1-2H3,(H,19,24)(H,21,22,23)
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n/an/a 750n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30256
PNG
(carboline analog, 68)
Show SMILES COC(=O)c1ccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)cn1
Show InChI InChI=1S/C20H18N4O4/c1-10-8-22-19(26)17-16(10)13-7-11(3-5-14(13)24-17)18(25)23-12-4-6-15(21-9-12)20(27)28-2/h3-7,9-10,24H,8H2,1-2H3,(H,22,26)(H,23,25)
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PubMed
n/an/a 760n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30224
PNG
(carboline analog, 36)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccncc1
Show InChI InChI=1S/C18H16N4O2/c1-10-9-20-18(24)16-15(10)13-8-11(2-3-14(13)22-16)17(23)21-12-4-6-19-7-5-12/h2-8,10,22H,9H2,1H3,(H,20,24)(H,19,21,23)
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PubMed
n/an/a 760n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30260
PNG
(carboline analog, 72)
Show SMILES COC(=O)c1cnc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)s1
Show InChI InChI=1S/C18H16N4O4S/c1-8-6-19-16(24)14-13(8)10-5-9(3-4-11(10)21-14)15(23)22-18-20-7-12(27-18)17(25)26-2/h3-5,7-8,21H,6H2,1-2H3,(H,19,24)(H,20,22,23)
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n/an/a 770n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30242
PNG
(carboline analog, 54)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(c1)C#N
Show InChI InChI=1S/C20H16N4O2/c1-11-10-22-20(26)18-17(11)15-8-13(5-6-16(15)24-18)19(25)23-14-4-2-3-12(7-14)9-21/h2-8,11,24H,10H2,1H3,(H,22,26)(H,23,25)
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n/an/a 770n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30225
PNG
(carboline analog, 37)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nccs1
Show InChI InChI=1S/C16H14N4O2S/c1-8-7-18-15(22)13-12(8)10-6-9(2-3-11(10)19-13)14(21)20-16-17-4-5-23-16/h2-6,8,19H,7H2,1H3,(H,18,22)(H,17,20,21)
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PubMed
n/an/a 820n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30253
PNG
(carboline analog, 65)
Show SMILES COC(=O)c1ccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)cc1
Show InChI InChI=1S/C21H19N3O4/c1-11-10-22-20(26)18-17(11)15-9-13(5-8-16(15)24-18)19(25)23-14-6-3-12(4-7-14)21(27)28-2/h3-9,11,24H,10H2,1-2H3,(H,22,26)(H,23,25)
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PubMed
n/an/a 930n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30240
PNG
(carboline analog, 52)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C19H16ClN3O2/c1-10-9-21-19(25)17-16(10)14-7-11(5-6-15(14)23-17)18(24)22-13-4-2-3-12(20)8-13/h2-8,10,23H,9H2,1H3,(H,21,25)(H,22,24)
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PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30274
PNG
(carboline analog, 86)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncc(s1)C(=O)NCCN(C)C
Show InChI InChI=1S/C21H24N6O3S/c1-11-9-23-20(30)17-16(11)13-8-12(4-5-14(13)25-17)18(28)26-21-24-10-15(31-21)19(29)22-6-7-27(2)3/h4-5,8,10-11,25H,6-7,9H2,1-3H3,(H,22,29)(H,23,30)(H,24,26,28)
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PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30227
PNG
(carboline analog, 39)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccncn1
Show InChI InChI=1S/C17H15N5O2/c1-9-7-19-17(24)15-14(9)11-6-10(2-3-12(11)21-15)16(23)22-13-4-5-18-8-20-13/h2-6,8-9,21H,7H2,1H3,(H,19,24)(H,18,20,22,23)
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PubMed
n/an/a 1.50E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30226
PNG
(carboline analog, 38)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccon1
Show InChI InChI=1S/C16H14N4O3/c1-8-7-17-16(22)14-13(8)10-6-9(2-3-11(10)18-14)15(21)19-12-4-5-23-20-12/h2-6,8,18H,7H2,1H3,(H,17,22)(H,19,20,21)
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n/an/a 1.50E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30230
PNG
(carboline analog, 42)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc2ccccc2s1
Show InChI InChI=1S/C20H16N4O2S/c1-10-9-21-19(26)17-16(10)12-8-11(6-7-13(12)22-17)18(25)24-20-23-14-4-2-3-5-15(14)27-20/h2-8,10,22H,9H2,1H3,(H,21,26)(H,23,24,25)
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PubMed
n/an/a 1.50E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30252
PNG
(carboline analog, 64)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(cc1)C#N
Show InChI InChI=1S/C20H16N4O2/c1-11-10-22-20(26)18-17(11)15-8-13(4-7-16(15)24-18)19(25)23-14-5-2-12(9-21)3-6-14/h2-8,11,24H,10H2,1H3,(H,22,26)(H,23,25)
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PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30239
PNG
(carboline analog, 51)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(F)c1
Show InChI InChI=1S/C19H16FN3O2/c1-10-9-21-19(25)17-16(10)14-7-11(5-6-15(14)23-17)18(24)22-13-4-2-3-12(20)8-13/h2-8,10,23H,9H2,1H3,(H,21,25)(H,22,24)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30250
PNG
(carboline analog, 62)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H16ClN3O2/c1-10-9-21-19(25)17-16(10)14-8-11(2-7-15(14)23-17)18(24)22-13-5-3-12(20)4-6-13/h2-8,10,23H,9H2,1H3,(H,21,25)(H,22,24)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30254
PNG
(carboline analog, 66)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C21H20N4O3/c1-11-10-22-21(28)19-18(11)16-9-13(3-8-17(16)25-19)20(27)24-15-6-4-14(5-7-15)23-12(2)26/h3-9,11,25H,10H2,1-2H3,(H,22,28)(H,23,26)(H,24,27)
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n/an/a 1.80E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30241
PNG
(carboline analog, 53)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(Br)c1
Show InChI InChI=1S/C19H16BrN3O2/c1-10-9-21-19(25)17-16(10)14-7-11(5-6-15(14)23-17)18(24)22-13-4-2-3-12(20)8-13/h2-8,10,23H,9H2,1H3,(H,21,25)(H,22,24)
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n/an/a 2.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30245
PNG
(carboline analog, 57)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(c1)C(N)=O
Show InChI InChI=1S/C20H18N4O3/c1-10-9-22-20(27)17-16(10)14-8-12(5-6-15(14)24-17)19(26)23-13-4-2-3-11(7-13)18(21)25/h2-8,10,24H,9H2,1H3,(H2,21,25)(H,22,27)(H,23,26)
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n/an/a 2.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30220
PNG
(carboline analog, 32)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H17N3O2/c1-11-10-20-19(24)17-16(11)14-9-12(7-8-15(14)22-17)18(23)21-13-5-3-2-4-6-13/h2-9,11,22H,10H2,1H3,(H,20,24)(H,21,23)
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n/an/a 2.90E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30235
PNG
(carboline analog, 47)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1C(N)=O
Show InChI InChI=1S/C20H18N4O3/c1-10-9-22-20(27)17-16(10)13-8-11(6-7-15(13)23-17)19(26)24-14-5-3-2-4-12(14)18(21)25/h2-8,10,23H,9H2,1H3,(H2,21,25)(H,22,27)(H,24,26)
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n/an/a 3.00E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30246
PNG
(carboline analog, 58)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C20H19N3O2/c1-11-3-6-14(7-4-11)22-19(24)13-5-8-16-15(9-13)17-12(2)10-21-20(25)18(17)23-16/h3-9,12,23H,10H2,1-2H3,(H,21,25)(H,22,24)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30249
PNG
(carboline analog, 61)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C19H16FN3O2/c1-10-9-21-19(25)17-16(10)14-8-11(2-7-15(14)23-17)18(24)22-13-5-3-12(20)4-6-13/h2-8,10,23H,9H2,1H3,(H,21,25)(H,22,24)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30236
PNG
(carboline analog, 48)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C20H19N3O2/c1-11-4-3-5-14(8-11)22-19(24)13-6-7-16-15(9-13)17-12(2)10-21-20(25)18(17)23-16/h3-9,12,23H,10H2,1-2H3,(H,21,25)(H,22,24)
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n/an/a 3.40E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30244
PNG
(carboline analog, 56)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(NC(C)=O)c1
Show InChI InChI=1S/C21H20N4O3/c1-11-10-22-21(28)19-18(11)16-8-13(6-7-17(16)25-19)20(27)24-15-5-3-4-14(9-15)23-12(2)26/h3-9,11,25H,10H2,1-2H3,(H,22,28)(H,23,26)(H,24,27)
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n/an/a 4.40E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30212
PNG
(carboline analog, 17)
Show SMILES COc1ccc2[nH]c3c(C(C)CNC3=O)c2c1
Show InChI InChI=1S/C13H14N2O2/c1-7-6-14-13(16)12-11(7)9-5-8(17-2)3-4-10(9)15-12/h3-5,7,15H,6H2,1-2H3,(H,14,16)
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n/an/a 4.50E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30215
PNG
(carboline analog, 27)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(N)=O
Show InChI InChI=1S/C13H13N3O2/c1-6-5-15-13(18)11-10(6)8-4-7(12(14)17)2-3-9(8)16-11/h2-4,6,16H,5H2,1H3,(H2,14,17)(H,15,18)
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n/an/a 5.40E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30251
PNG
(carboline analog, 63)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C19H16BrN3O2/c1-10-9-21-19(25)17-16(10)14-8-11(2-7-15(14)23-17)18(24)22-13-5-3-12(20)4-6-13/h2-8,10,23H,9H2,1H3,(H,21,25)(H,22,24)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30243
PNG
(carboline analog, 55)
Show SMILES CCOC(=O)c1cccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)c1
Show InChI InChI=1S/C22H21N3O4/c1-3-29-22(28)14-5-4-6-15(9-14)24-20(26)13-7-8-17-16(10-13)18-12(2)11-23-21(27)19(18)25-17/h4-10,12,25H,3,11H2,1-2H3,(H,23,27)(H,24,26)
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n/an/a 7.40E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30247
PNG
(carboline analog, 59)
Show SMILES CC(C)c1ccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)cc1
Show InChI InChI=1S/C22H23N3O2/c1-12(2)14-4-7-16(8-5-14)24-21(26)15-6-9-18-17(10-15)19-13(3)11-23-22(27)20(19)25-18/h4-10,12-13,25H,11H2,1-3H3,(H,23,27)(H,24,26)
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n/an/a 7.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30232
PNG
(carboline analog, 44)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1F
Show InChI InChI=1S/C19H16FN3O2/c1-10-9-21-19(25)17-16(10)12-8-11(6-7-14(12)22-17)18(24)23-15-5-3-2-4-13(15)20/h2-8,10,22H,9H2,1H3,(H,21,25)(H,23,24)
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n/an/a 9.70E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30233
PNG
(carboline analog, 45)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1Br
Show InChI InChI=1S/C19H16BrN3O2/c1-10-9-21-19(25)17-16(10)12-8-11(6-7-14(12)22-17)18(24)23-15-5-3-2-4-13(15)20/h2-8,10,22H,9H2,1H3,(H,21,25)(H,23,24)
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n/an/a>1.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30234
PNG
(carboline analog, 46)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1C#N
Show InChI InChI=1S/C20H16N4O2/c1-11-10-22-20(26)18-17(11)14-8-12(6-7-16(14)23-18)19(25)24-15-5-3-2-4-13(15)9-21/h2-8,11,23H,10H2,1H3,(H,22,26)(H,24,25)
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n/an/a>1.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30216
PNG
(carboline analog, 28)
Show SMILES CNC(=O)c1ccc2[nH]c3c(C(C)CNC3=O)c2c1
Show InChI InChI=1S/C14H15N3O2/c1-7-6-16-14(19)12-11(7)9-5-8(13(18)15-2)3-4-10(9)17-12/h3-5,7,17H,6H2,1-2H3,(H,15,18)(H,16,19)
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n/an/a 1.20E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30210
PNG
(carboline analog, 23)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(Br)cc3c12
Show InChI InChI=1S/C12H11BrN2O/c1-6-5-14-12(16)11-10(6)8-4-7(13)2-3-9(8)15-11/h2-4,6,15H,5H2,1H3,(H,14,16)
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n/an/a 1.50E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30238
PNG
(carboline analog, 50)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(c1)C(C)(C)C
Show InChI InChI=1S/C23H25N3O2/c1-13-12-24-22(28)20-19(13)17-10-14(8-9-18(17)26-20)21(27)25-16-7-5-6-15(11-16)23(2,3)4/h5-11,13,26H,12H2,1-4H3,(H,24,28)(H,25,27)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30237
PNG
(carboline analog, 49)
Show SMILES CC(C)c1cccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)c1
Show InChI InChI=1S/C22H23N3O2/c1-12(2)14-5-4-6-16(9-14)24-21(26)15-7-8-18-17(10-15)19-13(3)11-23-22(27)20(19)25-18/h4-10,12-13,25H,11H2,1-3H3,(H,23,27)(H,24,26)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30222
PNG
(carboline analog, 34)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C21H21N3O2/c1-13-12-23-21(26)19-18(13)16-11-15(7-8-17(16)24-19)20(25)22-10-9-14-5-3-2-4-6-14/h2-8,11,13,24H,9-10,12H2,1H3,(H,22,25)(H,23,26)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30219
PNG
(carboline analog, 31)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)N1CCCCC1
Show InChI InChI=1S/C18H21N3O2/c1-11-10-19-17(22)16-15(11)13-9-12(5-6-14(13)20-16)18(23)21-7-3-2-4-8-21/h5-6,9,11,20H,2-4,7-8,10H2,1H3,(H,19,22)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30221
PNG
(carboline analog, 33)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C20H19N3O2/c1-12-10-21-20(25)18-17(12)15-9-14(7-8-16(15)23-18)19(24)22-11-13-5-3-2-4-6-13/h2-9,12,23H,10-11H2,1H3,(H,21,25)(H,22,24)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30248
PNG
(carboline analog, 60)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C23H25N3O2/c1-13-12-24-22(28)20-19(13)17-11-14(5-10-18(17)26-20)21(27)25-16-8-6-15(7-9-16)23(2,3)4/h5-11,13,26H,12H2,1-4H3,(H,24,28)(H,25,27)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30217
PNG
(carboline analog, 29)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)N(C)C
Show InChI InChI=1S/C15H17N3O2/c1-8-7-16-14(19)13-12(8)10-6-9(15(20)18(2)3)4-5-11(10)17-13/h4-6,8,17H,7H2,1-3H3,(H,16,19)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30218
PNG
(carboline analog, 30)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)NC1CCCCC1
Show InChI InChI=1S/C19H23N3O2/c1-11-10-20-19(24)17-16(11)14-9-12(7-8-15(14)22-17)18(23)21-13-5-3-2-4-6-13/h7-9,11,13,22H,2-6,10H2,1H3,(H,20,24)(H,21,23)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30231
PNG
(carboline analog, 43)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1C
Show InChI InChI=1S/C20H19N3O2/c1-11-5-3-4-6-15(11)23-19(24)13-7-8-16-14(9-13)17-12(2)10-21-20(25)18(17)22-16/h3-9,12,22H,10H2,1-2H3,(H,21,25)(H,23,24)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30229
PNG
(carboline analog, 41)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncccn1
Show InChI InChI=1S/C17H15N5O2/c1-9-8-20-16(24)14-13(9)11-7-10(3-4-12(11)21-14)15(23)22-17-18-5-2-6-19-17/h2-7,9,21H,8H2,1H3,(H,20,24)(H,18,19,22,23)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30211
PNG
(carboline analog, 24)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(O)cc3c12
Show InChI InChI=1S/C12H12N2O2/c1-6-5-13-12(16)11-10(6)8-4-7(15)2-3-9(8)14-11/h2-4,6,14-15H,5H2,1H3,(H,13,16)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30208
PNG
(carboline analog, 21)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(C)cc3c12
Show InChI InChI=1S/C13H14N2O/c1-7-3-4-10-9(5-7)11-8(2)6-14-13(16)12(11)15-10/h3-5,8,15H,6H2,1-2H3,(H,14,16)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30207
PNG
(carboline analog, 20)
Show SMILES CC1CNC(=O)c2[nH]c3ccccc3c12
Show InChI InChI=1S/C12H12N2O/c1-7-6-13-12(15)11-10(7)8-4-2-3-5-9(8)14-11/h2-5,7,14H,6H2,1H3,(H,13,15)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30213
PNG
(carboline analog, 25)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(OCc4ccccc4)cc3c12
Show InChI InChI=1S/C19H18N2O2/c1-12-10-20-19(22)18-17(12)15-9-14(7-8-16(15)21-18)23-11-13-5-3-2-4-6-13/h2-9,12,21H,10-11H2,1H3,(H,20,22)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30209
PNG
(carboline analog, 22)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)-c1ccccc1
Show InChI InChI=1S/C18H16N2O/c1-11-10-19-18(21)17-16(11)14-9-13(7-8-15(14)20-17)12-5-3-2-4-6-12/h2-9,11,20H,10H2,1H3,(H,19,21)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30214
PNG
(carboline analog, 26)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(NC(C)=O)cc3c12
Show InChI InChI=1S/C14H15N3O2/c1-7-6-15-14(19)13-12(7)10-5-9(16-8(2)18)3-4-11(10)17-13/h3-5,7,17H,6H2,1-2H3,(H,15,19)(H,16,18)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%