Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50020643
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216027(CHEMBL247183 | N-hydroxy-6-(2-phenylacetamido)benz...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216014(6-(benzamidomethyl)-N-hydroxybenzo[b]thiophene-2-c...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216016((S)-N-hydroxy-6-(2-phenylbutanamido)benzo[b]thioph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216038(CHEMBL247384 | N-hydroxy-6-(2-(4-methoxyphenyl)ace...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216021(6-(2-(4-fluorophenyl)acetamido)-N-hydroxybenzo[b]t...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216032(CHEMBL247184 | N-hydroxy-5-(2-phenylacetamido)benz...)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216019(CHEMBL246783 | N-hydroxy-6-(2-phenylbutanamido)ben...)
Affinity DataIC50:  40nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216031(CHEMBL247784 | N-hydroxy-6-((phenylamino)methyl)be...)
Affinity DataIC50:  45nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216037(6-((benzylamino)methyl)-N-hydroxybenzo[b]thiophene...)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216013(CHEMBL247382 | N-hydroxy-6-(3-phenylpropanamido)be...)
Affinity DataIC50:  55nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216011(6-(benzylamino)-N-hydroxybenzo[b]thiophene-2-carbo...)
Affinity DataIC50:  55nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216036((R)-N-hydroxy-6-(2-phenylbutanamido)benzo[b]thioph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216034(CHEMBL245357 | N-hydroxy-6-(phenethylamino)benzo[b...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216018(CHEMBL394888 | N-hydroxy-6-((2-phenylacetamido)met...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216015(5-(benzylamino)-N-hydroxybenzo[b]thiophene-2-carbo...)
Affinity DataIC50:  75nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216035(CHEMBL245363 | N-hydroxy-6-((phenethylamino)methyl...)
Affinity DataIC50:  128nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216028(5-((benzylamino)methyl)-N-hydroxybenzo[b]thiophene...)
Affinity DataIC50:  145nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216012(CHEMBL245554 | N-hydroxy-5-(phenethylamino)benzo[b...)
Affinity DataIC50:  155nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216026(CHEMBL248382 | N-hydroxy-5-((phenylamino)methyl)be...)
Affinity DataIC50:  175nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216025(CHEMBL391156 | N-hydroxy-5-((phenethylamino)methyl...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216017(6-benzamido-N-hydroxybenzo[b]thiophene-2-carboxami...)
Affinity DataIC50:  205nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216030(6-(benzhydrylamino)-N-hydroxybenzo[b]thiophene-2-c...)
Affinity DataIC50:  285nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216023(CHEMBL245553 | N-hydroxy-5-(phenylamino)benzo[b]th...)
Affinity DataIC50:  600nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216029(CHEMBL246336 | N-hydroxy-6-(phenylamino)benzo[b]th...)
Affinity DataIC50:  615nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216020(CHEMBL246759 | methyl 2-(hydroxycarbamoyl)benzo[b]...)
Affinity DataIC50:  630nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216024(CHEMBL245946 | N-hydroxybenzo[b]thiophene-2-carbox...)
Affinity DataIC50:  670nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216033(CHEMBL394887 | N-hydroxythiophene-2-carboxamide)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216022(CHEMBL246947 | N-hydroxythiophene-3-carboxamide)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015184(BENZHYDROXAMIC ACID | BENZOHYDROXAMATE | CHEMBL163...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099857(ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...)
Affinity DataIC50:  6.25E+5nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed