Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50025358
TargetC-X-C chemokine receptor type 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270276(CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270276(CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...)
Affinity DataKi:  110nMAssay Description:Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataKi:  220nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetC-X-C chemokine receptor type 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataKi:  890nMAssay Description:Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetC-X-C chemokine receptor type 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270277(Benzyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmeth...)
Affinity DataKi:  1.70E+3nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50035719(1-(4-Methyl-benzyl)-1,4,8,11tetraaza-cyclotetradec...)
Affinity DataKi:  2.00E+4nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed