Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50020793
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217604(4-(5-(6-methoxynaphthalen-2-yl)-1-methyl-2-(4-(met...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217605(4-(4-(6-methylnaphthalen-2-yl)-2-(4-(methylsulfiny...)
Affinity DataIC50:  219nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217603(4-(4-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfin...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217610(4-(2-(4-(methylsulfinyl)phenyl)-4-(naphthalen-2-yl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217609(4-(4-(6-bromonaphthalen-2-yl)-2-(4-(methylsulfinyl...)
Affinity DataIC50:  339nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217611(4-(5-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfin...)
Affinity DataIC50:  437nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217612(4-(1-isobutyl-5-(6-methoxynaphthalen-2-yl)-2-(4-(m...)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217608(4-(1-ethyl-5-(6-methoxynaphthalen-2-yl)-2-(4-(meth...)
Affinity DataIC50:  5.37E+3nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217606(4-(2-(4-(methylsulfinyl)phenyl)-4-(6-phenylnaphtha...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217607(4-[2-(4-methanesulfinyl-phenyl)-5-(6-methoxy-napht...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed