Compile Data Set for Download or QSAR
maximum 50k data
Found 68 Enz. Inhib. hit(s) with all data for entry = 50020828
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218071((R)-2-amino-N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophe...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218106(CHEMBL400932 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218066((R)-2-amino-N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophe...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218065(CHEMBL402058 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218068(CHEMBL400934 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218079(3-amino-N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophenyl)...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218100(2-amino-N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophenyl)...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218075(CHEMBL248435 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218101(CHEMBL401465 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218093((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218067(3-amino-N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophenyl)...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218091(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218082(CHEMBL251594 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  17.3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218087(CHEMBL402060 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218070((4-(2-((S)-1-amino-2-methylpropyl)-6-fluorophenyl)...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218080((4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluorometh...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218073(CHEMBL251587 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  47nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218077((S)-2-amino-N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophe...)
Affinity DataKi:  47nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218063(CHEMBL248687 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataKi:  87nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218096((4-(2-((4-aminopiperidin-1-yl)methyl)phenyl)pipera...)
Affinity DataKi:  92nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218081(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  190nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218069((4-(2-((1H-imidazol-1-yl)methyl)phenyl)piperazin-1...)
Affinity DataKi:  220nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218104((4-(2-((2-aminoethylamino)methyl)phenyl)piperazin-...)
Affinity DataKi:  230nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218072((4-(2-((azetidin-3-yl(methyl)amino)methyl)phenyl)p...)
Affinity DataKi:  240nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218095(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  250nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218085(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  270nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218102(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  280nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218108(CHEMBL250797 | [(3S,4R)-4-(4-chloro-phenyl)-1-isop...)
Affinity DataKi:  320nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218099(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  320nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218110(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  360nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218083((4-(2-((1H-1,2,3-triazol-1-yl)methyl)phenyl)pipera...)
Affinity DataKi:  420nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218088(CHEMBL399557 | N-((14S,15R)-2-(4-((3R,4S)-3-(4-chl...)
Affinity DataKi:  450nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218090((4-(2-((1H-pyrazol-1-yl)methyl)phenyl)piperazin-1-...)
Affinity DataKi:  490nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218111(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  510nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218097(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  520nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218074((4-(2-((azetidin-3-ylamino)methyl)phenyl)piperazin...)
Affinity DataKi:  520nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218084(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  550nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218076(CHEMBL400510 | [(3S,4R)-4-(4-chloro-phenyl)-1-isop...)
Affinity DataKi:  580nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218103(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  840nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218109(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  950nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218094(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218092((4-(2-(aminomethyl)phenyl)piperazin-1-yl)((3S,4R)-...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218105(2-(4-((3R,4S)-3-(4-chlorophenyl)-1-isopropylpyrrol...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218086(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218089(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218064((4-(2-((2-aminophenylamino)methyl)phenyl)piperazin...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218078(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218107(CHEMBL250778 | N-((14S,15R)-2-(4-((3R,4S)-3-(4-chl...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218098(2-(4-((3R,4S)-3-(4-chlorophenyl)-1-isopropylpyrrol...)
Affinity DataKi:  4.80E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218063(CHEMBL248687 | N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...)
Affinity DataEC50:  450nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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