Affinity Data by PubMed id=1766006

PubMed code 1766006

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50342601 (CHEMBL1255901 \| Huperzine A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50342601 (CHEMBL1255901 \| Huperzine A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50008685 (1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50008685 (1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50008689 (1-Amino-13-ethylidene-6-aza-tricyclo[7.3.1.02,7]...) Show SMILES C\C=C1/C2CCC[C@]1(N)c1ccc(=O)[nH]c1C2 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50008684 (5-Amino-6-ethylidene-5-methyl-5,6,7,8-tetrahydro-1...) Show SMILES C\C=C1/CCc2[nH]c(=O)ccc2[C@]1(C)N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50008687 (5-Dimethylaminomethyl-1H-pyridin-2-one \| CHEMBL323...) Show SMILES CN(C)Cc1ccc(=O)[nH]c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50008688 (5-Aminomethyl-1H-pyridin-2-one \| CHEMBL323807) Show SMILES NCc1ccc(=O)[nH]c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex				J Med Chem 34: 3399-402 (1992) Article DOI: 10.1021/jm00116a010 BindingDB Entry DOI: 10.7270/Q2TB17HH
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%