BindingDB logo
myBDB logout

PubMed code 17722902

Compile data set for download or QSAR
Found 16 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 7 (mGlu7)


(Rattus norvegicus (Rat))
BDBM50007548
PNG
((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 4.40E+5n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8 (mGlu8)


(Rattus norvegicus (Rat))
BDBM50220011
PNG
(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O
Show InChI InChI=1S/C4H10NO4PS/c5-3(4(6)7)1-2-10(8,9)11/h3H,1-2,5H2,(H,6,7)(H2,8,9,11)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 54n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7 (mGlu7)


(Rattus norvegicus (Rat))
BDBM50220011
PNG
(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O
Show InChI InChI=1S/C4H10NO4PS/c5-3(4(6)7)1-2-10(8,9)11/h3H,1-2,5H2,(H,6,7)(H2,8,9,11)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 1.97E+5n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7 (mGlu7)


(Rattus norvegicus (Rat))
BDBM50220009
PNG
(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Show SMILES N[C@@H](CCP(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO4P/c5-3(4(6)7)1-2-10(8)9/h3,10H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+5n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50220011
PNG
(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O
Show InChI InChI=1S/C4H10NO4PS/c5-3(4(6)7)1-2-10(8,9)11/h3H,1-2,5H2,(H,6,7)(H2,8,9,11)/t3-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 39n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7 (mGlu7)


(Rattus norvegicus (Rat))
BDBM50174527
PNG
((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O
Show InChI InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+5n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8 (mGlu8)


(Rattus norvegicus (Rat))
BDBM50220009
PNG
(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Show SMILES N[C@@H](CCP(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO4P/c5-3(4(6)7)1-2-10(8)9/h3,10H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.72E+3n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50220009
PNG
(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Show SMILES N[C@@H](CCP(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO4P/c5-3(4(6)7)1-2-10(8)9/h3,10H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.05E+3n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50174527
PNG
((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O
Show InChI InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.10E+6n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50007548
PNG
((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 80n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 6 (mGlu6)


(Rattus norvegicus (Rat))
BDBM50174527
PNG
((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O
Show InChI InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+5n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 6 (mGlu6)


(Rattus norvegicus (Rat))
BDBM50220009
PNG
(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Show SMILES N[C@@H](CCP(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO4P/c5-3(4(6)7)1-2-10(8)9/h3,10H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.78E+4n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 6 (mGlu6)


(Rattus norvegicus (Rat))
BDBM50220011
PNG
(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O
Show InChI InChI=1S/C4H10NO4PS/c5-3(4(6)7)1-2-10(8,9)11/h3H,1-2,5H2,(H,6,7)(H2,8,9,11)/t3-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 730n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 6 (mGlu6)


(Rattus norvegicus (Rat))
BDBM50007548
PNG
((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.08E+3n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8 (mGlu8)


(Rattus norvegicus (Rat))
BDBM50174527
PNG
((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O
Show InChI InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.12E+5n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8 (mGlu8)


(Rattus norvegicus (Rat))
BDBM50007548
PNG
((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 128n/an/an/an/a



Université Paris Descartes

Curated by ChEMBL


Assay Description
Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production


J Med Chem 50: 4656-64 (2007)


Article DOI: 10.1021/jm070400y
BindingDB Entry DOI: 10.7270/Q2XP74NQ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%