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PubMed code 17897949

Compile data set for download or QSAR
Found 12 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 2


(Mus musculus)
BDBM50242406
PNG
(CHEMBL448652 | SNEWIQPRLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C67H101N21O19/c1-5-34(4)54(86-60(100)44(26-35-29-76-39-12-7-6-11-37(35)39)83-57(97)42(18-21-53(93)94)78-59(99)45(28-52(71)92)82-55(95)38(68)31-89)63(103)81-43(17-20-51(70)91)64(104)87-23-9-14-48(87)61(101)79-40(13-8-22-75-67(72)73)56(96)84-46(25-33(2)3)65(105)88-24-10-15-49(88)62(102)80-41(16-19-50(69)90)58(98)85-47(66(106)107)27-36-30-74-32-77-36/h6-7,11-12,29-30,32-34,38,40-49,54,76,89H,5,8-10,13-28,31,68H2,1-4H3,(H2,69,90)(H2,70,91)(H2,71,92)(H,74,77)(H,78,99)(H,79,101)(H,80,102)(H,81,103)(H,82,95)(H,83,97)(H,84,96)(H,85,98)(H,86,100)(H,93,94)(H,106,107)(H4,72,73,75)/t34-,38-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,54-/m0/s1
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PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at mouse EphB2 receptor by ELISA


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242413
PNG
(CHEMBL453443 | SNQWILPRLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C68H105N21O17/c1-7-36(6)55(87-61(99)45(27-37-30-77-41-14-9-8-13-39(37)41)83-58(96)43(18-20-52(70)91)79-60(98)46(29-54(72)93)82-56(94)40(69)32-90)64(102)85-48(26-35(4)5)66(104)89-24-11-16-50(89)62(100)80-42(15-10-22-76-68(73)74)57(95)84-47(25-34(2)3)65(103)88-23-12-17-51(88)63(101)81-44(19-21-53(71)92)59(97)86-49(67(105)106)28-38-31-75-33-78-38/h8-9,13-14,30-31,33-36,40,42-51,55,77,90H,7,10-12,15-29,32,69H2,1-6H3,(H2,70,91)(H2,71,92)(H2,72,93)(H,75,78)(H,79,98)(H,80,100)(H,81,101)(H,82,94)(H,83,96)(H,84,95)(H,85,102)(H,86,97)(H,87,99)(H,105,106)(H4,73,74,76)/t36-,40-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,55-/m0/s1
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n/an/an/a>5.00E+4n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242408
PNG
(CHEMBL526907 | SNEWISPRLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C65H98N20O19/c1-5-33(4)52(83-58(97)42(24-34-27-73-38-12-7-6-11-36(34)38)79-55(94)41(17-19-51(90)91)75-57(96)43(26-50(68)89)78-53(92)37(66)29-86)61(100)82-46(30-87)63(102)85-22-10-15-48(85)59(98)76-39(13-8-20-72-65(69)70)54(93)80-44(23-32(2)3)62(101)84-21-9-14-47(84)60(99)77-40(16-18-49(67)88)56(95)81-45(64(103)104)25-35-28-71-31-74-35/h6-7,11-12,27-28,31-33,37,39-48,52,73,86-87H,5,8-10,13-26,29-30,66H2,1-4H3,(H2,67,88)(H2,68,89)(H,71,74)(H,75,96)(H,76,98)(H,77,99)(H,78,92)(H,79,94)(H,80,93)(H,81,95)(H,82,100)(H,83,97)(H,90,91)(H,103,104)(H4,69,70,72)/t33-,37-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,52-/m0/s1
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n/an/an/a 1.10E+4n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242416
PNG
(CHEMBL508295 | TNYLFSPNGPIARAW)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)[C@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
Show InChI InChI=1S/C80H115N21O21/c1-8-41(4)65(77(119)90-43(6)66(108)91-51(21-14-28-86-80(84)85)69(111)89-42(5)67(109)97-57(79(121)122)34-47-37-87-50-20-13-12-19-49(47)50)99-75(117)59-22-15-29-100(59)63(107)38-88-68(110)55(35-61(81)105)95-74(116)60-23-16-30-101(60)78(120)58(39-102)98-72(114)53(32-45-17-10-9-11-18-45)93-70(112)52(31-40(2)3)92-71(113)54(33-46-24-26-48(104)27-25-46)94-73(115)56(36-62(82)106)96-76(118)64(83)44(7)103/h9-13,17-20,24-27,37,40-44,51-60,64-65,87,102-104H,8,14-16,21-23,28-36,38-39,83H2,1-7H3,(H2,81,105)(H2,82,106)(H,88,110)(H,89,111)(H,90,119)(H,91,108)(H,92,113)(H,93,112)(H,94,115)(H,95,116)(H,96,118)(H,97,109)(H,98,114)(H,99,117)(H,121,122)(H4,84,85,86)/t41-,42-,43-,44-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,64-,65-/m0/s1
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n/an/an/a>5.00E+4n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242415
PNG
(CHEMBL504627 | SNQWIGPALPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C61H90N18O17/c1-6-31(4)50(77-56(90)40(22-33-25-67-37-12-8-7-11-35(33)37)74-53(87)38(15-17-46(63)81)71-55(89)41(24-48(65)83)73-52(86)36(62)28-80)59(93)68-27-49(84)78-19-9-13-44(78)57(91)70-32(5)51(85)75-42(21-30(2)3)60(94)79-20-10-14-45(79)58(92)72-39(16-18-47(64)82)54(88)76-43(61(95)96)23-34-26-66-29-69-34/h7-8,11-12,25-26,29-32,36,38-45,50,67,80H,6,9-10,13-24,27-28,62H2,1-5H3,(H2,63,81)(H2,64,82)(H2,65,83)(H,66,69)(H,68,93)(H,70,91)(H,71,89)(H,72,92)(H,73,86)(H,74,87)(H,75,85)(H,76,88)(H,77,90)(H,95,96)/t31-,32-,36-,38-,39-,40-,41-,42-,43-,44-,45-,50-/m0/s1
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n/an/an/a>5.00E+4n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242406
PNG
(CHEMBL448652 | SNEWIQPRLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C67H101N21O19/c1-5-34(4)54(86-60(100)44(26-35-29-76-39-12-7-6-11-37(35)39)83-57(97)42(18-21-53(93)94)78-59(99)45(28-52(71)92)82-55(95)38(68)31-89)63(103)81-43(17-20-51(70)91)64(104)87-23-9-14-48(87)61(101)79-40(13-8-22-75-67(72)73)56(96)84-46(25-33(2)3)65(105)88-24-10-15-49(88)62(102)80-41(16-19-50(69)90)58(98)85-47(66(106)107)27-36-30-74-32-77-36/h6-7,11-12,29-30,32-34,38,40-49,54,76,89H,5,8-10,13-28,31,68H2,1-4H3,(H2,69,90)(H2,70,91)(H2,71,92)(H,74,77)(H,78,99)(H,79,101)(H,80,102)(H,81,103)(H,82,95)(H,83,97)(H,84,96)(H,85,98)(H,86,100)(H,93,94)(H,106,107)(H4,72,73,75)/t34-,38-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,54-/m0/s1
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n/an/an/a 6.00E+3n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242409
PNG
(CHEMBL526325 | SNEWILPRLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C68H104N20O18/c1-7-36(6)55(86-61(99)45(27-37-30-76-41-14-9-8-13-39(37)41)82-58(96)44(19-21-54(92)93)78-60(98)46(29-53(71)91)81-56(94)40(69)32-89)64(102)84-48(26-35(4)5)66(104)88-24-11-16-50(88)62(100)79-42(15-10-22-75-68(72)73)57(95)83-47(25-34(2)3)65(103)87-23-12-17-51(87)63(101)80-43(18-20-52(70)90)59(97)85-49(67(105)106)28-38-31-74-33-77-38/h8-9,13-14,30-31,33-36,40,42-51,55,76,89H,7,10-12,15-29,32,69H2,1-6H3,(H2,70,90)(H2,71,91)(H,74,77)(H,78,98)(H,79,100)(H,80,101)(H,81,94)(H,82,96)(H,83,95)(H,84,102)(H,85,97)(H,86,99)(H,92,93)(H,105,106)(H4,72,73,75)/t36-,40-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,55-/m0/s1
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n/an/an/a 3.00E+3n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242407
PNG
(CHEMBL525059 | SNQWIQPRLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C67H102N22O18/c1-5-34(4)54(87-60(100)44(26-35-29-77-39-12-7-6-11-37(35)39)84-57(97)41(16-19-50(69)91)79-59(99)45(28-53(72)94)83-55(95)38(68)31-90)63(103)82-43(18-21-52(71)93)64(104)88-23-9-14-48(88)61(101)80-40(13-8-22-76-67(73)74)56(96)85-46(25-33(2)3)65(105)89-24-10-15-49(89)62(102)81-42(17-20-51(70)92)58(98)86-47(66(106)107)27-36-30-75-32-78-36/h6-7,11-12,29-30,32-34,38,40-49,54,77,90H,5,8-10,13-28,31,68H2,1-4H3,(H2,69,91)(H2,70,92)(H2,71,93)(H2,72,94)(H,75,78)(H,79,99)(H,80,101)(H,81,102)(H,82,103)(H,83,95)(H,84,97)(H,85,96)(H,86,98)(H,87,100)(H,106,107)(H4,73,74,76)/t34-,38-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,54-/m0/s1
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242412
PNG
(CHEMBL451203 | SNEWIQPHLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C67H96N20O19/c1-5-34(4)55(85-61(99)44(23-35-27-74-40-11-7-6-10-38(35)40)81-57(95)42(16-19-54(92)93)77-60(98)46(26-53(71)91)80-56(94)39(68)30-88)64(102)79-43(15-18-52(70)90)65(103)86-20-8-13-50(86)63(101)82-45(24-36-28-72-31-75-36)59(97)83-47(22-33(2)3)66(104)87-21-9-12-49(87)62(100)78-41(14-17-51(69)89)58(96)84-48(67(105)106)25-37-29-73-32-76-37/h6-7,10-11,27-29,31-34,39,41-50,55,74,88H,5,8-9,12-26,30,68H2,1-4H3,(H2,69,89)(H2,70,90)(H2,71,91)(H,72,75)(H,73,76)(H,77,98)(H,78,100)(H,79,102)(H,80,94)(H,81,95)(H,82,101)(H,83,97)(H,84,96)(H,85,99)(H,92,93)(H,105,106)/t34-,39-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,55-/m0/s1
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242414
PNG
(CHEMBL505364 | SNQWISPRLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C65H99N21O18/c1-5-33(4)52(84-58(97)42(24-34-27-74-38-12-7-6-11-36(34)38)80-55(94)40(16-18-49(67)89)76-57(96)43(26-51(69)91)79-53(92)37(66)29-87)61(100)83-46(30-88)63(102)86-22-10-15-48(86)59(98)77-39(13-8-20-73-65(70)71)54(93)81-44(23-32(2)3)62(101)85-21-9-14-47(85)60(99)78-41(17-19-50(68)90)56(95)82-45(64(103)104)25-35-28-72-31-75-35/h6-7,11-12,27-28,31-33,37,39-48,52,74,87-88H,5,8-10,13-26,29-30,66H2,1-4H3,(H2,67,89)(H2,68,90)(H2,69,91)(H,72,75)(H,76,96)(H,77,98)(H,78,99)(H,79,92)(H,80,94)(H,81,93)(H,82,95)(H,83,100)(H,84,97)(H,103,104)(H4,70,71,73)/t33-,37-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,52-/m0/s1
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n/an/an/a>5.00E+4n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242410
PNG
(CHEMBL508644 | SNEWIQPKLPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C67H101N19O19/c1-5-35(4)55(84-61(98)45(27-36-30-74-40-13-7-6-12-38(36)40)81-58(95)43(19-22-54(91)92)76-60(97)46(29-53(72)90)80-56(93)39(69)32-87)64(101)79-44(18-21-52(71)89)65(102)85-24-10-15-49(85)62(99)77-41(14-8-9-23-68)57(94)82-47(26-34(2)3)66(103)86-25-11-16-50(86)63(100)78-42(17-20-51(70)88)59(96)83-48(67(104)105)28-37-31-73-33-75-37/h6-7,12-13,30-31,33-35,39,41-50,55,74,87H,5,8-11,14-29,32,68-69H2,1-4H3,(H2,70,88)(H2,71,89)(H2,72,90)(H,73,75)(H,76,97)(H,77,99)(H,78,100)(H,79,101)(H,80,93)(H,81,95)(H,82,94)(H,83,96)(H,84,98)(H,91,92)(H,104,105)/t35-,39-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,55-/m0/s1
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n/an/an/a 6.00E+3n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens)
BDBM50242411
PNG
(CHEMBL504700 | SNEWIQPALPQH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C64H94N18O19/c1-6-32(4)52(80-58(94)42(24-34-27-70-38-12-8-7-11-36(34)38)77-55(91)40(17-20-51(87)88)73-57(93)43(26-50(68)86)76-54(90)37(65)29-83)61(97)75-41(16-19-49(67)85)62(98)81-21-9-13-46(81)59(95)72-33(5)53(89)78-44(23-31(2)3)63(99)82-22-10-14-47(82)60(96)74-39(15-18-48(66)84)56(92)79-45(64(100)101)25-35-28-69-30-71-35/h7-8,11-12,27-28,30-33,37,39-47,52,70,83H,6,9-10,13-26,29,65H2,1-5H3,(H2,66,84)(H2,67,85)(H2,68,86)(H,69,71)(H,72,95)(H,73,93)(H,74,96)(H,75,97)(H,76,90)(H,77,91)(H,78,89)(H,79,92)(H,80,94)(H,87,88)(H,100,101)/t32-,33-,37-,39-,40-,41-,42-,43-,44-,45-,46-,47-,52-/m0/s1
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n/an/an/a>5.00E+4n/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human EphB2 receptor by isothermal titration calorimetry


J Biol Chem 282: 36505-13 (2007)


Article DOI: 10.1074/jbc.M706340200
BindingDB Entry DOI: 10.7270/Q29C6X7S
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%