BindingDB logo
myBDB logout

PubMed code 17962026

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(MOUSE)
BDBM50373765
PNG
(CHEMBL271026)
Show SMILES C[C@H]1C2Cc3ccc(O)cc3[C@@]1(C)CCN2CC(O)=O
Show InChI InChI=1S/C16H21NO3/c1-10-14-7-11-3-4-12(18)8-13(11)16(10,2)5-6-17(14)9-15(19)20/h3-4,8,10,14,18H,5-7,9H2,1-2H3,(H,19,20)/t10-,14?,16-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 9.79E+3n/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Agonist activity at mu opioid receptor in Swiss mouse vas deferens assessed as inhibition of electrically-stimulated twitch


Bioorg Med Chem 16: 869-73 (2008)


Article DOI: 10.1016/j.bmc.2007.10.030
BindingDB Entry DOI: 10.7270/Q2XW4KN1
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(MOUSE)
BDBM50373764
PNG
(CHEMBL401590)
Show SMILES CCOC(=O)CCCN1CC[C@@]2(C)[C@@H](C)C1Cc1ccc(O)cc21
Show InChI InChI=1S/C20H29NO3/c1-4-24-19(23)6-5-10-21-11-9-20(3)14(2)18(21)12-15-7-8-16(22)13-17(15)20/h7-8,13-14,18,22H,4-6,9-12H2,1-3H3/t14-,18?,20-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.79E+4n/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Agonist activity at mu opioid receptor in Swiss mouse vas deferens assessed as inhibition of electrically-stimulated twitch


Bioorg Med Chem 16: 869-73 (2008)


Article DOI: 10.1016/j.bmc.2007.10.030
BindingDB Entry DOI: 10.7270/Q2XW4KN1
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(MOUSE)
BDBM50000092
PNG
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O
Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 395n/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Agonist activity at mu opioid receptor in Swiss mouse vas deferens assessed as inhibition of electrically-stimulated twitch


Bioorg Med Chem 16: 869-73 (2008)


Article DOI: 10.1016/j.bmc.2007.10.030
BindingDB Entry DOI: 10.7270/Q2XW4KN1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%