Compile Data Set for Download or QSAR
maximum 50k data
Found 83 Enz. Inhib. hit(s) with all data for entry = 50021595
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226096(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226064(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226086((S)-1-((3R,4R)-1-(4-cyanobenzyl)-3-aminopyrrolidin...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226093((1R)-2-((3R,4R)-1-(1-(4-(1H-1,2,4-triazol-1-yl)phe...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226077((3S,4S)-4-amino-3-(pyrrolidine-1-carbonyl)-1-(quin...)
Affinity DataIC50: >3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226065((S)-1-((3R,4R)-1-(4-(1H-1,2,4-triazol-1-yl)benzyl)...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226067((S)-1-((3R,4R)-1-(4-(1-methyl-1H-pyrazol-5-yl)benz...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226078(1-((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecarb...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226074((1R)-2-((3R,4R)-3-amino-1-(chroman-4-yl)pyrrolidin...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226084((S)-1-((3R,4R)-1-(3-cyano-4-fluorobenzyl)-3-aminop...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226076((1R)-2-((3R,4R)-1-(2-methyl-4-(1H-1,2,4-triazol-1-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226102(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226066((S)-1-((3R,4R)-1-(4-(3-methyl-1H-1,2,4-triazol-1-y...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226092((1R,3S)-2-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226075((S)-1-((3R,4R)-1-(4-(2H-1,2,3-triazol-2-yl)benzyl)...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226088((S)-1-((3R,4R)-3-amino-1-(1-(4-cyanophenyl)ethyl)p...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226080((S)-1-((3R,4R)-3-amino-1-(quinolin-3-ylmethyl)pyrr...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226099((S)-1-((3R,4R)-1-(4-(1H-pyrazol-5-yl)benzyl)-3-ami...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226071((S)-1-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226073((S)-1-((3R,4R)-1-(4-(1-methyl-1H-pyrazol-4-yl)benz...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226069((S)-1-((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226079(((3R,4R)-4-amino-1-quinolin-3-ylmethyl-pyrrolidin-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226101(CHEMBL249427 | [(3R,4R)-4-amino-1-(4-tetrazol-1-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226082(CHEMBL249620 | [(3R,4R)-4-amino-1-(quinoline-6-car...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226083(CHEMBL401268 | [(3R,4R)-4-amino-1-(4-[1,2,4]triazo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226089(CHEMBL399247 | [(3R,4R)-4-amino-1-(benzothiazole-6...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226072((1R)-2-((3R,4R)-1-(3-methyl-4-(1H-1,2,4-triazol-1-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226070(CHEMBL249825 | [(3R,4R)-4-amino-1-(isoquinoline-3-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226100(CHEMBL249826 | [(3R,4R)-4-amino-1-(quinoline-3-car...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226098(CHEMBL250393 | [(3R,4R)-4-amino-1-(4-tetrazol-1-yl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226097(CHEMBL248837 | [(3R,4R)-4-amino-1-(benzo[b]thiophe...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226094((3R,4R)-4-amino-3-(pyrrolidine-1-carbonyl)-1-(quin...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226087(CHEMBL249174 | [(3R,4R)-4-amino-1-(4-[1,2,4]triazo...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226095(5-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226091(CHEMBL248838 | [(3R,4R)-4-amino-1-(naphthalene-2-c...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226068(((3R,4R)-1-(3,4-difluorobenzyl)-4-aminopyrrolidin-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226081(4-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226090(((3R,4R)-4-amino-1-(1-(4-nitrophenyl)ethyl)pyrroli...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226063(CHEMBL401269 | [(3R,4R)-4-amino-1-(5-chloro-benzof...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226085(((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)-4-ami...)
Affinity DataIC50:  91nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226085(((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)-4-ami...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226098(CHEMBL250393 | [(3R,4R)-4-amino-1-(4-tetrazol-1-yl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226090(((3R,4R)-4-amino-1-(1-(4-nitrophenyl)ethyl)pyrroli...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226065((S)-1-((3R,4R)-1-(4-(1H-1,2,4-triazol-1-yl)benzyl)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of hERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226081(4-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226068(((3R,4R)-1-(3,4-difluorobenzyl)-4-aminopyrrolidin-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226095(5-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226063(CHEMBL401269 | [(3R,4R)-4-amino-1-(5-chloro-benzof...)
Affinity DataIC50:  4.25E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226087(CHEMBL249174 | [(3R,4R)-4-amino-1-(4-[1,2,4]triazo...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226079(((3R,4R)-4-amino-1-quinolin-3-ylmethyl-pyrrolidin-...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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