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PubMed code 18337096

Compile data set for download or QSAR
Found 37 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 4.5n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375106
PNG
(CHEMBL256262)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C22H19BrCl2N6/c1-13-20(22-26-28-29-30(22)17-4-2-3-5-17)27-31(19-11-10-16(24)12-18(19)25)21(13)14-6-8-15(23)9-7-14/h6-12,17H,2-5H2,1H3
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n/an/a 11.6n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375099
PNG
(CHEMBL404282)
Show SMILES CCc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C23H21BrCl2N6/c1-2-18-21(23-27-29-30-31(23)17-5-3-4-6-17)28-32(20-12-11-16(25)13-19(20)26)22(18)14-7-9-15(24)10-8-14/h7-13,17H,2-6H2,1H3
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n/an/a 14.2n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375101
PNG
(CHEMBL255197)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCCCC1
Show InChI InChI=1S/C24H23BrCl2N6/c1-15-22(24-28-30-31-32(24)19-6-4-2-3-5-7-19)29-33(21-13-12-18(26)14-20(21)27)23(15)16-8-10-17(25)11-9-16/h8-14,19H,2-7H2,1H3
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n/an/a 16.5n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375100
PNG
(CHEMBL270663)
Show SMILES CCc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C23H21Cl3N6/c1-2-18-21(23-27-29-30-31(23)17-5-3-4-6-17)28-32(20-12-11-16(25)13-19(20)26)22(18)14-7-9-15(24)10-8-14/h7-13,17H,2-6H2,1H3
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n/an/a 22.6n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375103
PNG
(CHEMBL402555)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C22H19Cl3N6/c1-13-20(22-26-28-29-30(22)17-4-2-3-5-17)27-31(19-11-10-16(24)12-18(19)25)21(13)14-6-8-15(23)9-7-14/h6-12,17H,2-5H2,1H3
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n/an/a 26.5n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375102
PNG
(CHEMBL263915)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCCCC1
Show InChI InChI=1S/C24H23Cl3N6/c1-15-22(24-28-30-31-32(24)19-6-4-2-3-5-7-19)29-33(21-13-12-18(26)14-20(21)27)23(15)16-8-10-17(25)11-9-16/h8-14,19H,2-7H2,1H3
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n/an/a 26.7n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375090
PNG
(CHEMBL257309)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1-c1ccccc1
Show InChI InChI=1S/C23H15Cl3N6/c1-14-21(23-27-29-30-31(23)18-5-3-2-4-6-18)28-32(20-12-11-17(25)13-19(20)26)22(14)15-7-9-16(24)10-8-15/h2-13H,1H3
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n/an/a 33.8n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375087
PNG
(CHEMBL402631)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCC1
Show InChI InChI=1S/C21H17Cl3N6/c1-12-19(21-25-27-28-29(21)16-3-2-4-16)26-30(18-10-9-15(23)11-17(18)24)20(12)13-5-7-14(22)8-6-13/h5-11,16H,2-4H2,1H3
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n/an/a 42.3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375091
PNG
(CHEMBL272721)
Show SMILES CCCCCCCCn1nnnc1-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C25H27Cl3N6/c1-3-4-5-6-7-8-15-33-25(29-31-32-33)23-17(2)24(18-9-11-19(26)12-10-18)34(30-23)22-14-13-20(27)16-21(22)28/h9-14,16H,3-8,15H2,1-2H3
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n/an/a 47.3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375082
PNG
(CHEMBL271436)
Show SMILES CCCCCCCCn1nnc(n1)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C25H27Cl3N6/c1-3-4-5-6-7-8-15-33-31-25(29-32-33)23-17(2)24(18-9-11-19(26)12-10-18)34(30-23)22-14-13-20(27)16-21(22)28/h9-14,16H,3-8,15H2,1-2H3
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n/an/a 50.6n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375086
PNG
(CHEMBL262880)
Show SMILES CCCn1nnc(n1)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H17Cl3N6/c1-3-10-28-26-20(24-27-28)18-12(2)19(13-4-6-14(21)7-5-13)29(25-18)17-9-8-15(22)11-16(17)23/h4-9,11H,3,10H2,1-2H3
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n/an/a 62.1n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375109
PNG
(CHEMBL255201)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnn(n1)C1CCCC1
Show InChI InChI=1S/C22H19Cl3N6/c1-13-20(22-26-29-31(28-22)17-4-2-3-5-17)27-30(19-11-10-16(24)12-18(19)25)21(13)14-6-8-15(23)9-7-14/h6-12,17H,2-5H2,1H3
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n/an/a 67.9n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375096
PNG
(CHEMBL257842)
Show SMILES CCCn1nnnc1-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H17Cl3N6/c1-3-10-28-20(24-26-27-28)18-12(2)19(13-4-6-14(21)7-5-13)29(25-18)17-9-8-15(22)11-16(17)23/h4-9,11H,3,10H2,1-2H3
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n/an/a 68.9n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375108
PNG
(CHEMBL271092)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnn(n1)C1CCCCC1
Show InChI InChI=1S/C23H21Cl3N6/c1-14-21(23-27-30-32(29-23)18-5-3-2-4-6-18)28-31(20-12-11-17(25)13-19(20)26)22(14)15-7-9-16(24)10-8-15/h7-13,18H,2-6H2,1H3
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n/an/a 75.8n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375107
PNG
(CHEMBL272723)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnn(CC2CCCCC2)n1
Show InChI InChI=1S/C24H23Cl3N6/c1-15-22(24-28-31-32(30-24)14-16-5-3-2-4-6-16)29-33(21-12-11-19(26)13-20(21)27)23(15)17-7-9-18(25)10-8-17/h7-13,16H,2-6,14H2,1H3
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n/an/a 85.3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375084
PNG
(CHEMBL410538)
Show SMILES CCCCn1nnc(n1)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H19Cl3N6/c1-3-4-11-29-27-21(25-28-29)19-13(2)20(14-5-7-15(22)8-6-14)30(26-19)18-10-9-16(23)12-17(18)24/h5-10,12H,3-4,11H2,1-2H3
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n/an/a 87.7n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375094
PNG
(CHEMBL401678)
Show SMILES CCCCn1nnnc1-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H19Cl3N6/c1-3-4-11-29-21(25-27-28-29)19-13(2)20(14-5-7-15(22)8-6-14)30(26-19)18-10-9-16(23)12-17(18)24/h5-10,12H,3-4,11H2,1-2H3
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n/an/a 87.8n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375089
PNG
(CHEMBL257310)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1Cc1ccccc1
Show InChI InChI=1S/C24H17Cl3N6/c1-15-22(24-28-30-31-32(24)14-16-5-3-2-4-6-16)29-33(21-12-11-19(26)13-20(21)27)23(15)17-7-9-18(25)10-8-17/h2-13H,14H2,1H3
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n/an/a 94.3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375085
PNG
(CHEMBL410875)
Show SMILES CC(C)n1nnc(n1)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H17Cl3N6/c1-11(2)29-26-20(24-27-29)18-12(3)19(13-4-6-14(21)7-5-13)28(25-18)17-9-8-15(22)10-16(17)23/h4-11H,1-3H3
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n/an/a 101n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375110
PNG
(CHEMBL255203)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnn(Cc2ccccc2)n1
Show InChI InChI=1S/C24H17Cl3N6/c1-15-22(24-28-31-32(30-24)14-16-5-3-2-4-6-16)29-33(21-12-11-19(26)13-20(21)27)23(15)17-7-9-18(25)10-8-17/h2-13H,14H2,1H3
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n/an/a 105n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375083
PNG
(CHEMBL272539)
Show SMILES CCCCCn1nnc(n1)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H21Cl3N6/c1-3-4-5-12-30-28-22(26-29-30)20-14(2)21(15-6-8-16(23)9-7-15)31(27-20)19-11-10-17(24)13-18(19)25/h6-11,13H,3-5,12H2,1-2H3
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n/an/a 122n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375095
PNG
(CHEMBL401679)
Show SMILES CC(C)n1nnnc1-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H17Cl3N6/c1-11(2)28-20(24-26-27-28)18-12(3)19(13-4-6-14(21)7-5-13)29(25-18)17-9-8-15(22)10-16(17)23/h4-11H,1-3H3
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n/an/a 166n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375088
PNG
(CHEMBL257690)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CC1
Show InChI InChI=1S/C20H15Cl3N6/c1-11-18(20-24-26-27-28(20)15-7-8-15)25-29(17-9-6-14(22)10-16(17)23)19(11)12-2-4-13(21)5-3-12/h2-6,9-10,15H,7-8H2,1H3
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n/an/a 181n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375092
PNG
(CHEMBL272507)
Show SMILES CCCCCn1nnnc1-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H21Cl3N6/c1-3-4-5-12-30-22(26-28-29-30)20-14(2)21(15-6-8-16(23)9-7-15)31(27-20)19-11-10-17(24)13-18(19)25/h6-11,13H,3-5,12H2,1-2H3
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n/an/a 184n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375097
PNG
(CHEMBL404485)
Show SMILES CCn1nnnc1-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C19H15Cl3N6/c1-3-27-19(23-25-26-27)17-11(2)18(12-4-6-13(20)7-5-12)28(24-17)16-9-8-14(21)10-15(16)22/h4-10H,3H2,1-2H3
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n/an/a 202n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375093
PNG
(CHEMBL272722)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C(C)(C)C
Show InChI InChI=1S/C21H19Cl3N6/c1-12-18(20-25-27-28-30(20)21(2,3)4)26-29(17-10-9-15(23)11-16(17)24)19(12)13-5-7-14(22)8-6-13/h5-11H,1-4H3
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n/an/a 361n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50375102
PNG
(CHEMBL263915)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCCCC1
Show InChI InChI=1S/C24H23Cl3N6/c1-15-22(24-28-30-31-32(24)19-6-4-2-3-5-7-19)29-33(21-13-12-18(26)14-20(21)27)23(15)16-8-10-17(25)11-9-16/h8-14,19H,2-7H2,1H3
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n/an/a 818n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN-55212-2 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50375100
PNG
(CHEMBL270663)
Show SMILES CCc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C23H21Cl3N6/c1-2-18-21(23-27-29-30-31(23)17-5-3-4-6-17)28-32(20-12-11-16(25)13-19(20)26)22(18)14-7-9-15(24)10-8-14/h7-13,17H,2-6H2,1H3
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n/an/a 840n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN-55212-2 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375104
PNG
(CHEMBL261464)
Show SMILES CCn1nnc(n1)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C19H15Cl3N6/c1-3-27-25-19(23-26-27)17-11(2)18(12-4-6-13(20)7-5-12)28(24-17)16-9-8-14(21)10-15(16)22/h4-10H,3H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375105
PNG
(CHEMBL263914)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnn(C)n1
Show InChI InChI=1S/C18H13Cl3N6/c1-10-16(18-22-25-26(2)24-18)23-27(15-8-7-13(20)9-14(15)21)17(10)11-3-5-12(19)6-4-11/h3-9H,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50375098
PNG
(CHEMBL258086)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C
Show InChI InChI=1S/C18H13Cl3N6/c1-10-16(18-22-24-25-26(18)2)23-27(15-8-7-13(20)9-14(15)21)17(10)11-3-5-12(19)6-4-11/h3-9H,1-2H3
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n/an/a 1.06E+3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of cannabinoid CB1 receptor in Sprague-Dawley rat brain


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 1.76E+3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN-55212-2 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50375099
PNG
(CHEMBL404282)
Show SMILES CCc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C23H21BrCl2N6/c1-2-18-21(23-27-29-30-31(23)17-5-3-4-6-17)28-32(20-12-11-16(25)13-19(20)26)22(18)14-7-9-15(24)10-8-14/h7-13,17H,2-6H2,1H3
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n/an/a 1.93E+3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN-55212-2 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50375106
PNG
(CHEMBL256262)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C22H19BrCl2N6/c1-13-20(22-26-28-29-30(22)17-4-2-3-5-17)27-31(19-11-10-16(24)12-18(19)25)21(13)14-6-8-15(23)9-7-14/h6-12,17H,2-5H2,1H3
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n/an/a 4.24E+3n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN-55212-2 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50375103
PNG
(CHEMBL402555)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Show InChI InChI=1S/C22H19Cl3N6/c1-13-20(22-26-28-29-30(22)17-4-2-3-5-17)27-31(19-11-10-16(24)12-18(19)25)21(13)14-6-8-15(23)9-7-14/h6-12,17H,2-5H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN-55212-2 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50375101
PNG
(CHEMBL255197)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCCCC1
Show InChI InChI=1S/C24H23BrCl2N6/c1-15-22(24-28-30-31-32(24)19-6-4-2-3-5-7-19)29-33(21-13-12-18(26)14-20(21)27)23(15)16-8-10-17(25)11-9-16/h8-14,19H,2-7H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



reen Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN-55212-2 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 2385-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.061
BindingDB Entry DOI: 10.7270/Q2GF0VCQ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%