Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 2847
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25237(N-(2-aminophenyl)-4-{3-cyano-5-[(4-ethylpiperazin-...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25241(N-(2-aminophenyl)-4-(3-cyano-5-{[4-(propan-2-yl)pi...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25233(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-cya...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25231(N-(2-aminophenyl)-4-(3-cyanopyridin-2-yl)benzamide...)
Affinity DataIC50:  12nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25242(N-(2-aminophenyl)-4-(3-chloro-5-{[4-(propan-2-yl)p...)
Affinity DataIC50:  13nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25238(N-(2-aminophenyl)-4-{3-chloro-5-[(4-ethylpiperazin...)
Affinity DataIC50:  16nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25240(N-(2-aminophenyl)-4-(3-methyl-5-{[4-(propan-2-yl)p...)
Affinity DataIC50:  19nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25234(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-chl...)
Affinity DataIC50:  19nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25236(N-(2-aminophenyl)-4-{5-[(4-ethylpiperazin-1-yl)met...)
Affinity DataIC50:  19nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25232(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-met...)
Affinity DataIC50:  21nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25243(N-(2-aminophenyl)-4-(3-fluoro-5-{[4-(propan-2-yl)p...)
Affinity DataIC50:  33nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25239(N-(2-aminophenyl)-4-{5-[(4-ethylpiperazin-1-yl)met...)
Affinity DataIC50:  38nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25235(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-flu...)
Affinity DataIC50:  50nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed