Affinity Data by PubMed id=1849993

PubMed code 1849993

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50001285 ((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009073 (4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009075 (CHEMBL22033 \| ICI 198615 \| ICI-198615 \| [1-(4-Benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50006799 (2-{4-[2-(1H-Tetrazol-5-ylmethyl)-benzyloxy]-phenox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009070 ((2S,3R)-3-(2-Carboxy-ethylsulfanyl)-2-hydroxy-3-[2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009069 ((S)-3-(2-Carboxy-ethylsulfanyl)-3-[2-(8-phenyl-oct...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009072 ((3R,4S)-4-{4-[3-(4-Acetyl-3-hydroxy-2-propyl-pheno...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50006812 (7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50006798 (2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009068 (7-[(2E,4E,6Z,9E)-(R)-1-((R)-4-Carboxy-1-hydroxy-bu...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009071 (6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) Article DOI: 10.1021/jm00108a001 BindingDB Entry DOI: 10.7270/Q2K936HB
ICI Pharmaceuticals Group Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%