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PubMed code 18579376

Compile data set for download or QSAR
Found 23 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27542
PNG
(4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H...)
Show SMILES O=C(N1CCNCC1)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
Show InChI InChI=1S/C20H20N4O2/c25-19-17-7-2-1-6-16(17)18(22-23-19)13-14-4-3-5-15(12-14)20(26)24-10-8-21-9-11-24/h1-7,12,21H,8-11,13H2,(H,23,25)
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n/an/a 2n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27662
PNG
(4-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...)
Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
Show InChI InChI=1S/C29H28N4O4/c1-20(37-23-10-3-2-4-11-23)28(35)32-14-16-33(17-15-32)29(36)22-9-7-8-21(18-22)19-26-24-12-5-6-13-25(24)27(34)31-30-26/h2-13,18,20H,14-17,19H2,1H3,(H,31,34)
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n/an/a 5n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27661
PNG
(4-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Show SMILES O=C(C1CCCC1)N1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
Show InChI InChI=1S/C26H28N4O3/c31-24-22-11-4-3-10-21(22)23(27-28-24)17-18-6-5-9-20(16-18)26(33)30-14-12-29(13-15-30)25(32)19-7-1-2-8-19/h3-6,9-11,16,19H,1-2,7-8,12-15,17H2,(H,28,31)
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n/an/a 8n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27680
PNG
(2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Show SMILES NC(=O)c1cc(F)ccc1OCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1
Show InChI InChI=1S/C25H27F2N3O4/c26-18-6-8-22(20(14-18)23(28)31)34-15-16-5-7-21(27)19(13-16)25(33)30-11-9-29(10-12-30)24(32)17-3-1-2-4-17/h5-8,13-14,17H,1-4,9-12,15H2,(H2,28,31)
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n/an/a 12n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27681
PNG
(5-fluoro-2-[(4-fluoro-3-{[4-(2-phenoxypropanoyl)pi...)
Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cc(COc2ccc(F)cc2C(N)=O)ccc1F
Show InChI InChI=1S/C28H27F2N3O5/c1-18(38-21-5-3-2-4-6-21)27(35)32-11-13-33(14-12-32)28(36)22-15-19(7-9-24(22)30)17-37-25-10-8-20(29)16-23(25)26(31)34/h2-10,15-16,18H,11-14,17H2,1H3,(H2,31,34)
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KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27663
PNG
(2-{[3-(piperazin-1-ylcarbonyl)phenyl]methoxy}benza...)
Show SMILES NC(=O)c1ccccc1OCc1cccc(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C19H21N3O3/c20-18(23)16-6-1-2-7-17(16)25-13-14-4-3-5-15(12-14)19(24)22-10-8-21-9-11-22/h1-7,12,21H,8-11,13H2,(H2,20,23)
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n/an/a 18n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27674
PNG
(2-[2-(4-fluoro-3-{[4-(2-phenoxypropanoyl)piperazin...)
Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cc(CCOc2ccccc2C(N)=O)ccc1F
Show InChI InChI=1S/C29H30FN3O5/c1-20(38-22-7-3-2-4-8-22)28(35)32-14-16-33(17-15-32)29(36)24-19-21(11-12-25(24)30)13-18-37-26-10-6-5-9-23(26)27(31)34/h2-12,19-20H,13-18H2,1H3,(H2,31,34)
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n/an/a 19n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27666
PNG
(2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Show SMILES NC(=O)c1ccccc1OCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1
Show InChI InChI=1S/C25H28FN3O4/c26-21-10-9-17(16-33-22-8-4-3-7-19(22)23(27)30)15-20(21)25(32)29-13-11-28(12-14-29)24(31)18-5-1-2-6-18/h3-4,7-10,15,18H,1-2,5-6,11-14,16H2,(H2,27,30)
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n/an/a 24n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27675
PNG
(5-fluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)ph...)
Show SMILES NC(=O)c1cc(F)ccc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C19H19F2N3O3/c20-13-2-4-17(15(10-13)18(22)25)27-11-12-1-3-16(21)14(9-12)19(26)24-7-5-23-6-8-24/h1-4,9-10,23H,5-8,11H2,(H2,22,25)
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KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27667
PNG
(2-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...)
Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(COc2ccccc2C(N)=O)c1
Show InChI InChI=1S/C28H29N3O5/c1-20(36-23-10-3-2-4-11-23)27(33)30-14-16-31(17-15-30)28(34)22-9-7-8-21(18-22)19-35-25-13-6-5-12-24(25)26(29)32/h2-13,18,20H,14-17,19H2,1H3,(H2,29,32)
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KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27668
PNG
(2-[(4-fluoro-3-{[4-(2-phenoxypropanoyl)piperazin-1...)
Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cc(COc2ccccc2C(N)=O)ccc1F
Show InChI InChI=1S/C28H28FN3O5/c1-19(37-21-7-3-2-4-8-21)27(34)31-13-15-32(16-14-31)28(35)23-17-20(11-12-24(23)29)18-36-25-10-6-5-9-22(25)26(30)33/h2-12,17,19H,13-16,18H2,1H3,(H2,30,33)
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KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27664
PNG
(2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]meth...)
Show SMILES NC(=O)c1ccccc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C19H20FN3O3/c20-16-6-5-13(11-15(16)19(25)23-9-7-22-8-10-23)12-26-17-4-2-1-3-14(17)18(21)24/h1-6,11,22H,7-10,12H2,(H2,21,24)
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KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27672
PNG
(2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...)
Show SMILES NC(=O)c1ccccc1OCCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1
Show InChI InChI=1S/C26H30FN3O4/c27-22-10-9-18(11-16-34-23-8-4-3-7-20(23)24(28)31)17-21(22)26(33)30-14-12-29(13-15-30)25(32)19-5-1-2-6-19/h3-4,7-10,17,19H,1-2,5-6,11-16H2,(H2,28,31)
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Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27665
PNG
(2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Show SMILES NC(=O)c1ccccc1OCc1cccc(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1
Show InChI InChI=1S/C25H29N3O4/c26-23(29)21-10-3-4-11-22(21)32-17-18-6-5-9-20(16-18)25(31)28-14-12-27(13-15-28)24(30)19-7-1-2-8-19/h3-6,9-11,16,19H,1-2,7-8,12-15,17H2,(H2,26,29)
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Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27671
PNG
(2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...)
Show SMILES NC(=O)c1ccccc1OCCc1cccc(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1
Show InChI InChI=1S/C26H31N3O4/c27-24(30)22-10-3-4-11-23(22)33-17-12-19-6-5-9-21(18-19)26(32)29-15-13-28(14-16-29)25(31)20-7-1-2-8-20/h3-6,9-11,18,20H,1-2,7-8,12-17H2,(H2,27,30)
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Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27673
PNG
(2-[2-(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]car...)
Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(CCOc2ccccc2C(N)=O)c1
Show InChI InChI=1S/C29H31N3O5/c1-21(37-24-10-3-2-4-11-24)28(34)31-15-17-32(18-16-31)29(35)23-9-7-8-22(20-23)14-19-36-26-13-6-5-12-25(26)27(30)33/h2-13,20-21H,14-19H2,1H3,(H2,30,33)
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Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27676
PNG
(4,5-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...)
Show SMILES NC(=O)c1cc(F)c(F)cc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C19H18F3N3O3/c20-14-2-1-11(7-12(14)19(27)25-5-3-24-4-6-25)10-28-17-9-16(22)15(21)8-13(17)18(23)26/h1-2,7-9,24H,3-6,10H2,(H2,23,26)
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Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27677
PNG
(4-fluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)ph...)
Show SMILES NC(=O)c1ccc(F)cc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C19H19F2N3O3/c20-13-2-3-14(18(22)25)17(10-13)27-11-12-1-4-16(21)15(9-12)19(26)24-7-5-23-6-8-24/h1-4,9-10,23H,5-8,11H2,(H2,22,25)
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KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27660
PNG
(4-Benzyl-2H-phthalazin-1-one | 4-benzyl-1,2-dihydr...)
Show SMILES O=c1[nH]nc(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C15H12N2O/c18-15-13-9-5-4-8-12(13)14(16-17-15)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,17,18)
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PubMed
n/an/a 770n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27669
PNG
(2-{2-[3-(piperazin-1-ylcarbonyl)phenyl]ethoxy}benz...)
Show SMILES NC(=O)c1ccccc1OCCc1cccc(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C20H23N3O3/c21-19(24)17-6-1-2-7-18(17)26-13-8-15-4-3-5-16(14-15)20(25)23-11-9-22-10-12-23/h1-7,14,22H,8-13H2,(H2,21,24)
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PubMed
n/an/a 970n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27678
PNG
(3,5-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...)
Show SMILES NC(=O)c1cc(F)cc(F)c1OCc1ccc(F)c(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C19H18F3N3O3/c20-12-8-14(18(23)26)17(16(22)9-12)28-10-11-1-2-15(21)13(7-11)19(27)25-5-3-24-4-6-25/h1-2,7-9,24H,3-6,10H2,(H2,23,26)
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UniChem

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PubMed
n/an/a 1.50E+3n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27679
PNG
(3,6-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...)
Show SMILES NC(=O)c1c(F)ccc(F)c1OCc1ccc(F)c(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C19H18F3N3O3/c20-13-2-1-11(9-12(13)19(27)25-7-5-24-6-8-25)10-28-17-15(22)4-3-14(21)16(17)18(23)26/h1-4,9,24H,5-8,10H2,(H2,23,26)
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PubMed
n/an/a>1.00E+4n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27670
PNG
(2-{2-[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]et...)
Show SMILES NC(=O)c1ccccc1OCCc1ccc(F)c(c1)C(=O)N1CCNCC1
Show InChI InChI=1S/C20H22FN3O3/c21-17-6-5-14(13-16(17)20(26)24-10-8-23-9-11-24)7-12-27-18-4-2-1-3-15(18)19(22)25/h1-6,13,23H,7-12H2,(H2,22,25)
PDB
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UniProtKB/SwissProt

B.MOAD
GoogleScholar
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UniChem

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Article
PubMed
n/an/a>1.00E+4n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...


Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%