Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50026612
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263192(CHEMBL478858 | CHEMBL564483 | Pactimibe | [7-(2,2-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL after differentiation assessed as effect on...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263196(CHEMBL478015 | N-(5-Aminomethyl-4,6-dimethyl-1-oct...)
Affinity DataIC50:  330nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263150(CHEMBL513892 | N-(4,6-dimethyl-1-octylindolin-7-yl...)
Affinity DataIC50:  640nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50069900(2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263192(CHEMBL478858 | CHEMBL564483 | Pactimibe | [7-(2,2-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263193(3-[4,6-Dimethyl-7-(2,2-dimethylpropanamido)-1-octy...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263195(4-(4,6-Dimethyl-1-octylindolin-7-yl)carbamoyl-4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263241(CHEMBL514043 | N-[4,6-Dimethyl-1-octyl-5-(1H-tetra...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263194(10-[7-(2,2-Dimethylpropanamido)-4,6-dimethylindoli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed