Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50026658
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262553((9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261956(9'-(6-Hydroxy-8-oxospiro[3.5]non-7-yl)-4',9'-dihyd...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262001(9'-(7-Hydroxy-9-oxospiro[4.5]dec-8-yl)-4',9'-dihyd...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261955(9-(4,4-Diethyl-2-hydroxy-6-oxocyclohexyl)-3,3-diet...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262002(9'-(2-Hydroxy-4-oxospiro[5.5]undec-3-yl)-4',9'-dih...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261897(6-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1O...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261898(5-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261724(6-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261899(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3,6-t...)
Affinity DataKi:  36nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261952(6-Bromo-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)...)
Affinity DataKi:  36nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261900(6-Ethyl-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261725(5-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261787(7-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  81nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261721(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-6-metho...)
Affinity DataKi:  93nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261954(9-(2-Hydroxy-4-methyl-6-oxocyclohexyl)-3-methyl-2,...)
Affinity DataKi:  193nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261723(7-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  197nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262552((9R)-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-eny...)
Affinity DataKi:  343nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262555(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-7-metho...)
Affinity DataKi:  590nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261901(6-Ethoxy-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  833nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262554(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-8-metho...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261953(9-(2-Hydroxy-6-oxocyclohexyl)-2,3,4,9-tetrahydro-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261722(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-5-metho...)
Affinity DataKi:  2.17E+3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262553((9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-...)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261956(9'-(6-Hydroxy-8-oxospiro[3.5]non-7-yl)-4',9'-dihyd...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262001(9'-(7-Hydroxy-9-oxospiro[4.5]dec-8-yl)-4',9'-dihyd...)
Affinity DataIC50:  58nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1O...)
Affinity DataIC50:  61nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261897(6-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261898(5-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataIC50:  73nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261952(6-Bromo-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)...)
Affinity DataIC50:  81nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261724(6-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261955(9-(4,4-Diethyl-2-hydroxy-6-oxocyclohexyl)-3,3-diet...)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262002(9'-(2-Hydroxy-4-oxospiro[5.5]undec-3-yl)-4',9'-dih...)
Affinity DataIC50:  109nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261899(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3,6-t...)
Affinity DataIC50:  111nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262552((9R)-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-eny...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1O...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human neuropeptide Y1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1O...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human neuropeptide Y2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1O...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human neuropeptide Y4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed