Compile Data Set for Download or QSAR
maximum 50k data
Found 93 Enz. Inhib. hit(s) with all data for entry = 50026811
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human Tie2 (unknown origin) autophosphorylation expressed in CHOK1 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272215((E/Z)-4-(2-(4-phenyl-1H-imidazol-5-yl)vinyl)pyrimi...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human Tie2 (unknown origin) autophosphorylation expressed in CHOK1 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human recombinant Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272265((E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272309(4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)ethynyl)p...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272213((E/Z)-4-(2-(6-phenyl-2,3-dihydroimidazo[2,1-b]thia...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272213((E/Z)-4-(2-(6-phenyl-2,3-dihydroimidazo[2,1-b]thia...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272072((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272159((E/Z)-6-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272159((E/Z)-6-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272163((E/Z)-4-(2-(2-phenylH-imidazo[1,2-a]pyridin-3-yl)v...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272586((E/Z)-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272309(4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)ethynyl)p...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272586((E/Z)-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272265((E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272216((E/Z)-4-(2-(1-methyl-5-phenyl-1H-imidazol-4-yl)vin...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272215((E/Z)-4-(2-(4-phenyl-1H-imidazol-5-yl)vinyl)pyrimi...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272215((E/Z)-4-(2-(4-phenyl-1H-imidazol-5-yl)vinyl)pyrimi...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272072((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272073((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272587((E/Z)-4-(2-(6-(p-fluoro-phenyl)imidazo[2,1-b]thiaz...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272163((E/Z)-4-(2-(2-phenylH-imidazo[1,2-a]pyridin-3-yl)v...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272590((E/Z)-N-methyl-4-(2-(6-phenylimidazo[2,1-b]thiazol...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272590((E/Z)-N-methyl-4-(2-(6-phenylimidazo[2,1-b]thiazol...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272264((E/Z)-4-(2-(4-phenyl-1-(2-(pyrrolidin-1-yl)ethyl)-...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272213((E/Z)-4-(2-(6-phenyl-2,3-dihydroimidazo[2,1-b]thia...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272101((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272586((E/Z)-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272265((E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272589((E/Z)-4-(2-(6-chloroimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272264((E/Z)-4-(2-(4-phenyl-1-(2-(pyrrolidin-1-yl)ethyl)-...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272159((E/Z)-6-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272309(4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)ethynyl)p...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272073((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272074((E/Z)-5-(2-(2-chloropyrimidin-4-yl)vinyl)-6-phenyl...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272161((E/Z)-4-(2-(4-phenyl-1H-pyrazol-5-yl)vinyl)pyrimid...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272074((E/Z)-5-(2-(2-chloropyrimidin-4-yl)vinyl)-6-phenyl...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272218((E/Z)-2-(5-(2-(2-aminopyrimidin-4-yl)vinyl)-4-phen...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272215((E/Z)-4-(2-(4-phenyl-1H-imidazol-5-yl)vinyl)pyrimi...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272071((E/Z)-N-phenyl-4-(2-(6-phenylimidazo[2,1-b]thiazol...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272588((E/Z)-4-(2-(6-methylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272590((E/Z)-N-methyl-4-(2-(6-phenylimidazo[2,1-b]thiazol...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272101((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272163((E/Z)-4-(2-(2-phenylH-imidazo[1,2-a]pyridin-3-yl)v...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272160((E/Z)-4-(2-(1-methyl-2-phenyl-1H-indol-3-yl)vinyl)...)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272070(CHEMBL502803 | N-(1-phenylethyl)-4-(2-(6-phenylimi...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272073((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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