Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009407![]() (But-3-enoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009411![]() (6-{2-[8-(4-Fluoro-benzyloxy)-2,6-dimethyl-1,2,6,7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009413![]() (CHEMBL3085466 | Phenyl-acetic acid 8-[2-(4-hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009414![]() (6-[2-(8-Benzyloxy-2,6-dimethyl-1,2,6,7,8,8a-hexahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009409![]() (6-{2-[8-(4-Chloro-benzyloxy)-2,6-dimethyl-1,2,6,7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009408![]() (Acetic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 269 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009415![]() (6-{2-[2,6-Dimethyl-8-(2-methyl-allyloxy)-1,2,6,7,8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009410![]() (6-[2-(8-Allyloxy-2,6-dimethyl-1,2,6,7,8,8a-hexahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM50009412![]() (4-Hydroxy-6-[2-(8-methoxy-2,6-dimethyl-1,2,6,7,8,8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzyme | J Med Chem 34: 2474-7 (1991) Article DOI: 10.1021/jm00112a024 BindingDB Entry DOI: 10.7270/Q29S1Q0D | |||||||||||
More data for this Ligand-Target Pair |