Affinity Data by PubMed id=1875352

PubMed code 1875352

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009591 (1-(2-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCCC1(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009591 (1-(2-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCCC1(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride \| M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009591 (1-(2-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCCC1(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009592 (CHEMBL424610 \| cis-1-(4-Methyl-1-phenyl-cyclohexyl...) Show SMILES CC1CCC(CC1)(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009592 (CHEMBL424610 \| cis-1-(4-Methyl-1-phenyl-cyclohexyl...) Show SMILES CC1CCC(CC1)(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	617	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009591 (1-(2-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCCC1(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009591 (1-(2-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCCC1(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009590 (CHEMBL86824 \| cis-C-(2-Methyl-1-piperidin-1-yl-cyc...) Show SMILES CC1CCCCC1(N1CCCCC1)C(=N)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009591 (1-(2-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCCC1(N1CCCCC1)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009590 (CHEMBL86824 \| cis-C-(2-Methyl-1-piperidin-1-yl-cyc...) Show SMILES CC1CCCCC1(N1CCCCC1)C(=N)c1ccccc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009593 (C-Phenyl-C-(1-piperidin-1-yl-cyclohexyl)-methylene...) Show SMILES N=C(c1ccccc1)C1(CCCCC1)N1CCCCC1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...				J Med Chem 34: 2615-23 (1991) Article DOI: 10.1021/jm00112a041 BindingDB Entry DOI: 10.7270/Q22806K3
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%