Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50027131
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264878((cis)-4-((2-(4-((E)-3-morpholino-3-oxoprop-1-enyl)...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264880((trans)-4-((2-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265320((trans)-4-(2-(4-((E)-3-morpholino-3-oxoprop-1-enyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265147((E)-1-morpholino-3-(4-(2-(piperidin-4-yloxy)phenyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265190((E)-1-morpholino-3-(4-(3-(tetrahydro-2H-thiopyran-...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265149((E)-1-morpholino-3-(4-(2-(tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264778((E)-1-morpholino-3-(4-(2-(pyridin-3-ylmethoxy)phen...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265286((cis)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264879((cis)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264881((trans)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264876((E)-1-morpholino-3-(4-(2-(pyridin-4-ylmethoxy)phen...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265148((E)-1-morpholino-3-(4-(3-(piperidin-4-yloxy)phenyl...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265285((cis)-4-(2-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265106((E)-3-(4-(2-(cyclohexyloxy)phenylthio)-2,3-bis(tri...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265322((E)-3-(4-(2-((1H-imidazol-4-yl)methoxy)phenylthio)...)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264753((E)-1-morpholino-3-(4-(2-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265366((E)-1-morpholino-3-(4-(2-(thiophen-2-ylmethoxy)phe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265246((E)-3-(4-(2-((cis)-4-methylcyclohexyloxy)phenylthi...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265321((trans)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265367((E)-3-(4-(2-(benzyloxy)phenylthio)-2,3-bis(trifluo...)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265188((E)-1-morpholino-3-(4-(3-(tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50:  34nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265248((E)-3-(4-(2-((trans)-4-methylcyclohexyloxy)phenylt...)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264877((E)-1-morpholino-3-(4-(3-(pyridin-4-ylmethoxy)phen...)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265189((E)-1-morpholino-3-(4-(2-(tetrahydro-2H-thiopyran-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265365((E)-3-(4-(3-((1H-imidazol-4-yl)methoxy)phenylthio)...)
Affinity DataIC50:  68nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264875((E)-1-morpholino-3-(4-(3-(pyridin-3-ylmethoxy)phen...)
Affinity DataIC50:  69nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264754((E)-1-morpholino-3-(4-(3-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264752((E)-3-(4-(3-(benzyloxy)phenylthio)-2,3-bis(trifluo...)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265107((E)-3-(4-(3-(cyclohexyloxy)phenylthio)-2,3-bis(tri...)
Affinity DataIC50:  530nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265284((E)-3-(4-(3-((trans)-4-methylcyclohexyloxy)phenylt...)
Affinity DataIC50:  810nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265247((E)-3-(4-(3-((cis)-4-methylcyclohexyloxy)phenylthi...)
Affinity DataIC50:  860nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction (unknown origin) by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed