Compile Data Set for Download or QSAR
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Found 7 Enz. Inhib. hit(s) with all data for entry = 50030251
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50293183((R)-4-methyl-2-(2-(5-(quinoline-8-sulfonamido)-1H-...)
Affinity DataKi:  545nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cells after 60 mins by beta plate liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50293183((R)-4-methyl-2-(2-(5-(quinoline-8-sulfonamido)-1H-...)
Affinity DataIC50:  3.76nMAssay Description:Antagonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium elevation pretreated 30 mins befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50034787(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-meth...)
Affinity DataIC50:  3.79nMAssay Description:Antagonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium elevation pretreated 30 mins befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  6.03nMAssay Description:Antagonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium elevation pretreated 30 mins befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as increase in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50034787(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-meth...)
Affinity DataEC50:  2.16E+5nMAssay Description:Agonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as increase in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50293183((R)-4-methyl-2-(2-(5-(quinoline-8-sulfonamido)-1H-...)
Affinity DataEC50:  1.78E+5nMAssay Description:Agonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as increase in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed