Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50027474
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246540((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246541((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  0.890nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246483(3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2-pro...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM14392(3-ethyl-5-{5-[(4-ethylpiperazine-1-)sulfonyl]-2-(2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245798((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246538((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246539((R)-3-ethyl-5-(2-(1-methoxypropan-2-yloxy)-5-(4-pr...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246484(5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2-(2-methoxye...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245799((S)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245858((S)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245801((S)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245800((S)-3-ethyl-5-(2-(1-methoxypropan-2-yloxy)-5-(4-pr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245955((S)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50246541((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  734nMAssay Description:Inhibition of canine retina PDE6 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50246539((R)-3-ethyl-5-(2-(1-methoxypropan-2-yloxy)-5-(4-pr...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of canine retina PDE6 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50246540((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of canine retina PDE6 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50246538((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of canine retina PDE6 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50245798((R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2...)
Affinity DataIC50:  4.32E+3nMAssay Description:Inhibition of canine retina PDE6 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed