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PubMed code 18952440

Compile data set for download or QSAR
Found 49 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273767
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C151H226N40O46/c1-16-77(10)121(148(235)182-103(58-83-30-19-17-20-31-83)137(224)173-94-37-26-28-54-159-111(199)49-44-95(129(216)162-66-112(200)169-92(124(155)211)38-29-55-160-151(156)157)176-146(233)119(75(6)7)188-140(227)101(57-74(4)5)178-139(226)105(180-134(94)221)61-86-64-161-91-35-24-23-34-89(86)91)190-135(222)99(47-52-117(207)208)175-133(220)93(36-25-27-53-152)171-126(213)79(12)166-125(212)78(11)168-132(219)98(43-48-110(154)198)170-113(201)67-163-131(218)97(46-51-116(205)206)174-136(223)100(56-73(2)3)177-138(225)102(60-85-39-41-88(197)42-40-85)179-143(230)107(69-192)184-145(232)109(71-194)185-147(234)120(76(8)9)189-142(229)106(63-118(209)210)181-144(231)108(70-193)186-150(237)123(82(15)196)191-141(228)104(59-84-32-21-18-22-33-84)183-149(236)122(81(14)195)187-114(202)68-164-130(217)96(45-50-115(203)204)172-127(214)80(13)167-128(215)90(153)62-87-65-158-72-165-87/h17-24,30-35,39-42,64-65,72-82,90,92-109,119-123,161,192-197H,16,25-29,36-38,43-63,66-71,152-153H2,1-15H3,(H2,154,198)(H2,155,211)(H,158,165)(H,159,199)(H,162,216)(H,163,218)(H,164,217)(H,166,212)(H,167,215)(H,168,219)(H,169,200)(H,170,201)(H,171,213)(H,172,214)(H,173,224)(H,174,223)(H,175,220)(H,176,233)(H,177,225)(H,178,226)(H,179,230)(H,180,221)(H,181,231)(H,182,235)(H,183,236)(H,184,232)(H,185,234)(H,186,237)(H,187,202)(H,188,227)(H,189,229)(H,190,222)(H,191,228)(H,203,204)(H,205,206)(H,207,208)(H,209,210)(H4,156,157,160)/t77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273766
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C152H233N41O44/c1-18-79(10)122(149(235)184-105(60-87-34-21-19-22-35-87)137(223)171-83(14)129(215)179-108(63-90-66-163-95-39-26-25-38-93(90)95)140(226)181-104(59-76(4)5)141(227)190-120(77(6)7)147(233)178-97(40-27-30-54-153)131(217)164-68-114(202)172-96(125(157)211)43-33-57-162-152(158)159)192-136(222)102(48-51-113(156)201)177-135(221)99(41-28-31-55-154)174-127(213)81(12)168-126(212)80(11)170-134(220)98(42-29-32-56-161-86(17)199)173-115(203)69-165-133(219)101(50-53-118(207)208)176-138(224)103(58-75(2)3)180-139(225)106(62-89-44-46-92(200)47-45-89)182-144(230)110(71-194)186-146(232)112(73-196)187-148(234)121(78(8)9)191-143(229)109(65-119(209)210)183-145(231)111(72-195)188-151(237)124(85(16)198)193-142(228)107(61-88-36-23-20-24-37-88)185-150(236)123(84(15)197)189-116(204)70-166-132(218)100(49-52-117(205)206)175-128(214)82(13)169-130(216)94(155)64-91-67-160-74-167-91/h19-26,34-39,44-47,66-67,74-85,94,96-112,120-124,163,194-198,200H,18,27-33,40-43,48-65,68-73,153-155H2,1-17H3,(H2,156,201)(H2,157,211)(H,160,167)(H,161,199)(H,164,217)(H,165,219)(H,166,218)(H,168,212)(H,169,216)(H,170,220)(H,171,223)(H,172,202)(H,173,203)(H,174,213)(H,175,214)(H,176,224)(H,177,221)(H,178,233)(H,179,215)(H,180,225)(H,181,226)(H,182,230)(H,183,231)(H,184,235)(H,185,236)(H,186,232)(H,187,234)(H,188,237)(H,189,204)(H,190,227)(H,191,229)(H,192,222)(H,193,228)(H,205,206)(H,207,208)(H,209,210)(H4,158,159,162)/t79-,80-,81-,82-,83-,84+,85+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,120-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273752
PNG
(CHEMBL503836 | HAEGTFTSDVSSYLEGQAAKEIFAWLVKGR)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1S/C149H225N39O46/c1-17-76(10)119(145(230)179-101(57-83-31-20-18-21-32-83)133(218)166-80(14)125(210)174-104(60-86-63-158-91-36-25-24-35-89(86)91)136(221)176-100(56-73(4)5)137(222)185-117(74(6)7)143(228)173-92(37-26-28-52-150)127(212)159-66-111(197)168-98(148(233)234)39-30-54-157-149(154)155)187-132(217)97(47-51-115(203)204)172-131(216)93(38-27-29-53-151)169-123(208)78(12)163-122(207)77(11)165-130(215)96(44-48-109(153)195)167-110(196)65-160-129(214)95(46-50-114(201)202)171-134(219)99(55-72(2)3)175-135(220)102(59-85-40-42-88(194)43-41-85)177-140(225)106(68-189)181-142(227)108(70-191)182-144(229)118(75(8)9)186-139(224)105(62-116(205)206)178-141(226)107(69-190)183-147(232)121(82(16)193)188-138(223)103(58-84-33-22-19-23-34-84)180-146(231)120(81(15)192)184-112(198)67-161-128(213)94(45-49-113(199)200)170-124(209)79(13)164-126(211)90(152)61-87-64-156-71-162-87/h18-25,31-36,40-43,63-64,71-82,90,92-108,117-121,158,189-194H,17,26-30,37-39,44-62,65-70,150-152H2,1-16H3,(H2,153,195)(H,156,162)(H,159,212)(H,160,214)(H,161,213)(H,163,207)(H,164,211)(H,165,215)(H,166,218)(H,167,196)(H,168,197)(H,169,208)(H,170,209)(H,171,219)(H,172,216)(H,173,228)(H,174,210)(H,175,220)(H,176,221)(H,177,225)(H,178,226)(H,179,230)(H,180,231)(H,181,227)(H,182,229)(H,183,232)(H,184,198)(H,185,222)(H,186,224)(H,187,217)(H,188,223)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H,233,234)(H4,154,155,157)/t76-,77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,117-,118-,119-,120-,121-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273766
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C152H233N41O44/c1-18-79(10)122(149(235)184-105(60-87-34-21-19-22-35-87)137(223)171-83(14)129(215)179-108(63-90-66-163-95-39-26-25-38-93(90)95)140(226)181-104(59-76(4)5)141(227)190-120(77(6)7)147(233)178-97(40-27-30-54-153)131(217)164-68-114(202)172-96(125(157)211)43-33-57-162-152(158)159)192-136(222)102(48-51-113(156)201)177-135(221)99(41-28-31-55-154)174-127(213)81(12)168-126(212)80(11)170-134(220)98(42-29-32-56-161-86(17)199)173-115(203)69-165-133(219)101(50-53-118(207)208)176-138(224)103(58-75(2)3)180-139(225)106(62-89-44-46-92(200)47-45-89)182-144(230)110(71-194)186-146(232)112(73-196)187-148(234)121(78(8)9)191-143(229)109(65-119(209)210)183-145(231)111(72-195)188-151(237)124(85(16)198)193-142(228)107(61-88-36-23-20-24-37-88)185-150(236)123(84(15)197)189-116(204)70-166-132(218)100(49-52-117(205)206)175-128(214)82(13)169-130(216)94(155)64-91-67-160-74-167-91/h19-26,34-39,44-47,66-67,74-85,94,96-112,120-124,163,194-198,200H,18,27-33,40-43,48-65,68-73,153-155H2,1-17H3,(H2,156,201)(H2,157,211)(H,160,167)(H,161,199)(H,164,217)(H,165,219)(H,166,218)(H,168,212)(H,169,216)(H,170,220)(H,171,223)(H,172,202)(H,173,203)(H,174,213)(H,175,214)(H,176,224)(H,177,221)(H,178,233)(H,179,215)(H,180,225)(H,181,226)(H,182,230)(H,183,231)(H,184,235)(H,185,236)(H,186,232)(H,187,234)(H,188,237)(H,189,204)(H,190,227)(H,191,229)(H,192,222)(H,193,228)(H,205,206)(H,207,208)(H,209,210)(H4,158,159,162)/t79-,80-,81-,82-,83-,84+,85+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,120-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273752
PNG
(CHEMBL503836 | HAEGTFTSDVSSYLEGQAAKEIFAWLVKGR)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1S/C149H225N39O46/c1-17-76(10)119(145(230)179-101(57-83-31-20-18-21-32-83)133(218)166-80(14)125(210)174-104(60-86-63-158-91-36-25-24-35-89(86)91)136(221)176-100(56-73(4)5)137(222)185-117(74(6)7)143(228)173-92(37-26-28-52-150)127(212)159-66-111(197)168-98(148(233)234)39-30-54-157-149(154)155)187-132(217)97(47-51-115(203)204)172-131(216)93(38-27-29-53-151)169-123(208)78(12)163-122(207)77(11)165-130(215)96(44-48-109(153)195)167-110(196)65-160-129(214)95(46-50-114(201)202)171-134(219)99(55-72(2)3)175-135(220)102(59-85-40-42-88(194)43-41-85)177-140(225)106(68-189)181-142(227)108(70-191)182-144(229)118(75(8)9)186-139(224)105(62-116(205)206)178-141(226)107(69-190)183-147(232)121(82(16)193)188-138(223)103(58-84-33-22-19-23-34-84)180-146(231)120(81(15)192)184-112(198)67-161-128(213)94(45-49-113(199)200)170-124(209)79(13)164-126(211)90(152)61-87-64-156-71-162-87/h18-25,31-36,40-43,63-64,71-82,90,92-108,117-121,158,189-194H,17,26-30,37-39,44-62,65-70,150-152H2,1-16H3,(H2,153,195)(H,156,162)(H,159,212)(H,160,214)(H,161,213)(H,163,207)(H,164,211)(H,165,215)(H,166,218)(H,167,196)(H,168,197)(H,169,208)(H,170,209)(H,171,219)(H,172,216)(H,173,228)(H,174,210)(H,175,220)(H,176,221)(H,177,225)(H,178,226)(H,179,230)(H,180,231)(H,181,227)(H,182,229)(H,183,232)(H,184,198)(H,185,222)(H,186,224)(H,187,217)(H,188,223)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H,233,234)(H4,154,155,157)/t76-,77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,117-,118-,119-,120-,121-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273765
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C150H228N40O43/c1-17-78(10)120(147(231)181-103(59-85-33-20-18-21-34-85)135(219)168-82(14)127(211)176-106(62-88-65-160-93-38-25-24-37-91(88)93)138(222)178-102(58-75(4)5)139(223)187-118(76(6)7)145(229)175-95(39-26-29-53-151)129(213)161-67-112(198)169-94(123(154)207)42-32-56-159-150(155)156)189-134(218)100-47-50-111(197)158-55-31-28-41-96(132(216)167-79(11)124(208)165-80(12)125(209)171-97(133(217)174-100)40-27-30-54-152)170-113(199)68-162-131(215)99(49-52-116(203)204)173-136(220)101(57-74(2)3)177-137(221)104(61-87-43-45-90(196)46-44-87)179-142(226)108(70-191)183-144(228)110(72-193)184-146(230)119(77(8)9)188-141(225)107(64-117(205)206)180-143(227)109(71-192)185-149(233)122(84(16)195)190-140(224)105(60-86-35-22-19-23-36-86)182-148(232)121(83(15)194)186-114(200)69-163-130(214)98(48-51-115(201)202)172-126(210)81(13)166-128(212)92(153)63-89-66-157-73-164-89/h18-25,33-38,43-46,65-66,73-84,92,94-110,118-122,160,191-196H,17,26-32,39-42,47-64,67-72,151-153H2,1-16H3,(H2,154,207)(H,157,164)(H,158,197)(H,161,213)(H,162,215)(H,163,214)(H,165,208)(H,166,212)(H,167,216)(H,168,219)(H,169,198)(H,170,199)(H,171,209)(H,172,210)(H,173,220)(H,174,217)(H,175,229)(H,176,211)(H,177,221)(H,178,222)(H,179,226)(H,180,227)(H,181,231)(H,182,232)(H,183,228)(H,184,230)(H,185,233)(H,186,200)(H,187,223)(H,188,225)(H,189,218)(H,190,224)(H,201,202)(H,203,204)(H,205,206)(H4,155,156,159)/t78-,79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,120-,121-,122-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273765
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C150H228N40O43/c1-17-78(10)120(147(231)181-103(59-85-33-20-18-21-34-85)135(219)168-82(14)127(211)176-106(62-88-65-160-93-38-25-24-37-91(88)93)138(222)178-102(58-75(4)5)139(223)187-118(76(6)7)145(229)175-95(39-26-29-53-151)129(213)161-67-112(198)169-94(123(154)207)42-32-56-159-150(155)156)189-134(218)100-47-50-111(197)158-55-31-28-41-96(132(216)167-79(11)124(208)165-80(12)125(209)171-97(133(217)174-100)40-27-30-54-152)170-113(199)68-162-131(215)99(49-52-116(203)204)173-136(220)101(57-74(2)3)177-137(221)104(61-87-43-45-90(196)46-44-87)179-142(226)108(70-191)183-144(228)110(72-193)184-146(230)119(77(8)9)188-141(225)107(64-117(205)206)180-143(227)109(71-192)185-149(233)122(84(16)195)190-140(224)105(60-86-35-22-19-23-36-86)182-148(232)121(83(15)194)186-114(200)69-163-130(214)98(48-51-115(201)202)172-126(210)81(13)166-128(212)92(153)63-89-66-157-73-164-89/h18-25,33-38,43-46,65-66,73-84,92,94-110,118-122,160,191-196H,17,26-32,39-42,47-64,67-72,151-153H2,1-16H3,(H2,154,207)(H,157,164)(H,158,197)(H,161,213)(H,162,215)(H,163,214)(H,165,208)(H,166,212)(H,167,216)(H,168,219)(H,169,198)(H,170,199)(H,171,209)(H,172,210)(H,173,220)(H,174,217)(H,175,229)(H,176,211)(H,177,221)(H,178,222)(H,179,226)(H,180,227)(H,181,231)(H,182,232)(H,183,228)(H,184,230)(H,185,233)(H,186,200)(H,187,223)(H,188,225)(H,189,218)(H,190,224)(H,201,202)(H,203,204)(H,205,206)(H4,155,156,159)/t78-,79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,120-,121-,122-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273757
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C149H223N41O46/c1-13-75(6)119(146(234)182-101(58-82-29-16-14-17-30-82)136(224)168-79(10)126(214)178-104(61-85-64-160-90-34-21-20-33-88(85)90)138(226)179-100(57-73(2)3)140(228)188-118(74(4)5)145(233)177-92(35-22-25-53-150)128(216)161-66-111(199)169-91(122(154)210)38-28-56-159-149(155)156)189-135(223)99(47-52-116(206)207)175-132(220)93(36-23-26-54-151)171-124(212)77(8)165-123(211)76(7)167-131(219)97(43-48-109(153)197)170-112(200)67-162-130(218)96(46-51-115(204)205)174-134(222)98-44-49-110(198)158-55-27-24-37-94(133(221)184-107(70-192)144(232)185-106(69-191)142(230)180-102(137(225)176-98)60-84-39-41-87(196)42-40-84)173-139(227)105(63-117(208)209)181-143(231)108(71-193)186-148(236)121(81(12)195)190-141(229)103(59-83-31-18-15-19-32-83)183-147(235)120(80(11)194)187-113(201)68-163-129(217)95(45-50-114(202)203)172-125(213)78(9)166-127(215)89(152)62-86-65-157-72-164-86/h14-21,29-34,39-42,64-65,72-81,89,91-108,118-121,160,191-196H,13,22-28,35-38,43-63,66-71,150-152H2,1-12H3,(H2,153,197)(H2,154,210)(H,157,164)(H,158,198)(H,161,216)(H,162,218)(H,163,217)(H,165,211)(H,166,215)(H,167,219)(H,168,224)(H,169,199)(H,170,200)(H,171,212)(H,172,213)(H,173,227)(H,174,222)(H,175,220)(H,176,225)(H,177,233)(H,178,214)(H,179,226)(H,180,230)(H,181,231)(H,182,234)(H,183,235)(H,184,221)(H,185,232)(H,186,236)(H,187,201)(H,188,228)(H,189,223)(H,190,229)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H4,155,156,159)/t75-,76-,77-,78-,79-,80+,81+,89-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,118-,119-,120-,121-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.5n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273757
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C149H223N41O46/c1-13-75(6)119(146(234)182-101(58-82-29-16-14-17-30-82)136(224)168-79(10)126(214)178-104(61-85-64-160-90-34-21-20-33-88(85)90)138(226)179-100(57-73(2)3)140(228)188-118(74(4)5)145(233)177-92(35-22-25-53-150)128(216)161-66-111(199)169-91(122(154)210)38-28-56-159-149(155)156)189-135(223)99(47-52-116(206)207)175-132(220)93(36-23-26-54-151)171-124(212)77(8)165-123(211)76(7)167-131(219)97(43-48-109(153)197)170-112(200)67-162-130(218)96(46-51-115(204)205)174-134(222)98-44-49-110(198)158-55-27-24-37-94(133(221)184-107(70-192)144(232)185-106(69-191)142(230)180-102(137(225)176-98)60-84-39-41-87(196)42-40-84)173-139(227)105(63-117(208)209)181-143(231)108(71-193)186-148(236)121(81(12)195)190-141(229)103(59-83-31-18-15-19-32-83)183-147(235)120(80(11)194)187-113(201)68-163-129(217)95(45-50-114(202)203)172-125(213)78(9)166-127(215)89(152)62-86-65-157-72-164-86/h14-21,29-34,39-42,64-65,72-81,89,91-108,118-121,160,191-196H,13,22-28,35-38,43-63,66-71,150-152H2,1-12H3,(H2,153,197)(H2,154,210)(H,157,164)(H,158,198)(H,161,216)(H,162,218)(H,163,217)(H,165,211)(H,166,215)(H,167,219)(H,168,224)(H,169,199)(H,170,200)(H,171,212)(H,172,213)(H,173,227)(H,174,222)(H,175,220)(H,176,225)(H,177,233)(H,178,214)(H,179,226)(H,180,230)(H,181,231)(H,182,234)(H,183,235)(H,184,221)(H,185,232)(H,186,236)(H,187,201)(H,188,228)(H,189,223)(H,190,229)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H4,155,156,159)/t75-,76-,77-,78-,79-,80+,81+,89-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,118-,119-,120-,121-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.5n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273758
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C151H228N42O47/c1-14-76(6)121(148(238)185-103(59-84-30-17-15-18-31-84)138(228)171-80(10)128(218)181-106(62-87-65-163-92-35-22-21-34-90(87)92)140(230)182-102(58-74(2)3)142(232)191-120(75(4)5)147(237)180-94(36-23-26-54-152)130(220)164-67-113(203)172-93(124(157)214)39-29-57-162-151(158)159)192-137(227)101(48-53-118(210)211)178-134(224)95(37-24-27-55-153)174-126(216)78(8)168-125(215)77(7)170-133(223)99(44-49-111(155)201)173-114(204)68-165-132(222)98(47-52-117(208)209)177-136(226)100(45-50-112(156)202)179-139(229)104(61-86-40-42-89(200)43-41-86)183-144(234)108(70-194)188-146(236)109(71-195)187-135(225)96(38-25-28-56-161-83(13)199)176-141(231)107(64-119(212)213)184-145(235)110(72-196)189-150(240)123(82(12)198)193-143(233)105(60-85-32-19-16-20-33-85)186-149(239)122(81(11)197)190-115(205)69-166-131(221)97(46-51-116(206)207)175-127(217)79(9)169-129(219)91(154)63-88-66-160-73-167-88/h15-22,30-35,40-43,65-66,73-82,91,93-110,120-123,163,194-198,200H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,201)(H2,156,202)(H2,157,214)(H,160,167)(H,161,199)(H,164,220)(H,165,222)(H,166,221)(H,168,215)(H,169,219)(H,170,223)(H,171,228)(H,172,203)(H,173,204)(H,174,216)(H,175,217)(H,176,231)(H,177,226)(H,178,224)(H,179,229)(H,180,237)(H,181,218)(H,182,230)(H,183,234)(H,184,235)(H,185,238)(H,186,239)(H,187,225)(H,188,236)(H,189,240)(H,190,205)(H,191,232)(H,192,227)(H,193,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,158,159,162)/t76-,77-,78-,79-,80-,81+,82+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273758
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C151H228N42O47/c1-14-76(6)121(148(238)185-103(59-84-30-17-15-18-31-84)138(228)171-80(10)128(218)181-106(62-87-65-163-92-35-22-21-34-90(87)92)140(230)182-102(58-74(2)3)142(232)191-120(75(4)5)147(237)180-94(36-23-26-54-152)130(220)164-67-113(203)172-93(124(157)214)39-29-57-162-151(158)159)192-137(227)101(48-53-118(210)211)178-134(224)95(37-24-27-55-153)174-126(216)78(8)168-125(215)77(7)170-133(223)99(44-49-111(155)201)173-114(204)68-165-132(222)98(47-52-117(208)209)177-136(226)100(45-50-112(156)202)179-139(229)104(61-86-40-42-89(200)43-41-86)183-144(234)108(70-194)188-146(236)109(71-195)187-135(225)96(38-25-28-56-161-83(13)199)176-141(231)107(64-119(212)213)184-145(235)110(72-196)189-150(240)123(82(12)198)193-143(233)105(60-85-32-19-16-20-33-85)186-149(239)122(81(11)197)190-115(205)69-166-131(221)97(46-51-116(206)207)175-127(217)79(9)169-129(219)91(154)63-88-66-160-73-167-88/h15-22,30-35,40-43,65-66,73-82,91,93-110,120-123,163,194-198,200H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,201)(H2,156,202)(H2,157,214)(H,160,167)(H,161,199)(H,164,220)(H,165,222)(H,166,221)(H,168,215)(H,169,219)(H,170,223)(H,171,228)(H,172,203)(H,173,204)(H,174,216)(H,175,217)(H,176,231)(H,177,226)(H,178,224)(H,179,229)(H,180,237)(H,181,218)(H,182,230)(H,183,234)(H,184,235)(H,185,238)(H,186,239)(H,187,225)(H,188,236)(H,189,240)(H,190,205)(H,191,232)(H,192,227)(H,193,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,158,159,162)/t76-,77-,78-,79-,80-,81+,82+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273759
PNG
((3S,6S,9S,12S,15S,21S)-3-((S)-1-((S)-1-((2S,5S,8S,...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C155H235N41O45/c1-17-80(10)124(152(239)188-107(63-87-33-20-18-21-34-87)141(228)173-84(14)131(218)183-110(66-90-69-166-95-38-25-24-37-93(90)95)144(231)185-106(62-77(4)5)145(232)193-122(78(6)7)150(237)182-97(39-26-29-57-156)133(220)167-71-116(204)174-96(127(160)214)42-32-60-165-155(161)162)195-140(227)104(51-56-120(210)211)180-136(223)98(40-27-30-58-157)175-129(216)82(12)170-128(215)81(11)172-135(222)101(47-52-114(159)202)178-138(225)102-48-53-115(203)164-59-31-28-41-99(137(224)186-108(65-89-43-45-92(201)46-44-89)143(230)184-105(61-76(2)3)142(229)181-103(139(226)179-102)50-55-119(208)209)177-148(235)112(73-197)190-151(238)123(79(8)9)194-147(234)111(68-121(212)213)187-149(236)113(74-198)191-154(241)126(86(16)200)196-146(233)109(64-88-35-22-19-23-36-88)189-153(240)125(85(15)199)192-117(205)72-168-134(221)100(49-54-118(206)207)176-130(217)83(13)171-132(219)94(158)67-91-70-163-75-169-91/h18-25,33-38,43-46,69-70,75-86,94,96-113,122-126,166,197-201H,17,26-32,39-42,47-68,71-74,156-158H2,1-16H3,(H2,159,202)(H2,160,214)(H,163,169)(H,164,203)(H,167,220)(H,168,221)(H,170,215)(H,171,219)(H,172,222)(H,173,228)(H,174,204)(H,175,216)(H,176,217)(H,177,235)(H,178,225)(H,179,226)(H,180,223)(H,181,229)(H,182,237)(H,183,218)(H,184,230)(H,185,231)(H,186,224)(H,187,236)(H,188,239)(H,189,240)(H,190,238)(H,191,241)(H,192,205)(H,193,232)(H,194,234)(H,195,227)(H,196,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,161,162,165)/t80-,81-,82-,83-,84-,85+,86+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273760
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37S,40S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C157H240N42O46/c1-18-81(10)126(154(243)191-109(64-89-34-21-19-22-35-89)143(232)176-85(14)133(222)186-112(67-92-70-169-97-39-26-25-38-95(92)97)146(235)188-108(63-78(4)5)147(236)196-124(79(6)7)152(241)185-99(40-27-30-58-158)135(224)170-72-118(208)177-98(129(163)218)43-33-61-168-157(164)165)198-142(231)106(52-57-122(214)215)183-138(227)100(41-28-31-59-159)178-131(220)83(12)173-130(219)82(11)175-137(226)103(48-53-116(161)206)181-140(229)104(49-54-117(162)207)182-141(230)105(51-56-121(212)213)184-144(233)107(62-77(2)3)187-145(234)110(66-91-44-46-94(205)47-45-91)189-139(228)101(42-29-32-60-167-88(17)204)180-150(239)114(74-200)193-153(242)125(80(8)9)197-149(238)113(69-123(216)217)190-151(240)115(75-201)194-156(245)128(87(16)203)199-148(237)111(65-90-36-23-20-24-37-90)192-155(244)127(86(15)202)195-119(209)73-171-136(225)102(50-55-120(210)211)179-132(221)84(13)174-134(223)96(160)68-93-71-166-76-172-93/h19-26,34-39,44-47,70-71,76-87,96,98-115,124-128,169,200-203,205H,18,27-33,40-43,48-69,72-75,158-160H2,1-17H3,(H2,161,206)(H2,162,207)(H2,163,218)(H,166,172)(H,167,204)(H,170,224)(H,171,225)(H,173,219)(H,174,223)(H,175,226)(H,176,232)(H,177,208)(H,178,220)(H,179,221)(H,180,239)(H,181,229)(H,182,230)(H,183,227)(H,184,233)(H,185,241)(H,186,222)(H,187,234)(H,188,235)(H,189,228)(H,190,240)(H,191,243)(H,192,244)(H,193,242)(H,194,245)(H,195,209)(H,196,236)(H,197,238)(H,198,231)(H,199,237)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,168)/t81-,82-,83-,84-,85-,86+,87+,96-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,124-,125-,126-,127-,128-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273760
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37S,40S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C157H240N42O46/c1-18-81(10)126(154(243)191-109(64-89-34-21-19-22-35-89)143(232)176-85(14)133(222)186-112(67-92-70-169-97-39-26-25-38-95(92)97)146(235)188-108(63-78(4)5)147(236)196-124(79(6)7)152(241)185-99(40-27-30-58-158)135(224)170-72-118(208)177-98(129(163)218)43-33-61-168-157(164)165)198-142(231)106(52-57-122(214)215)183-138(227)100(41-28-31-59-159)178-131(220)83(12)173-130(219)82(11)175-137(226)103(48-53-116(161)206)181-140(229)104(49-54-117(162)207)182-141(230)105(51-56-121(212)213)184-144(233)107(62-77(2)3)187-145(234)110(66-91-44-46-94(205)47-45-91)189-139(228)101(42-29-32-60-167-88(17)204)180-150(239)114(74-200)193-153(242)125(80(8)9)197-149(238)113(69-123(216)217)190-151(240)115(75-201)194-156(245)128(87(16)203)199-148(237)111(65-90-36-23-20-24-37-90)192-155(244)127(86(15)202)195-119(209)73-171-136(225)102(50-55-120(210)211)179-132(221)84(13)174-134(223)96(160)68-93-71-166-76-172-93/h19-26,34-39,44-47,70-71,76-87,96,98-115,124-128,169,200-203,205H,18,27-33,40-43,48-69,72-75,158-160H2,1-17H3,(H2,161,206)(H2,162,207)(H2,163,218)(H,166,172)(H,167,204)(H,170,224)(H,171,225)(H,173,219)(H,174,223)(H,175,226)(H,176,232)(H,177,208)(H,178,220)(H,179,221)(H,180,239)(H,181,229)(H,182,230)(H,183,227)(H,184,233)(H,185,241)(H,186,222)(H,187,234)(H,188,235)(H,189,228)(H,190,240)(H,191,243)(H,192,244)(H,193,242)(H,194,245)(H,195,209)(H,196,236)(H,197,238)(H,198,231)(H,199,237)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,168)/t81-,82-,83-,84-,85-,86+,87+,96-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,124-,125-,126-,127-,128-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273753
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C152H231N41O43/c1-16-80(10)123(150(235)186-106(62-86-32-19-17-20-33-86)139(224)171-84(14)129(214)181-109(65-89-67-163-94-37-24-23-36-92(89)94)142(227)183-105(61-77(4)5)143(228)191-121(78(6)7)148(233)180-96(38-25-28-56-153)131(216)164-69-115(201)172-95(125(157)210)41-31-59-162-152(158)159)192-138(223)103(50-55-120(208)209)178-136(221)98(39-26-29-57-154)175-127(212)82(12)168-126(211)81(11)170-134(219)101(46-51-113(156)199)174-117(203)71-166-133(218)100(49-54-119(206)207)177-140(225)104(60-76(2)3)182-141(226)107(64-88-42-44-91(198)45-43-88)185-146(231)110(72-194)187-147(232)112(74-196)188-149(234)122(79(8)9)190-137(222)102-47-52-114(200)161-58-30-27-40-97(135(220)184-108(63-87-34-21-18-22-35-87)144(229)193-124(85(15)197)151(236)189-111(73-195)145(230)179-102)173-116(202)70-165-132(217)99(48-53-118(204)205)176-128(213)83(13)169-130(215)93(155)66-90-68-160-75-167-90/h17-24,32-37,42-45,67-68,75-85,93,95-112,121-124,163,194-198H,16,25-31,38-41,46-66,69-74,153-155H2,1-15H3,(H2,156,199)(H2,157,210)(H,160,167)(H,161,200)(H,164,216)(H,165,217)(H,166,218)(H,168,211)(H,169,215)(H,170,219)(H,171,224)(H,172,201)(H,173,202)(H,174,203)(H,175,212)(H,176,213)(H,177,225)(H,178,221)(H,179,230)(H,180,233)(H,181,214)(H,182,226)(H,183,227)(H,184,220)(H,185,231)(H,186,235)(H,187,232)(H,188,234)(H,189,236)(H,190,222)(H,191,228)(H,192,223)(H,193,229)(H,204,205)(H,206,207)(H,208,209)(H4,158,159,162)/t80-,81-,82-,83-,84-,85+,93-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 110n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273755
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C154H233N41O44/c1-17-80(10)124(151(237)188-107(63-87-33-20-18-21-34-87)141(227)173-84(14)131(217)183-110(66-90-69-165-95-38-25-24-37-93(90)95)144(230)185-106(62-77(4)5)145(231)192-122(78(6)7)149(235)181-97(39-26-29-57-155)133(219)166-71-115(202)174-96(127(159)213)42-32-60-164-154(160)161)194-140(226)104(51-56-120(209)210)179-137(223)98(40-27-30-58-156)176-129(215)82(12)170-128(214)81(11)172-136(222)102(47-52-113(158)200)175-116(203)72-167-135(221)101(50-55-119(207)208)178-142(228)105(61-76(2)3)184-143(229)108(65-89-43-45-92(199)46-44-89)186-139(225)103-48-53-114(201)163-59-31-28-41-99(138(224)187-111(68-121(211)212)147(233)193-123(79(8)9)150(236)190-112(74-196)148(234)180-103)182-153(239)126(86(16)198)195-146(232)109(64-88-35-22-19-23-36-88)189-152(238)125(85(15)197)191-117(204)73-168-134(220)100(49-54-118(205)206)177-130(216)83(13)171-132(218)94(157)67-91-70-162-75-169-91/h18-25,33-38,43-46,69-70,75-86,94,96-112,122-126,165,196-199H,17,26-32,39-42,47-68,71-74,155-157H2,1-16H3,(H2,158,200)(H2,159,213)(H,162,169)(H,163,201)(H,166,219)(H,167,221)(H,168,220)(H,170,214)(H,171,218)(H,172,222)(H,173,227)(H,174,202)(H,175,203)(H,176,215)(H,177,216)(H,178,228)(H,179,223)(H,180,234)(H,181,235)(H,182,239)(H,183,217)(H,184,229)(H,185,230)(H,186,225)(H,187,224)(H,188,237)(H,189,238)(H,190,236)(H,191,204)(H,192,231)(H,193,233)(H,194,226)(H,195,232)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H4,160,161,164)/t80-,81-,82-,83-,84-,85+,86+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 210n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273755
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C154H233N41O44/c1-17-80(10)124(151(237)188-107(63-87-33-20-18-21-34-87)141(227)173-84(14)131(217)183-110(66-90-69-165-95-38-25-24-37-93(90)95)144(230)185-106(62-77(4)5)145(231)192-122(78(6)7)149(235)181-97(39-26-29-57-155)133(219)166-71-115(202)174-96(127(159)213)42-32-60-164-154(160)161)194-140(226)104(51-56-120(209)210)179-137(223)98(40-27-30-58-156)176-129(215)82(12)170-128(214)81(11)172-136(222)102(47-52-113(158)200)175-116(203)72-167-135(221)101(50-55-119(207)208)178-142(228)105(61-76(2)3)184-143(229)108(65-89-43-45-92(199)46-44-89)186-139(225)103-48-53-114(201)163-59-31-28-41-99(138(224)187-111(68-121(211)212)147(233)193-123(79(8)9)150(236)190-112(74-196)148(234)180-103)182-153(239)126(86(16)198)195-146(232)109(64-88-35-22-19-23-36-88)189-152(238)125(85(15)197)191-117(204)73-168-134(220)100(49-54-118(205)206)177-130(216)83(13)171-132(218)94(157)67-91-70-162-75-169-91/h18-25,33-38,43-46,69-70,75-86,94,96-112,122-126,165,196-199H,17,26-32,39-42,47-68,71-74,155-157H2,1-16H3,(H2,158,200)(H2,159,213)(H,162,169)(H,163,201)(H,166,219)(H,167,221)(H,168,220)(H,170,214)(H,171,218)(H,172,222)(H,173,227)(H,174,202)(H,175,203)(H,176,215)(H,177,216)(H,178,228)(H,179,223)(H,180,234)(H,181,235)(H,182,239)(H,183,217)(H,184,229)(H,185,230)(H,186,225)(H,187,224)(H,188,237)(H,189,238)(H,190,236)(H,191,204)(H,192,231)(H,193,233)(H,194,226)(H,195,232)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H4,160,161,164)/t80-,81-,82-,83-,84-,85+,86+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 210n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273756
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C156H238N42O45/c1-18-81(10)126(153(241)191-109(64-89-34-21-19-22-35-89)143(231)176-85(14)133(221)186-112(67-92-70-168-97-39-26-25-38-95(92)97)146(234)188-108(63-78(4)5)147(235)195-124(79(6)7)151(239)184-99(40-27-30-58-157)135(223)169-72-117(206)177-98(129(162)217)43-33-61-167-156(163)164)197-142(230)106(52-57-122(213)214)182-139(227)100(41-28-31-59-158)179-131(219)83(12)173-130(218)82(11)175-138(226)104(48-53-115(160)204)178-118(207)73-170-137(225)103(51-56-121(211)212)181-144(232)107(62-77(2)3)187-145(233)110(66-91-44-46-94(203)47-45-91)189-141(229)105(49-54-116(161)205)183-150(238)114(75-199)193-152(240)125(80(8)9)196-149(237)113(69-123(215)216)190-140(228)101(42-29-32-60-166-88(17)202)185-155(243)128(87(16)201)198-148(236)111(65-90-36-23-20-24-37-90)192-154(242)127(86(15)200)194-119(208)74-171-136(224)102(50-55-120(209)210)180-132(220)84(13)174-134(222)96(159)68-93-71-165-76-172-93/h19-26,34-39,44-47,70-71,76-87,96,98-114,124-128,168,199-201,203H,18,27-33,40-43,48-69,72-75,157-159H2,1-17H3,(H2,160,204)(H2,161,205)(H2,162,217)(H,165,172)(H,166,202)(H,169,223)(H,170,225)(H,171,224)(H,173,218)(H,174,222)(H,175,226)(H,176,231)(H,177,206)(H,178,207)(H,179,219)(H,180,220)(H,181,232)(H,182,227)(H,183,238)(H,184,239)(H,185,243)(H,186,221)(H,187,233)(H,188,234)(H,189,229)(H,190,228)(H,191,241)(H,192,242)(H,193,240)(H,194,208)(H,195,235)(H,196,237)(H,197,230)(H,198,236)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,163,164,167)/t81-,82-,83-,84-,85-,86+,87+,96-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,124-,125-,126-,127-,128-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 229n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273754
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C154H236N42O44/c1-17-81(10)125(152(239)189-108(63-88-33-20-18-21-34-88)141(228)174-85(14)131(218)184-111(66-91-68-166-96-38-25-24-37-94(91)96)144(231)186-107(62-78(4)5)145(232)194-123(79(6)7)150(237)183-98(39-26-29-57-155)133(220)167-70-117(205)175-97(127(160)214)42-32-60-165-154(161)162)195-140(227)105(51-56-122(212)213)181-138(225)100(40-27-30-58-156)178-129(216)83(12)171-128(215)82(11)173-136(223)103(47-52-115(158)203)177-119(207)72-169-135(222)102(50-55-121(210)211)180-142(229)106(61-77(2)3)185-143(230)109(65-90-43-45-93(202)46-44-90)188-148(235)112(73-197)190-149(236)114(75-199)191-151(238)124(80(8)9)193-139(226)104(48-53-116(159)204)182-147(234)113(74-198)192-153(240)126(86(15)200)196-146(233)110(64-89-35-22-19-23-36-89)187-137(224)99(41-28-31-59-164-87(16)201)176-118(206)71-168-134(221)101(49-54-120(208)209)179-130(217)84(13)172-132(219)95(157)67-92-69-163-76-170-92/h18-25,33-38,43-46,68-69,76-86,95,97-114,123-126,166,197-200,202H,17,26-32,39-42,47-67,70-75,155-157H2,1-16H3,(H2,158,203)(H2,159,204)(H2,160,214)(H,163,170)(H,164,201)(H,167,220)(H,168,221)(H,169,222)(H,171,215)(H,172,219)(H,173,223)(H,174,228)(H,175,205)(H,176,206)(H,177,207)(H,178,216)(H,179,217)(H,180,229)(H,181,225)(H,182,234)(H,183,237)(H,184,218)(H,185,230)(H,186,231)(H,187,224)(H,188,235)(H,189,239)(H,190,236)(H,191,238)(H,192,240)(H,193,226)(H,194,232)(H,195,227)(H,196,233)(H,208,209)(H,210,211)(H,212,213)(H4,161,162,165)/t81-,82-,83-,84-,85-,86+,95-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 440n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273754
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C154H236N42O44/c1-17-81(10)125(152(239)189-108(63-88-33-20-18-21-34-88)141(228)174-85(14)131(218)184-111(66-91-68-166-96-38-25-24-37-94(91)96)144(231)186-107(62-78(4)5)145(232)194-123(79(6)7)150(237)183-98(39-26-29-57-155)133(220)167-70-117(205)175-97(127(160)214)42-32-60-165-154(161)162)195-140(227)105(51-56-122(212)213)181-138(225)100(40-27-30-58-156)178-129(216)83(12)171-128(215)82(11)173-136(223)103(47-52-115(158)203)177-119(207)72-169-135(222)102(50-55-121(210)211)180-142(229)106(61-77(2)3)185-143(230)109(65-90-43-45-93(202)46-44-90)188-148(235)112(73-197)190-149(236)114(75-199)191-151(238)124(80(8)9)193-139(226)104(48-53-116(159)204)182-147(234)113(74-198)192-153(240)126(86(15)200)196-146(233)110(64-89-35-22-19-23-36-89)187-137(224)99(41-28-31-59-164-87(16)201)176-118(206)71-168-134(221)101(49-54-120(208)209)179-130(217)84(13)172-132(219)95(157)67-92-69-163-76-170-92/h18-25,33-38,43-46,68-69,76-86,95,97-114,123-126,166,197-200,202H,17,26-32,39-42,47-67,70-75,155-157H2,1-16H3,(H2,158,203)(H2,159,204)(H2,160,214)(H,163,170)(H,164,201)(H,167,220)(H,168,221)(H,169,222)(H,171,215)(H,172,219)(H,173,223)(H,174,228)(H,175,205)(H,176,206)(H,177,207)(H,178,216)(H,179,217)(H,180,229)(H,181,225)(H,182,234)(H,183,237)(H,184,218)(H,185,230)(H,186,231)(H,187,224)(H,188,235)(H,189,239)(H,190,236)(H,191,238)(H,192,240)(H,193,226)(H,194,232)(H,195,227)(H,196,233)(H,208,209)(H,210,211)(H,212,213)(H4,161,162,165)/t81-,82-,83-,84-,85-,86+,95-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 440n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273762
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C153H232N42O47/c1-15-78(8)123(150(240)186-104(60-85-31-18-16-19-32-85)139(229)172-81(11)129(219)182-107(63-88-66-165-93-36-23-22-35-91(88)93)141(231)183-103(59-75(2)3)142(232)192-121(76(4)5)148(238)181-95(37-24-27-55-154)131(221)166-68-114(205)173-94(126(159)216)40-30-58-164-153(160)161)194-138(228)102(49-54-119(212)213)180-135(225)96(38-25-28-56-155)175-128(218)80(10)171-134(224)101(46-51-113(158)204)179-137(227)100(45-50-112(157)203)174-115(206)69-167-133(223)99(48-53-118(210)211)178-136(226)97(39-26-29-57-163-84(14)201)177-140(230)105(62-87-41-43-90(202)44-42-87)184-145(235)109(71-196)188-147(237)111(73-198)189-149(239)122(77(6)7)193-144(234)108(65-120(214)215)185-146(236)110(72-197)190-152(242)125(83(13)200)195-143(233)106(61-86-33-20-17-21-34-86)187-151(241)124(82(12)199)191-116(207)70-168-132(222)98(47-52-117(208)209)176-127(217)79(9)170-130(220)92(156)64-89-67-162-74-169-89/h16-23,31-36,41-44,66-67,74-83,92,94-111,121-125,165,196-200,202H,15,24-30,37-40,45-65,68-73,154-156H2,1-14H3,(H2,157,203)(H2,158,204)(H2,159,216)(H,162,169)(H,163,201)(H,166,221)(H,167,223)(H,168,222)(H,170,220)(H,171,224)(H,172,229)(H,173,205)(H,174,206)(H,175,218)(H,176,217)(H,177,230)(H,178,226)(H,179,227)(H,180,225)(H,181,238)(H,182,219)(H,183,231)(H,184,235)(H,185,236)(H,186,240)(H,187,241)(H,188,237)(H,189,239)(H,190,242)(H,191,207)(H,192,232)(H,193,234)(H,194,228)(H,195,233)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H4,160,161,164)/t78-,79-,80-,81-,82+,83+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,121-,122-,123-,124-,125-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273762
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C153H232N42O47/c1-15-78(8)123(150(240)186-104(60-85-31-18-16-19-32-85)139(229)172-81(11)129(219)182-107(63-88-66-165-93-36-23-22-35-91(88)93)141(231)183-103(59-75(2)3)142(232)192-121(76(4)5)148(238)181-95(37-24-27-55-154)131(221)166-68-114(205)173-94(126(159)216)40-30-58-164-153(160)161)194-138(228)102(49-54-119(212)213)180-135(225)96(38-25-28-56-155)175-128(218)80(10)171-134(224)101(46-51-113(158)204)179-137(227)100(45-50-112(157)203)174-115(206)69-167-133(223)99(48-53-118(210)211)178-136(226)97(39-26-29-57-163-84(14)201)177-140(230)105(62-87-41-43-90(202)44-42-87)184-145(235)109(71-196)188-147(237)111(73-198)189-149(239)122(77(6)7)193-144(234)108(65-120(214)215)185-146(236)110(72-197)190-152(242)125(83(13)200)195-143(233)106(61-86-33-20-17-21-34-86)187-151(241)124(82(12)199)191-116(207)70-168-132(222)98(47-52-117(208)209)176-127(217)79(9)170-130(220)92(156)64-89-67-162-74-169-89/h16-23,31-36,41-44,66-67,74-83,92,94-111,121-125,165,196-200,202H,15,24-30,37-40,45-65,68-73,154-156H2,1-14H3,(H2,157,203)(H2,158,204)(H2,159,216)(H,162,169)(H,163,201)(H,166,221)(H,167,223)(H,168,222)(H,170,220)(H,171,224)(H,172,229)(H,173,205)(H,174,206)(H,175,218)(H,176,217)(H,177,230)(H,178,226)(H,179,227)(H,180,225)(H,181,238)(H,182,219)(H,183,231)(H,184,235)(H,185,236)(H,186,240)(H,187,241)(H,188,237)(H,189,239)(H,190,242)(H,191,207)(H,192,232)(H,193,234)(H,194,228)(H,195,233)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H4,160,161,164)/t78-,79-,80-,81-,82+,83+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,121-,122-,123-,124-,125-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273764
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C154H236N42O45/c1-17-80(10)124(151(239)187-106(61-87-33-20-18-21-34-87)139(227)173-83(13)130(218)182-109(64-90-67-166-95-38-25-24-37-93(90)95)142(230)184-105(60-77(4)5)143(231)193-122(78(6)7)149(237)181-98(39-26-29-55-155)133(221)167-69-116(206)174-96(127(160)215)42-32-58-165-154(161)162)195-138(226)103(50-54-120(211)212)180-136(224)99(40-27-30-56-156)179-137(225)102(48-52-115(159)205)177-129(217)82(12)172-135(223)101(47-51-114(158)204)175-117(207)70-168-132(220)97(41-28-31-57-164-86(16)202)178-140(228)104(59-76(2)3)183-141(229)107(63-89-43-45-92(203)46-44-89)185-146(234)111(72-197)189-148(236)113(74-199)190-150(238)123(79(8)9)194-145(233)110(66-121(213)214)186-147(235)112(73-198)191-153(241)126(85(15)201)196-144(232)108(62-88-35-22-19-23-36-88)188-152(240)125(84(14)200)192-118(208)71-169-134(222)100(49-53-119(209)210)176-128(216)81(11)171-131(219)94(157)65-91-68-163-75-170-91/h18-25,33-38,43-46,67-68,75-85,94,96-113,122-126,166,197-201,203H,17,26-32,39-42,47-66,69-74,155-157H2,1-16H3,(H2,158,204)(H2,159,205)(H2,160,215)(H,163,170)(H,164,202)(H,167,221)(H,168,220)(H,169,222)(H,171,219)(H,172,223)(H,173,227)(H,174,206)(H,175,207)(H,176,216)(H,177,217)(H,178,228)(H,179,225)(H,180,224)(H,181,237)(H,182,218)(H,183,229)(H,184,230)(H,185,234)(H,186,235)(H,187,239)(H,188,240)(H,189,236)(H,190,238)(H,191,241)(H,192,208)(H,193,231)(H,194,233)(H,195,226)(H,196,232)(H,209,210)(H,211,212)(H,213,214)(H4,161,162,165)/t80-,81-,82-,83-,84+,85+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273764
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C154H236N42O45/c1-17-80(10)124(151(239)187-106(61-87-33-20-18-21-34-87)139(227)173-83(13)130(218)182-109(64-90-67-166-95-38-25-24-37-93(90)95)142(230)184-105(60-77(4)5)143(231)193-122(78(6)7)149(237)181-98(39-26-29-55-155)133(221)167-69-116(206)174-96(127(160)215)42-32-58-165-154(161)162)195-138(226)103(50-54-120(211)212)180-136(224)99(40-27-30-56-156)179-137(225)102(48-52-115(159)205)177-129(217)82(12)172-135(223)101(47-51-114(158)204)175-117(207)70-168-132(220)97(41-28-31-57-164-86(16)202)178-140(228)104(59-76(2)3)183-141(229)107(63-89-43-45-92(203)46-44-89)185-146(234)111(72-197)189-148(236)113(74-199)190-150(238)123(79(8)9)194-145(233)110(66-121(213)214)186-147(235)112(73-198)191-153(241)126(85(15)201)196-144(232)108(62-88-35-22-19-23-36-88)188-152(240)125(84(14)200)192-118(208)71-169-134(222)100(49-53-119(209)210)176-128(216)81(11)171-131(219)94(157)65-91-68-163-75-170-91/h18-25,33-38,43-46,67-68,75-85,94,96-113,122-126,166,197-201,203H,17,26-32,39-42,47-66,69-74,155-157H2,1-16H3,(H2,158,204)(H2,159,205)(H2,160,215)(H,163,170)(H,164,202)(H,167,221)(H,168,220)(H,169,222)(H,171,219)(H,172,223)(H,173,227)(H,174,206)(H,175,207)(H,176,216)(H,177,217)(H,178,228)(H,179,225)(H,180,224)(H,181,237)(H,182,218)(H,183,229)(H,184,230)(H,185,234)(H,186,235)(H,187,239)(H,188,240)(H,189,236)(H,190,238)(H,191,241)(H,192,208)(H,193,231)(H,194,233)(H,195,226)(H,196,232)(H,209,210)(H,211,212)(H,213,214)(H4,161,162,165)/t80-,81-,82-,83-,84+,85+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273761
PNG
((3S,6S,9S,12S,15S,21S)-3-((S)-1-((S)-1-((S)-1-((S)...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C151H227N41O46/c1-14-77(8)121(148(236)183-102(59-83-30-17-15-18-31-83)137(225)169-80(11)127(215)179-105(62-86-65-162-91-35-22-21-34-89(86)91)139(227)180-101(58-74(2)3)140(228)189-119(75(4)5)146(234)178-93(36-23-26-54-152)129(217)163-67-112(201)170-92(124(156)212)39-29-57-161-151(157)158)191-136(224)100(48-53-117(208)209)177-133(221)94(37-24-27-55-153)172-126(214)79(10)168-132(220)99-45-50-111(200)160-56-28-25-38-95(134(222)175-97(47-52-116(206)207)131(219)164-68-113(202)171-98(135(223)176-99)44-49-110(155)199)174-138(226)103(61-85-40-42-88(198)43-41-85)181-143(231)107(70-193)185-145(233)109(72-195)186-147(235)120(76(6)7)190-142(230)106(64-118(210)211)182-144(232)108(71-194)187-150(238)123(82(13)197)192-141(229)104(60-84-32-19-16-20-33-84)184-149(237)122(81(12)196)188-114(203)69-165-130(218)96(46-51-115(204)205)173-125(213)78(9)167-128(216)90(154)63-87-66-159-73-166-87/h15-22,30-35,40-43,65-66,73-82,90,92-109,119-123,162,193-198H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,199)(H2,156,212)(H,159,166)(H,160,200)(H,163,217)(H,164,219)(H,165,218)(H,167,216)(H,168,220)(H,169,225)(H,170,201)(H,171,202)(H,172,214)(H,173,213)(H,174,226)(H,175,222)(H,176,223)(H,177,221)(H,178,234)(H,179,215)(H,180,227)(H,181,231)(H,182,232)(H,183,236)(H,184,237)(H,185,233)(H,186,235)(H,187,238)(H,188,203)(H,189,228)(H,190,230)(H,191,224)(H,192,229)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H4,157,158,161)/t77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273761
PNG
((3S,6S,9S,12S,15S,21S)-3-((S)-1-((S)-1-((S)-1-((S)...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C151H227N41O46/c1-14-77(8)121(148(236)183-102(59-83-30-17-15-18-31-83)137(225)169-80(11)127(215)179-105(62-86-65-162-91-35-22-21-34-89(86)91)139(227)180-101(58-74(2)3)140(228)189-119(75(4)5)146(234)178-93(36-23-26-54-152)129(217)163-67-112(201)170-92(124(156)212)39-29-57-161-151(157)158)191-136(224)100(48-53-117(208)209)177-133(221)94(37-24-27-55-153)172-126(214)79(10)168-132(220)99-45-50-111(200)160-56-28-25-38-95(134(222)175-97(47-52-116(206)207)131(219)164-68-113(202)171-98(135(223)176-99)44-49-110(155)199)174-138(226)103(61-85-40-42-88(198)43-41-85)181-143(231)107(70-193)185-145(233)109(72-195)186-147(235)120(76(6)7)190-142(230)106(64-118(210)211)182-144(232)108(71-194)187-150(238)123(82(13)197)192-141(229)104(60-84-32-19-16-20-33-84)184-149(237)122(81(12)196)188-114(203)69-165-130(218)96(46-51-115(204)205)173-125(213)78(9)167-128(216)90(154)63-87-66-159-73-166-87/h15-22,30-35,40-43,65-66,73-82,90,92-109,119-123,162,193-198H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,199)(H2,156,212)(H,159,166)(H,160,200)(H,163,217)(H,164,219)(H,165,218)(H,167,216)(H,168,220)(H,169,225)(H,170,201)(H,171,202)(H,172,214)(H,173,213)(H,174,226)(H,175,222)(H,176,223)(H,177,221)(H,178,234)(H,179,215)(H,180,227)(H,181,231)(H,182,232)(H,183,236)(H,184,237)(H,185,233)(H,186,235)(H,187,238)(H,188,203)(H,189,228)(H,190,230)(H,191,224)(H,192,229)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H4,157,158,161)/t77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273763
PNG
((3S,6S,9S,12S,15S,21S)-3-((3S,6S,9S,12S,15S)-15-((...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C152H231N41O44/c1-16-79(10)122(149(235)184-104(60-85-32-19-17-20-33-85)137(223)170-82(13)128(214)179-107(63-88-66-163-93-37-24-23-36-91(88)93)140(226)181-103(59-76(4)5)141(227)190-120(77(6)7)147(233)178-96(38-25-28-54-153)131(217)164-68-114(202)171-94(125(157)211)41-31-57-162-152(158)159)192-136(222)101(49-53-118(207)208)177-134(220)97(39-26-29-55-154)176-135(221)100-47-51-113(201)161-56-30-27-40-95(130(216)165-69-115(203)172-99(46-50-112(156)200)133(219)169-81(12)127(213)174-100)175-138(224)102(58-75(2)3)180-139(225)105(62-87-42-44-90(199)45-43-87)182-144(230)109(71-194)186-146(232)111(73-196)187-148(234)121(78(8)9)191-143(229)108(65-119(209)210)183-145(231)110(72-195)188-151(237)124(84(15)198)193-142(228)106(61-86-34-21-18-22-35-86)185-150(236)123(83(14)197)189-116(204)70-166-132(218)98(48-52-117(205)206)173-126(212)80(11)168-129(215)92(155)64-89-67-160-74-167-89/h17-24,32-37,42-45,66-67,74-84,92,94-111,120-124,163,194-199H,16,25-31,38-41,46-65,68-73,153-155H2,1-15H3,(H2,156,200)(H2,157,211)(H,160,167)(H,161,201)(H,164,217)(H,165,216)(H,166,218)(H,168,215)(H,169,219)(H,170,223)(H,171,202)(H,172,203)(H,173,212)(H,174,213)(H,175,224)(H,176,221)(H,177,220)(H,178,233)(H,179,214)(H,180,225)(H,181,226)(H,182,230)(H,183,231)(H,184,235)(H,185,236)(H,186,232)(H,187,234)(H,188,237)(H,189,204)(H,190,227)(H,191,229)(H,192,222)(H,193,228)(H,205,206)(H,207,208)(H,209,210)(H4,158,159,162)/t79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.20E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273763
PNG
((3S,6S,9S,12S,15S,21S)-3-((3S,6S,9S,12S,15S)-15-((...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C152H231N41O44/c1-16-79(10)122(149(235)184-104(60-85-32-19-17-20-33-85)137(223)170-82(13)128(214)179-107(63-88-66-163-93-37-24-23-36-91(88)93)140(226)181-103(59-76(4)5)141(227)190-120(77(6)7)147(233)178-96(38-25-28-54-153)131(217)164-68-114(202)171-94(125(157)211)41-31-57-162-152(158)159)192-136(222)101(49-53-118(207)208)177-134(220)97(39-26-29-55-154)176-135(221)100-47-51-113(201)161-56-30-27-40-95(130(216)165-69-115(203)172-99(46-50-112(156)200)133(219)169-81(12)127(213)174-100)175-138(224)102(58-75(2)3)180-139(225)105(62-87-42-44-90(199)45-43-87)182-144(230)109(71-194)186-146(232)111(73-196)187-148(234)121(78(8)9)191-143(229)108(65-119(209)210)183-145(231)110(72-195)188-151(237)124(84(15)198)193-142(228)106(61-86-34-21-18-22-35-86)185-150(236)123(83(14)197)189-116(204)70-166-132(218)98(48-52-117(205)206)173-126(212)80(11)168-129(215)92(155)64-89-67-160-74-167-89/h17-24,32-37,42-45,66-67,74-84,92,94-111,120-124,163,194-199H,16,25-31,38-41,46-65,68-73,153-155H2,1-15H3,(H2,156,200)(H2,157,211)(H,160,167)(H,161,201)(H,164,217)(H,165,216)(H,166,218)(H,168,215)(H,169,219)(H,170,223)(H,171,202)(H,172,203)(H,173,212)(H,174,213)(H,175,224)(H,176,221)(H,177,220)(H,178,233)(H,179,214)(H,180,225)(H,181,226)(H,182,230)(H,183,231)(H,184,235)(H,185,236)(H,186,232)(H,187,234)(H,188,237)(H,189,204)(H,190,227)(H,191,229)(H,192,222)(H,193,228)(H,205,206)(H,207,208)(H,209,210)(H4,158,159,162)/t79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.20E+3n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273758
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C151H228N42O47/c1-14-76(6)121(148(238)185-103(59-84-30-17-15-18-31-84)138(228)171-80(10)128(218)181-106(62-87-65-163-92-35-22-21-34-90(87)92)140(230)182-102(58-74(2)3)142(232)191-120(75(4)5)147(237)180-94(36-23-26-54-152)130(220)164-67-113(203)172-93(124(157)214)39-29-57-162-151(158)159)192-137(227)101(48-53-118(210)211)178-134(224)95(37-24-27-55-153)174-126(216)78(8)168-125(215)77(7)170-133(223)99(44-49-111(155)201)173-114(204)68-165-132(222)98(47-52-117(208)209)177-136(226)100(45-50-112(156)202)179-139(229)104(61-86-40-42-89(200)43-41-86)183-144(234)108(70-194)188-146(236)109(71-195)187-135(225)96(38-25-28-56-161-83(13)199)176-141(231)107(64-119(212)213)184-145(235)110(72-196)189-150(240)123(82(12)198)193-143(233)105(60-85-32-19-16-20-33-85)186-149(239)122(81(11)197)190-115(205)69-166-131(221)97(46-51-116(206)207)175-127(217)79(9)169-129(219)91(154)63-88-66-160-73-167-88/h15-22,30-35,40-43,65-66,73-82,91,93-110,120-123,163,194-198,200H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,201)(H2,156,202)(H2,157,214)(H,160,167)(H,161,199)(H,164,220)(H,165,222)(H,166,221)(H,168,215)(H,169,219)(H,170,223)(H,171,228)(H,172,203)(H,173,204)(H,174,216)(H,175,217)(H,176,231)(H,177,226)(H,178,224)(H,179,229)(H,180,237)(H,181,218)(H,182,230)(H,183,234)(H,184,235)(H,185,238)(H,186,239)(H,187,225)(H,188,236)(H,189,240)(H,190,205)(H,191,232)(H,192,227)(H,193,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,158,159,162)/t76-,77-,78-,79-,80-,81+,82+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.0120n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273756
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C156H238N42O45/c1-18-81(10)126(153(241)191-109(64-89-34-21-19-22-35-89)143(231)176-85(14)133(221)186-112(67-92-70-168-97-39-26-25-38-95(92)97)146(234)188-108(63-78(4)5)147(235)195-124(79(6)7)151(239)184-99(40-27-30-58-157)135(223)169-72-117(206)177-98(129(162)217)43-33-61-167-156(163)164)197-142(230)106(52-57-122(213)214)182-139(227)100(41-28-31-59-158)179-131(219)83(12)173-130(218)82(11)175-138(226)104(48-53-115(160)204)178-118(207)73-170-137(225)103(51-56-121(211)212)181-144(232)107(62-77(2)3)187-145(233)110(66-91-44-46-94(203)47-45-91)189-141(229)105(49-54-116(161)205)183-150(238)114(75-199)193-152(240)125(80(8)9)196-149(237)113(69-123(215)216)190-140(228)101(42-29-32-60-166-88(17)202)185-155(243)128(87(16)201)198-148(236)111(65-90-36-23-20-24-37-90)192-154(242)127(86(15)200)194-119(208)74-171-136(224)102(50-55-120(209)210)180-132(220)84(13)174-134(222)96(159)68-93-71-165-76-172-93/h19-26,34-39,44-47,70-71,76-87,96,98-114,124-128,168,199-201,203H,18,27-33,40-43,48-69,72-75,157-159H2,1-17H3,(H2,160,204)(H2,161,205)(H2,162,217)(H,165,172)(H,166,202)(H,169,223)(H,170,225)(H,171,224)(H,173,218)(H,174,222)(H,175,226)(H,176,231)(H,177,206)(H,178,207)(H,179,219)(H,180,220)(H,181,232)(H,182,227)(H,183,238)(H,184,239)(H,185,243)(H,186,221)(H,187,233)(H,188,234)(H,189,229)(H,190,228)(H,191,241)(H,192,242)(H,193,240)(H,194,208)(H,195,235)(H,196,237)(H,197,230)(H,198,236)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,163,164,167)/t81-,82-,83-,84-,85-,86+,87+,96-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,124-,125-,126-,127-,128-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 15n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273752
PNG
(CHEMBL503836 | HAEGTFTSDVSSYLEGQAAKEIFAWLVKGR)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1S/C149H225N39O46/c1-17-76(10)119(145(230)179-101(57-83-31-20-18-21-32-83)133(218)166-80(14)125(210)174-104(60-86-63-158-91-36-25-24-35-89(86)91)136(221)176-100(56-73(4)5)137(222)185-117(74(6)7)143(228)173-92(37-26-28-52-150)127(212)159-66-111(197)168-98(148(233)234)39-30-54-157-149(154)155)187-132(217)97(47-51-115(203)204)172-131(216)93(38-27-29-53-151)169-123(208)78(12)163-122(207)77(11)165-130(215)96(44-48-109(153)195)167-110(196)65-160-129(214)95(46-50-114(201)202)171-134(219)99(55-72(2)3)175-135(220)102(59-85-40-42-88(194)43-41-85)177-140(225)106(68-189)181-142(227)108(70-191)182-144(229)118(75(8)9)186-139(224)105(62-116(205)206)178-141(226)107(69-190)183-147(232)121(82(16)193)188-138(223)103(58-84-33-22-19-23-34-84)180-146(231)120(81(15)192)184-112(198)67-161-128(213)94(45-49-113(199)200)170-124(209)79(13)164-126(211)90(152)61-87-64-156-71-162-87/h18-25,31-36,40-43,63-64,71-82,90,92-108,117-121,158,189-194H,17,26-30,37-39,44-62,65-70,150-152H2,1-16H3,(H2,153,195)(H,156,162)(H,159,212)(H,160,214)(H,161,213)(H,163,207)(H,164,211)(H,165,215)(H,166,218)(H,167,196)(H,168,197)(H,169,208)(H,170,209)(H,171,219)(H,172,216)(H,173,228)(H,174,210)(H,175,220)(H,176,221)(H,177,225)(H,178,226)(H,179,230)(H,180,231)(H,181,227)(H,182,229)(H,183,232)(H,184,198)(H,185,222)(H,186,224)(H,187,217)(H,188,223)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H,233,234)(H4,154,155,157)/t76-,77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,117-,118-,119-,120-,121-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00360n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273754
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C154H236N42O44/c1-17-81(10)125(152(239)189-108(63-88-33-20-18-21-34-88)141(228)174-85(14)131(218)184-111(66-91-68-166-96-38-25-24-37-94(91)96)144(231)186-107(62-78(4)5)145(232)194-123(79(6)7)150(237)183-98(39-26-29-57-155)133(220)167-70-117(205)175-97(127(160)214)42-32-60-165-154(161)162)195-140(227)105(51-56-122(212)213)181-138(225)100(40-27-30-58-156)178-129(216)83(12)171-128(215)82(11)173-136(223)103(47-52-115(158)203)177-119(207)72-169-135(222)102(50-55-121(210)211)180-142(229)106(61-77(2)3)185-143(230)109(65-90-43-45-93(202)46-44-90)188-148(235)112(73-197)190-149(236)114(75-199)191-151(238)124(80(8)9)193-139(226)104(48-53-116(159)204)182-147(234)113(74-198)192-153(240)126(86(15)200)196-146(233)110(64-89-35-22-19-23-36-89)187-137(224)99(41-28-31-59-164-87(16)201)176-118(206)71-168-134(221)101(49-54-120(208)209)179-130(217)84(13)172-132(219)95(157)67-92-69-163-76-170-92/h18-25,33-38,43-46,68-69,76-86,95,97-114,123-126,166,197-200,202H,17,26-32,39-42,47-67,70-75,155-157H2,1-16H3,(H2,158,203)(H2,159,204)(H2,160,214)(H,163,170)(H,164,201)(H,167,220)(H,168,221)(H,169,222)(H,171,215)(H,172,219)(H,173,223)(H,174,228)(H,175,205)(H,176,206)(H,177,207)(H,178,216)(H,179,217)(H,180,229)(H,181,225)(H,182,234)(H,183,237)(H,184,218)(H,185,230)(H,186,231)(H,187,224)(H,188,235)(H,189,239)(H,190,236)(H,191,238)(H,192,240)(H,193,226)(H,194,232)(H,195,227)(H,196,233)(H,208,209)(H,210,211)(H,212,213)(H4,161,162,165)/t81-,82-,83-,84-,85-,86+,95-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 23n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273769
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C144H214N40O45S2/c1-13-71(6)114(141(227)174-95(52-78-27-16-14-17-28-78)129(215)162-75(10)121(207)170-98(55-81-58-154-86-32-21-20-31-84(81)86)131(217)171-94(51-69(2)3)133(219)182-113(70(4)5)140(226)169-88(33-22-24-48-145)123(209)155-60-106(192)163-87(117(149)203)35-26-50-153-144(150)151)183-128(214)93(43-47-111(199)200)168-127(213)89(34-23-25-49-146)165-119(205)73(8)159-118(204)72(7)161-126(212)92(40-44-105(148)191)164-107(193)61-156-125(211)91(42-46-110(197)198)167-138(224)103-66-230-231-67-104(139(225)177-101(64-186)137(223)176-100(63-185)135(221)172-96(130(216)179-103)54-80-36-38-83(190)39-37-80)180-132(218)99(57-112(201)202)173-136(222)102(65-187)178-143(229)116(77(12)189)184-134(220)97(53-79-29-18-15-19-30-79)175-142(228)115(76(11)188)181-108(194)62-157-124(210)90(41-45-109(195)196)166-120(206)74(9)160-122(208)85(147)56-82-59-152-68-158-82/h14-21,27-32,36-39,58-59,68-77,85,87-104,113-116,154,185-190H,13,22-26,33-35,40-57,60-67,145-147H2,1-12H3,(H2,148,191)(H2,149,203)(H,152,158)(H,155,209)(H,156,211)(H,157,210)(H,159,204)(H,160,208)(H,161,212)(H,162,215)(H,163,192)(H,164,193)(H,165,205)(H,166,206)(H,167,224)(H,168,213)(H,169,226)(H,170,207)(H,171,217)(H,172,221)(H,173,222)(H,174,227)(H,175,228)(H,176,223)(H,177,225)(H,178,229)(H,179,216)(H,180,218)(H,181,194)(H,182,219)(H,183,214)(H,184,220)(H,195,196)(H,197,198)(H,199,200)(H,201,202)(H4,150,151,153)/t71-,72-,73-,74-,75-,76+,77+,85-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,113-,114-,115-,116-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 19n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273768
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C153H231N41O47/c1-17-78(10)123(150(239)185-105(59-85-31-20-18-21-32-85)139(228)176-96(38-27-29-55-162-84(16)200)136(225)183-107(62-88-65-164-93-36-25-24-35-91(88)93)141(230)181-103(58-75(4)5)142(231)191-121(76(6)7)148(237)179-97(44-49-112(156)202)131(220)165-67-114(204)172-94(126(158)215)39-30-56-163-153(159)160)193-137(226)101(48-53-119(211)212)178-135(224)95(37-26-28-54-154)174-128(217)80(12)169-127(216)79(11)171-134(223)100(45-50-113(157)203)173-115(205)68-166-133(222)99(47-52-118(209)210)177-138(227)102(57-74(2)3)180-140(229)104(61-87-40-42-90(201)43-41-87)182-145(234)109(70-195)187-147(236)111(72-197)188-149(238)122(77(8)9)192-144(233)108(64-120(213)214)184-146(235)110(71-196)189-152(241)125(83(15)199)194-143(232)106(60-86-33-22-19-23-34-86)186-151(240)124(82(14)198)190-116(206)69-167-132(221)98(46-51-117(207)208)175-129(218)81(13)170-130(219)92(155)63-89-66-161-73-168-89/h18-25,31-36,40-43,65-66,73-83,92,94-111,121-125,164,195-199,201H,17,26-30,37-39,44-64,67-72,154-155H2,1-16H3,(H2,156,202)(H2,157,203)(H2,158,215)(H,161,168)(H,162,200)(H,165,220)(H,166,222)(H,167,221)(H,169,216)(H,170,219)(H,171,223)(H,172,204)(H,173,205)(H,174,217)(H,175,218)(H,176,228)(H,177,227)(H,178,224)(H,179,237)(H,180,229)(H,181,230)(H,182,234)(H,183,225)(H,184,235)(H,185,239)(H,186,240)(H,187,236)(H,188,238)(H,189,241)(H,190,206)(H,191,231)(H,192,233)(H,193,226)(H,194,232)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H4,159,160,163)/t78-,79-,80-,81-,82+,83+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,121-,122-,123-,124-,125-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00479n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273761
PNG
((3S,6S,9S,12S,15S,21S)-3-((S)-1-((S)-1-((S)-1-((S)...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C151H227N41O46/c1-14-77(8)121(148(236)183-102(59-83-30-17-15-18-31-83)137(225)169-80(11)127(215)179-105(62-86-65-162-91-35-22-21-34-89(86)91)139(227)180-101(58-74(2)3)140(228)189-119(75(4)5)146(234)178-93(36-23-26-54-152)129(217)163-67-112(201)170-92(124(156)212)39-29-57-161-151(157)158)191-136(224)100(48-53-117(208)209)177-133(221)94(37-24-27-55-153)172-126(214)79(10)168-132(220)99-45-50-111(200)160-56-28-25-38-95(134(222)175-97(47-52-116(206)207)131(219)164-68-113(202)171-98(135(223)176-99)44-49-110(155)199)174-138(226)103(61-85-40-42-88(198)43-41-85)181-143(231)107(70-193)185-145(233)109(72-195)186-147(235)120(76(6)7)190-142(230)106(64-118(210)211)182-144(232)108(71-194)187-150(238)123(82(13)197)192-141(229)104(60-84-32-19-16-20-33-84)184-149(237)122(81(12)196)188-114(203)69-165-130(218)96(46-51-115(204)205)173-125(213)78(9)167-128(216)90(154)63-87-66-159-73-166-87/h15-22,30-35,40-43,65-66,73-82,90,92-109,119-123,162,193-198H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,199)(H2,156,212)(H,159,166)(H,160,200)(H,163,217)(H,164,219)(H,165,218)(H,167,216)(H,168,220)(H,169,225)(H,170,201)(H,171,202)(H,172,214)(H,173,213)(H,174,226)(H,175,222)(H,176,223)(H,177,221)(H,178,234)(H,179,215)(H,180,227)(H,181,231)(H,182,232)(H,183,236)(H,184,237)(H,185,233)(H,186,235)(H,187,238)(H,188,203)(H,189,228)(H,190,230)(H,191,224)(H,192,229)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H4,157,158,161)/t77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.363n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273765
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C150H228N40O43/c1-17-78(10)120(147(231)181-103(59-85-33-20-18-21-34-85)135(219)168-82(14)127(211)176-106(62-88-65-160-93-38-25-24-37-91(88)93)138(222)178-102(58-75(4)5)139(223)187-118(76(6)7)145(229)175-95(39-26-29-53-151)129(213)161-67-112(198)169-94(123(154)207)42-32-56-159-150(155)156)189-134(218)100-47-50-111(197)158-55-31-28-41-96(132(216)167-79(11)124(208)165-80(12)125(209)171-97(133(217)174-100)40-27-30-54-152)170-113(199)68-162-131(215)99(49-52-116(203)204)173-136(220)101(57-74(2)3)177-137(221)104(61-87-43-45-90(196)46-44-87)179-142(226)108(70-191)183-144(228)110(72-193)184-146(230)119(77(8)9)188-141(225)107(64-117(205)206)180-143(227)109(71-192)185-149(233)122(84(16)195)190-140(224)105(60-86-35-22-19-23-36-86)182-148(232)121(83(15)194)186-114(200)69-163-130(214)98(48-51-115(201)202)172-126(210)81(13)166-128(212)92(153)63-89-66-157-73-164-89/h18-25,33-38,43-46,65-66,73-84,92,94-110,118-122,160,191-196H,17,26-32,39-42,47-64,67-72,151-153H2,1-16H3,(H2,154,207)(H,157,164)(H,158,197)(H,161,213)(H,162,215)(H,163,214)(H,165,208)(H,166,212)(H,167,216)(H,168,219)(H,169,198)(H,170,199)(H,171,209)(H,172,210)(H,173,220)(H,174,217)(H,175,229)(H,176,211)(H,177,221)(H,178,222)(H,179,226)(H,180,227)(H,181,231)(H,182,232)(H,183,228)(H,184,230)(H,185,233)(H,186,200)(H,187,223)(H,188,225)(H,189,218)(H,190,224)(H,201,202)(H,203,204)(H,205,206)(H4,155,156,159)/t78-,79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,120-,121-,122-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00288n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273763
PNG
((3S,6S,9S,12S,15S,21S)-3-((3S,6S,9S,12S,15S)-15-((...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C152H231N41O44/c1-16-79(10)122(149(235)184-104(60-85-32-19-17-20-33-85)137(223)170-82(13)128(214)179-107(63-88-66-163-93-37-24-23-36-91(88)93)140(226)181-103(59-76(4)5)141(227)190-120(77(6)7)147(233)178-96(38-25-28-54-153)131(217)164-68-114(202)171-94(125(157)211)41-31-57-162-152(158)159)192-136(222)101(49-53-118(207)208)177-134(220)97(39-26-29-55-154)176-135(221)100-47-51-113(201)161-56-30-27-40-95(130(216)165-69-115(203)172-99(46-50-112(156)200)133(219)169-81(12)127(213)174-100)175-138(224)102(58-75(2)3)180-139(225)105(62-87-42-44-90(199)45-43-87)182-144(230)109(71-194)186-146(232)111(73-196)187-148(234)121(78(8)9)191-143(229)108(65-119(209)210)183-145(231)110(72-195)188-151(237)124(84(15)198)193-142(228)106(61-86-34-21-18-22-35-86)185-150(236)123(83(14)197)189-116(204)70-166-132(218)98(48-52-117(205)206)173-126(212)80(11)168-129(215)92(155)64-89-67-160-74-167-89/h17-24,32-37,42-45,66-67,74-84,92,94-111,120-124,163,194-199H,16,25-31,38-41,46-65,68-73,153-155H2,1-15H3,(H2,156,200)(H2,157,211)(H,160,167)(H,161,201)(H,164,217)(H,165,216)(H,166,218)(H,168,215)(H,169,219)(H,170,223)(H,171,202)(H,172,203)(H,173,212)(H,174,213)(H,175,224)(H,176,221)(H,177,220)(H,178,233)(H,179,214)(H,180,225)(H,181,226)(H,182,230)(H,183,231)(H,184,235)(H,185,236)(H,186,232)(H,187,234)(H,188,237)(H,189,204)(H,190,227)(H,191,229)(H,192,222)(H,193,228)(H,205,206)(H,207,208)(H,209,210)(H4,158,159,162)/t79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.10n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273755
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C154H233N41O44/c1-17-80(10)124(151(237)188-107(63-87-33-20-18-21-34-87)141(227)173-84(14)131(217)183-110(66-90-69-165-95-38-25-24-37-93(90)95)144(230)185-106(62-77(4)5)145(231)192-122(78(6)7)149(235)181-97(39-26-29-57-155)133(219)166-71-115(202)174-96(127(159)213)42-32-60-164-154(160)161)194-140(226)104(51-56-120(209)210)179-137(223)98(40-27-30-58-156)176-129(215)82(12)170-128(214)81(11)172-136(222)102(47-52-113(158)200)175-116(203)72-167-135(221)101(50-55-119(207)208)178-142(228)105(61-76(2)3)184-143(229)108(65-89-43-45-92(199)46-44-89)186-139(225)103-48-53-114(201)163-59-31-28-41-99(138(224)187-111(68-121(211)212)147(233)193-123(79(8)9)150(236)190-112(74-196)148(234)180-103)182-153(239)126(86(16)198)195-146(232)109(64-88-35-22-19-23-36-88)189-152(238)125(85(15)197)191-117(204)73-168-134(220)100(49-54-118(205)206)177-130(216)83(13)171-132(218)94(157)67-91-70-162-75-169-91/h18-25,33-38,43-46,69-70,75-86,94,96-112,122-126,165,196-199H,17,26-32,39-42,47-68,71-74,155-157H2,1-16H3,(H2,158,200)(H2,159,213)(H,162,169)(H,163,201)(H,166,219)(H,167,221)(H,168,220)(H,170,214)(H,171,218)(H,172,222)(H,173,227)(H,174,202)(H,175,203)(H,176,215)(H,177,216)(H,178,228)(H,179,223)(H,180,234)(H,181,235)(H,182,239)(H,183,217)(H,184,229)(H,185,230)(H,186,225)(H,187,224)(H,188,237)(H,189,238)(H,190,236)(H,191,204)(H,192,231)(H,193,233)(H,194,226)(H,195,232)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H4,160,161,164)/t80-,81-,82-,83-,84-,85+,86+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 8.30n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273771
PNG
((4S,7S,10S,13S,16S,22S)-4-((2S,3S)-1-((S)-1-((2S,5...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C151H223N41O47/c1-12-76(6)121(148(237)184-103(59-82-28-15-13-16-29-82)139(228)174-93-35-22-25-55-159-111(200)49-43-95(129(218)163-67-113(202)170-91(124(155)213)37-27-57-161-151(156)157)179-147(236)120(75(4)5)190-142(231)101(58-74(2)3)180-140(229)105(182-134(93)223)62-85-65-162-90-33-20-19-32-88(85)90)191-137(226)100(47-53-118(209)210)177-133(222)92(34-21-24-54-152)172-126(215)78(8)167-125(214)77(7)169-132(221)98(42-48-110(154)199)171-114(203)68-164-131(220)97(46-52-117(207)208)176-136(225)99-44-50-112(201)160-56-26-23-36-94(135(224)186-108(71-194)146(235)187-107(70-193)144(233)181-102(138(227)178-99)61-84-38-40-87(198)41-39-84)175-141(230)106(64-119(211)212)183-145(234)109(72-195)188-150(239)123(81(11)197)192-143(232)104(60-83-30-17-14-18-31-83)185-149(238)122(80(10)196)189-115(204)69-165-130(219)96(45-51-116(205)206)173-127(216)79(9)168-128(217)89(153)63-86-66-158-73-166-86/h13-20,28-33,38-41,65-66,73-81,89,91-109,120-123,162,193-198H,12,21-27,34-37,42-64,67-72,152-153H2,1-11H3,(H2,154,199)(H2,155,213)(H,158,166)(H,159,200)(H,160,201)(H,163,218)(H,164,220)(H,165,219)(H,167,214)(H,168,217)(H,169,221)(H,170,202)(H,171,203)(H,172,215)(H,173,216)(H,174,228)(H,175,230)(H,176,225)(H,177,222)(H,178,227)(H,179,236)(H,180,229)(H,181,233)(H,182,223)(H,183,234)(H,184,237)(H,185,238)(H,186,224)(H,187,235)(H,188,239)(H,189,204)(H,190,231)(H,191,226)(H,192,232)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H4,156,157,161)/t76-,77-,78-,79-,80+,81+,89-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00331n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273767
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C151H226N40O46/c1-16-77(10)121(148(235)182-103(58-83-30-19-17-20-31-83)137(224)173-94-37-26-28-54-159-111(199)49-44-95(129(216)162-66-112(200)169-92(124(155)211)38-29-55-160-151(156)157)176-146(233)119(75(6)7)188-140(227)101(57-74(4)5)178-139(226)105(180-134(94)221)61-86-64-161-91-35-24-23-34-89(86)91)190-135(222)99(47-52-117(207)208)175-133(220)93(36-25-27-53-152)171-126(213)79(12)166-125(212)78(11)168-132(219)98(43-48-110(154)198)170-113(201)67-163-131(218)97(46-51-116(205)206)174-136(223)100(56-73(2)3)177-138(225)102(60-85-39-41-88(197)42-40-85)179-143(230)107(69-192)184-145(232)109(71-194)185-147(234)120(76(8)9)189-142(229)106(63-118(209)210)181-144(231)108(70-193)186-150(237)123(82(15)196)191-141(228)104(59-84-32-21-18-22-33-84)183-149(236)122(81(14)195)187-114(202)68-164-130(217)96(45-50-115(203)204)172-127(214)80(13)167-128(215)90(153)62-87-65-158-72-165-87/h17-24,30-35,39-42,64-65,72-82,90,92-109,119-123,161,192-197H,16,25-29,36-38,43-63,66-71,152-153H2,1-15H3,(H2,154,198)(H2,155,211)(H,158,165)(H,159,199)(H,162,216)(H,163,218)(H,164,217)(H,166,212)(H,167,215)(H,168,219)(H,169,200)(H,170,201)(H,171,213)(H,172,214)(H,173,224)(H,174,223)(H,175,220)(H,176,233)(H,177,225)(H,178,226)(H,179,230)(H,180,221)(H,181,231)(H,182,235)(H,183,236)(H,184,232)(H,185,234)(H,186,237)(H,187,202)(H,188,227)(H,189,229)(H,190,222)(H,191,228)(H,203,204)(H,205,206)(H,207,208)(H,209,210)(H4,156,157,160)/t77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00209n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273753
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C152H231N41O43/c1-16-80(10)123(150(235)186-106(62-86-32-19-17-20-33-86)139(224)171-84(14)129(214)181-109(65-89-67-163-94-37-24-23-36-92(89)94)142(227)183-105(61-77(4)5)143(228)191-121(78(6)7)148(233)180-96(38-25-28-56-153)131(216)164-69-115(201)172-95(125(157)210)41-31-59-162-152(158)159)192-138(223)103(50-55-120(208)209)178-136(221)98(39-26-29-57-154)175-127(212)82(12)168-126(211)81(11)170-134(219)101(46-51-113(156)199)174-117(203)71-166-133(218)100(49-54-119(206)207)177-140(225)104(60-76(2)3)182-141(226)107(64-88-42-44-91(198)45-43-88)185-146(231)110(72-194)187-147(232)112(74-196)188-149(234)122(79(8)9)190-137(222)102-47-52-114(200)161-58-30-27-40-97(135(220)184-108(63-87-34-21-18-22-35-87)144(229)193-124(85(15)197)151(236)189-111(73-195)145(230)179-102)173-116(202)70-165-132(217)99(48-53-118(204)205)176-128(213)83(13)169-130(215)93(155)66-90-68-160-75-167-90/h17-24,32-37,42-45,67-68,75-85,93,95-112,121-124,163,194-198H,16,25-31,38-41,46-66,69-74,153-155H2,1-15H3,(H2,156,199)(H2,157,210)(H,160,167)(H,161,200)(H,164,216)(H,165,217)(H,166,218)(H,168,211)(H,169,215)(H,170,219)(H,171,224)(H,172,201)(H,173,202)(H,174,203)(H,175,212)(H,176,213)(H,177,225)(H,178,221)(H,179,230)(H,180,233)(H,181,214)(H,182,226)(H,183,227)(H,184,220)(H,185,231)(H,186,235)(H,187,232)(H,188,234)(H,189,236)(H,190,222)(H,191,228)(H,192,223)(H,193,229)(H,204,205)(H,206,207)(H,208,209)(H4,158,159,162)/t80-,81-,82-,83-,84-,85+,93-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.380n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273753
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C152H231N41O43/c1-16-80(10)123(150(235)186-106(62-86-32-19-17-20-33-86)139(224)171-84(14)129(214)181-109(65-89-67-163-94-37-24-23-36-92(89)94)142(227)183-105(61-77(4)5)143(228)191-121(78(6)7)148(233)180-96(38-25-28-56-153)131(216)164-69-115(201)172-95(125(157)210)41-31-59-162-152(158)159)192-138(223)103(50-55-120(208)209)178-136(221)98(39-26-29-57-154)175-127(212)82(12)168-126(211)81(11)170-134(219)101(46-51-113(156)199)174-117(203)71-166-133(218)100(49-54-119(206)207)177-140(225)104(60-76(2)3)182-141(226)107(64-88-42-44-91(198)45-43-88)185-146(231)110(72-194)187-147(232)112(74-196)188-149(234)122(79(8)9)190-137(222)102-47-52-114(200)161-58-30-27-40-97(135(220)184-108(63-87-34-21-18-22-35-87)144(229)193-124(85(15)197)151(236)189-111(73-195)145(230)179-102)173-116(202)70-165-132(217)99(48-53-118(204)205)176-128(213)83(13)169-130(215)93(155)66-90-68-160-75-167-90/h17-24,32-37,42-45,67-68,75-85,93,95-112,121-124,163,194-198H,16,25-31,38-41,46-66,69-74,153-155H2,1-15H3,(H2,156,199)(H2,157,210)(H,160,167)(H,161,200)(H,164,216)(H,165,217)(H,166,218)(H,168,211)(H,169,215)(H,170,219)(H,171,224)(H,172,201)(H,173,202)(H,174,203)(H,175,212)(H,176,213)(H,177,225)(H,178,221)(H,179,230)(H,180,233)(H,181,214)(H,182,226)(H,183,227)(H,184,220)(H,185,231)(H,186,235)(H,187,232)(H,188,234)(H,189,236)(H,190,222)(H,191,228)(H,192,223)(H,193,229)(H,204,205)(H,206,207)(H,208,209)(H4,158,159,162)/t80-,81-,82-,83-,84-,85+,93-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.380n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273762
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C153H232N42O47/c1-15-78(8)123(150(240)186-104(60-85-31-18-16-19-32-85)139(229)172-81(11)129(219)182-107(63-88-66-165-93-36-23-22-35-91(88)93)141(231)183-103(59-75(2)3)142(232)192-121(76(4)5)148(238)181-95(37-24-27-55-154)131(221)166-68-114(205)173-94(126(159)216)40-30-58-164-153(160)161)194-138(228)102(49-54-119(212)213)180-135(225)96(38-25-28-56-155)175-128(218)80(10)171-134(224)101(46-51-113(158)204)179-137(227)100(45-50-112(157)203)174-115(206)69-167-133(223)99(48-53-118(210)211)178-136(226)97(39-26-29-57-163-84(14)201)177-140(230)105(62-87-41-43-90(202)44-42-87)184-145(235)109(71-196)188-147(237)111(73-198)189-149(239)122(77(6)7)193-144(234)108(65-120(214)215)185-146(236)110(72-197)190-152(242)125(83(13)200)195-143(233)106(61-86-33-20-17-21-34-86)187-151(241)124(82(12)199)191-116(207)70-168-132(222)98(47-52-117(208)209)176-127(217)79(9)170-130(220)92(156)64-89-67-162-74-169-89/h16-23,31-36,41-44,66-67,74-83,92,94-111,121-125,165,196-200,202H,15,24-30,37-40,45-65,68-73,154-156H2,1-14H3,(H2,157,203)(H2,158,204)(H2,159,216)(H,162,169)(H,163,201)(H,166,221)(H,167,223)(H,168,222)(H,170,220)(H,171,224)(H,172,229)(H,173,205)(H,174,206)(H,175,218)(H,176,217)(H,177,230)(H,178,226)(H,179,227)(H,180,225)(H,181,238)(H,182,219)(H,183,231)(H,184,235)(H,185,236)(H,186,240)(H,187,241)(H,188,237)(H,189,239)(H,190,242)(H,191,207)(H,192,232)(H,193,234)(H,194,228)(H,195,233)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H4,160,161,164)/t78-,79-,80-,81-,82+,83+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,121-,122-,123-,124-,125-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.102n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273764
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C154H236N42O45/c1-17-80(10)124(151(239)187-106(61-87-33-20-18-21-34-87)139(227)173-83(13)130(218)182-109(64-90-67-166-95-38-25-24-37-93(90)95)142(230)184-105(60-77(4)5)143(231)193-122(78(6)7)149(237)181-98(39-26-29-55-155)133(221)167-69-116(206)174-96(127(160)215)42-32-58-165-154(161)162)195-138(226)103(50-54-120(211)212)180-136(224)99(40-27-30-56-156)179-137(225)102(48-52-115(159)205)177-129(217)82(12)172-135(223)101(47-51-114(158)204)175-117(207)70-168-132(220)97(41-28-31-57-164-86(16)202)178-140(228)104(59-76(2)3)183-141(229)107(63-89-43-45-92(203)46-44-89)185-146(234)111(72-197)189-148(236)113(74-199)190-150(238)123(79(8)9)194-145(233)110(66-121(213)214)186-147(235)112(73-198)191-153(241)126(85(15)201)196-144(232)108(62-88-35-22-19-23-36-88)188-152(240)125(84(14)200)192-118(208)71-169-134(222)100(49-53-119(209)210)176-128(216)81(11)171-131(219)94(157)65-91-68-163-75-170-91/h18-25,33-38,43-46,67-68,75-85,94,96-113,122-126,166,197-201,203H,17,26-32,39-42,47-66,69-74,155-157H2,1-16H3,(H2,158,204)(H2,159,205)(H2,160,215)(H,163,170)(H,164,202)(H,167,221)(H,168,220)(H,169,222)(H,171,219)(H,172,223)(H,173,227)(H,174,206)(H,175,207)(H,176,216)(H,177,217)(H,178,228)(H,179,225)(H,180,224)(H,181,237)(H,182,218)(H,183,229)(H,184,230)(H,185,234)(H,186,235)(H,187,239)(H,188,240)(H,189,236)(H,190,238)(H,191,241)(H,192,208)(H,193,231)(H,194,233)(H,195,226)(H,196,232)(H,209,210)(H,211,212)(H,213,214)(H4,161,162,165)/t80-,81-,82-,83-,84+,85+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.123n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273757
PNG
((4S,7S,10S,13S,16S,22S)-4-((6S,12S,15S,18S,21S,24S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C149H223N41O46/c1-13-75(6)119(146(234)182-101(58-82-29-16-14-17-30-82)136(224)168-79(10)126(214)178-104(61-85-64-160-90-34-21-20-33-88(85)90)138(226)179-100(57-73(2)3)140(228)188-118(74(4)5)145(233)177-92(35-22-25-53-150)128(216)161-66-111(199)169-91(122(154)210)38-28-56-159-149(155)156)189-135(223)99(47-52-116(206)207)175-132(220)93(36-23-26-54-151)171-124(212)77(8)165-123(211)76(7)167-131(219)97(43-48-109(153)197)170-112(200)67-162-130(218)96(46-51-115(204)205)174-134(222)98-44-49-110(198)158-55-27-24-37-94(133(221)184-107(70-192)144(232)185-106(69-191)142(230)180-102(137(225)176-98)60-84-39-41-87(196)42-40-84)173-139(227)105(63-117(208)209)181-143(231)108(71-193)186-148(236)121(81(12)195)190-141(229)103(59-83-31-18-15-19-32-83)183-147(235)120(80(11)194)187-113(201)68-163-129(217)95(45-50-114(202)203)172-125(213)78(9)166-127(215)89(152)62-86-65-157-72-164-86/h14-21,29-34,39-42,64-65,72-81,89,91-108,118-121,160,191-196H,13,22-28,35-38,43-63,66-71,150-152H2,1-12H3,(H2,153,197)(H2,154,210)(H,157,164)(H,158,198)(H,161,216)(H,162,218)(H,163,217)(H,165,211)(H,166,215)(H,167,219)(H,168,224)(H,169,199)(H,170,200)(H,171,212)(H,172,213)(H,173,227)(H,174,222)(H,175,220)(H,176,225)(H,177,233)(H,178,214)(H,179,226)(H,180,230)(H,181,231)(H,182,234)(H,183,235)(H,184,221)(H,185,232)(H,186,236)(H,187,201)(H,188,228)(H,189,223)(H,190,229)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H4,155,156,159)/t75-,76-,77-,78-,79-,80+,81+,89-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,118-,119-,120-,121-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00759n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273759
PNG
((3S,6S,9S,12S,15S,21S)-3-((S)-1-((S)-1-((2S,5S,8S,...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C155H235N41O45/c1-17-80(10)124(152(239)188-107(63-87-33-20-18-21-34-87)141(228)173-84(14)131(218)183-110(66-90-69-166-95-38-25-24-37-93(90)95)144(231)185-106(62-77(4)5)145(232)193-122(78(6)7)150(237)182-97(39-26-29-57-156)133(220)167-71-116(204)174-96(127(160)214)42-32-60-165-155(161)162)195-140(227)104(51-56-120(210)211)180-136(223)98(40-27-30-58-157)175-129(216)82(12)170-128(215)81(11)172-135(222)101(47-52-114(159)202)178-138(225)102-48-53-115(203)164-59-31-28-41-99(137(224)186-108(65-89-43-45-92(201)46-44-89)143(230)184-105(61-76(2)3)142(229)181-103(139(226)179-102)50-55-119(208)209)177-148(235)112(73-197)190-151(238)123(79(8)9)194-147(234)111(68-121(212)213)187-149(236)113(74-198)191-154(241)126(86(16)200)196-146(233)109(64-88-35-22-19-23-36-88)189-153(240)125(85(15)199)192-117(205)72-168-134(221)100(49-54-118(206)207)176-130(217)83(13)171-132(219)94(158)67-91-70-163-75-169-91/h18-25,33-38,43-46,69-70,75-86,94,96-113,122-126,166,197-201H,17,26-32,39-42,47-68,71-74,156-158H2,1-16H3,(H2,159,202)(H2,160,214)(H,163,169)(H,164,203)(H,167,220)(H,168,221)(H,170,215)(H,171,219)(H,172,222)(H,173,228)(H,174,204)(H,175,216)(H,176,217)(H,177,235)(H,178,225)(H,179,226)(H,180,223)(H,181,229)(H,182,237)(H,183,218)(H,184,230)(H,185,231)(H,186,224)(H,187,236)(H,188,239)(H,189,240)(H,190,238)(H,191,241)(H,192,205)(H,193,232)(H,194,234)(H,195,227)(H,196,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,161,162,165)/t80-,81-,82-,83-,84-,85+,86+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,123-,124-,125-,126-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00199n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273760
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37S,40S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C157H240N42O46/c1-18-81(10)126(154(243)191-109(64-89-34-21-19-22-35-89)143(232)176-85(14)133(222)186-112(67-92-70-169-97-39-26-25-38-95(92)97)146(235)188-108(63-78(4)5)147(236)196-124(79(6)7)152(241)185-99(40-27-30-58-158)135(224)170-72-118(208)177-98(129(163)218)43-33-61-168-157(164)165)198-142(231)106(52-57-122(214)215)183-138(227)100(41-28-31-59-159)178-131(220)83(12)173-130(219)82(11)175-137(226)103(48-53-116(161)206)181-140(229)104(49-54-117(162)207)182-141(230)105(51-56-121(212)213)184-144(233)107(62-77(2)3)187-145(234)110(66-91-44-46-94(205)47-45-91)189-139(228)101(42-29-32-60-167-88(17)204)180-150(239)114(74-200)193-153(242)125(80(8)9)197-149(238)113(69-123(216)217)190-151(240)115(75-201)194-156(245)128(87(16)203)199-148(237)111(65-90-36-23-20-24-37-90)192-155(244)127(86(15)202)195-119(209)73-171-136(225)102(50-55-120(210)211)179-132(221)84(13)174-134(223)96(160)68-93-71-166-76-172-93/h19-26,34-39,44-47,70-71,76-87,96,98-115,124-128,169,200-203,205H,18,27-33,40-43,48-69,72-75,158-160H2,1-17H3,(H2,161,206)(H2,162,207)(H2,163,218)(H,166,172)(H,167,204)(H,170,224)(H,171,225)(H,173,219)(H,174,223)(H,175,226)(H,176,232)(H,177,208)(H,178,220)(H,179,221)(H,180,239)(H,181,229)(H,182,230)(H,183,227)(H,184,233)(H,185,241)(H,186,222)(H,187,234)(H,188,235)(H,189,228)(H,190,240)(H,191,243)(H,192,244)(H,193,242)(H,194,245)(H,195,209)(H,196,236)(H,197,238)(H,198,231)(H,199,237)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,168)/t81-,82-,83-,84-,85-,86+,87+,96-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,124-,125-,126-,127-,128-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00380n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273770
PNG
((4S,7S,10S,13S,16S,22S,25R,28S,31S,34S,37R,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O
Show InChI InChI=1S/C144H216N40O45S2/c1-13-71(6)114(141(227)174-95(52-78-27-16-14-17-28-78)129(215)162-75(10)121(207)170-98(55-81-58-154-86-32-21-20-31-84(81)86)131(217)171-94(51-69(2)3)133(219)182-113(70(4)5)140(226)169-88(33-22-24-48-145)123(209)155-60-106(192)163-87(117(149)203)35-26-50-153-144(150)151)183-128(214)93(43-47-111(199)200)168-127(213)89(34-23-25-49-146)165-119(205)73(8)159-118(204)72(7)161-126(212)92(40-44-105(148)191)164-107(193)61-156-125(211)91(42-46-110(197)198)167-138(224)103(66-230)179-130(216)96(54-80-36-38-83(190)39-37-80)172-135(221)100(63-185)176-137(223)101(64-186)177-139(225)104(67-231)180-132(218)99(57-112(201)202)173-136(222)102(65-187)178-143(229)116(77(12)189)184-134(220)97(53-79-29-18-15-19-30-79)175-142(228)115(76(11)188)181-108(194)62-157-124(210)90(41-45-109(195)196)166-120(206)74(9)160-122(208)85(147)56-82-59-152-68-158-82/h14-21,27-32,36-39,58-59,68-77,85,87-104,113-116,154,185-190,230-231H,13,22-26,33-35,40-57,60-67,145-147H2,1-12H3,(H2,148,191)(H2,149,203)(H,152,158)(H,155,209)(H,156,211)(H,157,210)(H,159,204)(H,160,208)(H,161,212)(H,162,215)(H,163,192)(H,164,193)(H,165,205)(H,166,206)(H,167,224)(H,168,213)(H,169,226)(H,170,207)(H,171,217)(H,172,221)(H,173,222)(H,174,227)(H,175,228)(H,176,223)(H,177,225)(H,178,229)(H,179,216)(H,180,218)(H,181,194)(H,182,219)(H,183,214)(H,184,220)(H,195,196)(H,197,198)(H,199,200)(H,201,202)(H4,150,151,153)/t71-,72-,73-,74-,75-,76+,77+,85-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,113-,114-,115-,116-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.40n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))
BDBM50273766
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1S/C152H233N41O44/c1-18-79(10)122(149(235)184-105(60-87-34-21-19-22-35-87)137(223)171-83(14)129(215)179-108(63-90-66-163-95-39-26-25-38-93(90)95)140(226)181-104(59-76(4)5)141(227)190-120(77(6)7)147(233)178-97(40-27-30-54-153)131(217)164-68-114(202)172-96(125(157)211)43-33-57-162-152(158)159)192-136(222)102(48-51-113(156)201)177-135(221)99(41-28-31-55-154)174-127(213)81(12)168-126(212)80(11)170-134(220)98(42-29-32-56-161-86(17)199)173-115(203)69-165-133(219)101(50-53-118(207)208)176-138(224)103(58-75(2)3)180-139(225)106(62-89-44-46-92(200)47-45-89)182-144(230)110(71-194)186-146(232)112(73-196)187-148(234)121(78(8)9)191-143(229)109(65-119(209)210)183-145(231)111(72-195)188-151(237)124(85(16)198)193-142(228)107(61-88-36-23-20-24-37-88)185-150(236)123(84(15)197)189-116(204)70-166-132(218)100(49-52-117(205)206)175-128(214)82(13)169-130(216)94(155)64-91-67-160-74-167-91/h19-26,34-39,44-47,66-67,74-85,94,96-112,120-124,163,194-198,200H,18,27-33,40-43,48-65,68-73,153-155H2,1-17H3,(H2,156,201)(H2,157,211)(H,160,167)(H,161,199)(H,164,217)(H,165,219)(H,166,218)(H,168,212)(H,169,216)(H,170,220)(H,171,223)(H,172,202)(H,173,203)(H,174,213)(H,175,214)(H,176,224)(H,177,221)(H,178,233)(H,179,215)(H,180,225)(H,181,226)(H,182,230)(H,183,231)(H,184,235)(H,185,236)(H,186,232)(H,187,234)(H,188,237)(H,189,204)(H,190,227)(H,191,229)(H,192,222)(H,193,228)(H,205,206)(H,207,208)(H,209,210)(H4,158,159,162)/t79-,80-,81-,82-,83-,84+,85+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,120-,121-,122-,123-,124-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.00282n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression


Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%