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PubMed code 1895293

Compile data set for download or QSAR
Found 44 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(RAT)
BDBM50229528
PNG
(CHEMBL93406)
Show SMILES Cc1noc(n1)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C9H13N3O/c1-6-10-9(13-11-6)8-5-12-3-2-7(8)4-12/h7-8H,2-5H2,1H3/t7-,8-/m1/s1
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n/an/a 2.80n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM10759
PNG
(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)
Show SMILES CC(=O)OCC[N+](C)(C)C
Show InChI InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1
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n/an/a 12n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229526
PNG
(CHEMBL279356)
Show SMILES Cc1noc(n1)C1CN2CCC1CC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(14-12-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3
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n/an/a 14n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229524
PNG
(CHEMBL329351)
Show SMILES Cc1noc(n1)C12CCN(C1)CCC2
Show InChI InChI=1S/C10H15N3O/c1-8-11-9(14-12-8)10-3-2-5-13(7-10)6-4-10/h2-7H2,1H3
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n/an/a 15n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central Muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229530
PNG
(CHEMBL329434)
Show SMILES COC(=O)C12CCN(C1)CCC2
Show InChI InChI=1S/C9H15NO2/c1-12-8(11)9-3-2-5-10(7-9)6-4-9/h2-7H2,1H3
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n/an/a 19n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229520
PNG
(CHEMBL93430)
Show SMILES Cc1noc(n1)[C@@H]1C[C@H]2CC[N@@](C2)C1
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(14-12-7)9-4-8-2-3-13(5-8)6-9/h8-9H,2-6H2,1H3/t8-,9-/m1/s1
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n/an/a 28n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229527
PNG
(CHEMBL94072)
Show SMILES Cc1nnc(o1)C12CCN(C1)CCC2
Show InChI InChI=1S/C10H15N3O/c1-8-11-12-9(14-8)10-3-2-5-13(7-10)6-4-10/h2-7H2,1H3
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n/an/a 42n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229535
PNG
(CHEMBL91390)
Show SMILES Cc1noc(n1)[C@@H]1C[N@@]2C[C@H]1CCC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(14-12-7)9-6-13-4-2-3-8(9)5-13/h8-9H,2-6H2,1H3/t8-,9-/m1/s1
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n/an/a 44n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229533
PNG
(CHEMBL330709)
Show SMILES COC(=O)C12CCN(CC1)C2
Show InChI InChI=1S/C8H13NO2/c1-11-7(10)8-2-4-9(6-8)5-3-8/h2-6H2,1H3
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n/an/a 48n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229536
PNG
(CHEMBL329321)
Show SMILES COC(=O)[C@@H]1C[C@H]2CC[N@@](C2)C1
Show InChI InChI=1S/C9H15NO2/c1-12-9(11)8-4-7-2-3-10(5-7)6-8/h7-8H,2-6H2,1H3/t7-,8-/m1/s1
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n/an/a 77n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229539
PNG
(CHEMBL93126)
Show SMILES Cc1nc(no1)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C9H13N3O/c1-6-10-9(11-13-6)8-5-12-3-2-7(8)4-12/h7-8H,2-5H2,1H3/t7-,8-/m1/s1
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n/an/a 92n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229531
PNG
(CHEMBL328152)
Show SMILES Cc1nnc(o1)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C9H13N3O/c1-6-10-11-9(13-6)8-5-12-3-2-7(8)4-12/h7-8H,2-5H2,1H3/t7-,8-/m1/s1
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n/an/a 120n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229522
PNG
(CHEMBL329316)
Show SMILES COC(=O)[C@@H]1C[C@H]2CCC[N@@](C2)C1
Show InChI InChI=1S/C10H17NO2/c1-13-10(12)9-5-8-3-2-4-11(6-8)7-9/h8-9H,2-7H2,1H3/t8-,9-/m1/s1
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n/an/a 130n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229538
PNG
(CHEMBL91907)
Show SMILES Cc1noc(n1)C12CCN(CC1)C2
Show InChI InChI=1S/C9H13N3O/c1-7-10-8(13-11-7)9-2-4-12(6-9)5-3-9/h2-6H2,1H3
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n/an/a 130n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229525
PNG
(CHEMBL94065)
Show SMILES Cc1nnc(o1)C12CCN(CC1)C2
Show InChI InChI=1S/C9H13N3O/c1-7-10-11-8(13-7)9-2-4-12(6-9)5-3-9/h2-6H2,1H3
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n/an/a 180n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229532
PNG
(CHEMBL445119)
Show SMILES COC(=O)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C8H13NO2/c1-11-8(10)7-5-9-3-2-6(7)4-9/h6-7H,2-5H2,1H3/t6-,7-/m1/s1
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n/an/a 230n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229521
PNG
(CHEMBL91850)
Show SMILES Cc1noc(n1)[C@@H]1C[C@H]2CCC[N@@](C2)C1
Show InChI InChI=1S/C11H17N3O/c1-8-12-11(15-13-8)10-5-9-3-2-4-14(6-9)7-10/h9-10H,2-7H2,1H3/t9-,10-/m1/s1
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n/an/a 260n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested for muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Value ranges from 250...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229537
PNG
(CHEMBL328497)
Show SMILES Cc1nc(no1)C12CCN(C1)CCC2
Show InChI InChI=1S/C10H15N3O/c1-8-11-9(12-14-8)10-3-2-5-13(7-10)6-4-10/h2-7H2,1H3
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n/an/a 260n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50212556
PNG
(CHEMBL14648)
Show SMILES COC(=O)C1CN2CCC1CC2
Show InChI InChI=1S/C9H15NO2/c1-12-9(11)8-6-10-4-2-7(8)3-5-10/h7-8H,2-6H2,1H3
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n/an/a 520n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229529
PNG
(CHEMBL14879)
Show SMILES Cc1nnc(o1)C1CN2CCC1CC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-12-10(14-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3
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n/an/a 980n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229528
PNG
(CHEMBL93406)
Show SMILES Cc1noc(n1)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C9H13N3O/c1-6-10-9(13-11-6)8-5-12-3-2-7(8)4-12/h7-8H,2-5H2,1H3/t7-,8-/m1/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229534
PNG
(CHEMBL14808)
Show SMILES Cc1nc(no1)C1CN2CCC1CC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(12-14-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229523
PNG
(CHEMBL328267)
Show SMILES COC(=O)[C@@H]1C[N@@]2C[C@H]1CCC2
Show InChI InChI=1S/C9H15NO2/c1-12-9(11)8-6-10-4-2-3-7(8)5-10/h7-8H,2-6H2,1H3/t7-,8-/m1/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Valu...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229521
PNG
(CHEMBL91850)
Show SMILES Cc1noc(n1)[C@@H]1C[C@H]2CCC[N@@](C2)C1
Show InChI InChI=1S/C11H17N3O/c1-8-12-11(15-13-8)10-5-9-3-2-4-14(6-9)7-10/h9-10H,2-7H2,1H3/t9-,10-/m1/s1
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n/an/a 1.73E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229526
PNG
(CHEMBL279356)
Show SMILES Cc1noc(n1)C1CN2CCC1CC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(14-12-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3
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n/an/a 1.80E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229535
PNG
(CHEMBL91390)
Show SMILES Cc1noc(n1)[C@@H]1C[N@@]2C[C@H]1CCC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(14-12-7)9-6-13-4-2-3-8(9)5-13/h8-9H,2-6H2,1H3/t8-,9-/m1/s1
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n/an/a 2.40E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229520
PNG
(CHEMBL93430)
Show SMILES Cc1noc(n1)[C@@H]1C[C@H]2CC[N@@](C2)C1
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(14-12-7)9-4-8-2-3-13(5-8)6-9/h8-9H,2-6H2,1H3/t8-,9-/m1/s1
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n/an/a 2.40E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229524
PNG
(CHEMBL329351)
Show SMILES Cc1noc(n1)C12CCN(C1)CCC2
Show InChI InChI=1S/C10H15N3O/c1-8-11-9(14-12-8)10-3-2-5-13(7-10)6-4-10/h2-7H2,1H3
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n/an/a 3.50E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central Muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229537
PNG
(CHEMBL328497)
Show SMILES Cc1nc(no1)C12CCN(C1)CCC2
Show InChI InChI=1S/C10H15N3O/c1-8-11-9(12-14-8)10-3-2-5-13(7-10)6-4-10/h2-7H2,1H3
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n/an/a 4.20E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229522
PNG
(CHEMBL329316)
Show SMILES COC(=O)[C@@H]1C[C@H]2CCC[N@@](C2)C1
Show InChI InChI=1S/C10H17NO2/c1-13-10(12)9-5-8-3-2-4-11(6-8)7-9/h8-9H,2-7H2,1H3/t8-,9-/m1/s1
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n/an/a 4.80E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229530
PNG
(CHEMBL329434)
Show SMILES COC(=O)C12CCN(C1)CCC2
Show InChI InChI=1S/C9H15NO2/c1-12-8(11)9-3-2-5-10(7-9)6-4-9/h2-7H2,1H3
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n/an/a 6.40E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229527
PNG
(CHEMBL94072)
Show SMILES Cc1nnc(o1)C12CCN(C1)CCC2
Show InChI InChI=1S/C10H15N3O/c1-8-11-12-9(14-8)10-3-2-5-13(7-10)6-4-10/h2-7H2,1H3
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n/an/a 9.40E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229534
PNG
(CHEMBL14808)
Show SMILES Cc1nc(no1)C1CN2CCC1CC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-10(12-14-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3
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n/an/a 1.20E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229536
PNG
(CHEMBL329321)
Show SMILES COC(=O)[C@@H]1C[C@H]2CC[N@@](C2)C1
Show InChI InChI=1S/C9H15NO2/c1-12-9(11)8-4-7-2-3-10(5-7)6-8/h7-8H,2-6H2,1H3/t7-,8-/m1/s1
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n/an/a 1.20E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229529
PNG
(CHEMBL14879)
Show SMILES Cc1nnc(o1)C1CN2CCC1CC2
Show InChI InChI=1S/C10H15N3O/c1-7-11-12-10(14-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3
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n/an/a 1.90E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229538
PNG
(CHEMBL91907)
Show SMILES Cc1noc(n1)C12CCN(CC1)C2
Show InChI InChI=1S/C9H13N3O/c1-7-10-8(13-11-7)9-2-4-12(6-9)5-3-9/h2-6H2,1H3
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n/an/a 2.30E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM10759
PNG
(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)
Show SMILES CC(=O)OCC[N+](C)(C)C
Show InChI InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1
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n/an/a 2.40E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50212556
PNG
(CHEMBL14648)
Show SMILES COC(=O)C1CN2CCC1CC2
Show InChI InChI=1S/C9H15NO2/c1-12-9(11)8-6-10-4-2-7(8)3-5-10/h7-8H,2-6H2,1H3
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n/an/a 2.50E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229539
PNG
(CHEMBL93126)
Show SMILES Cc1nc(no1)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C9H13N3O/c1-6-10-9(11-13-6)8-5-12-3-2-7(8)4-12/h7-8H,2-5H2,1H3/t7-,8-/m1/s1
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n/an/a 2.70E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229531
PNG
(CHEMBL328152)
Show SMILES Cc1nnc(o1)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C9H13N3O/c1-6-10-11-9(13-6)8-5-12-3-2-7(8)4-12/h7-8H,2-5H2,1H3/t7-,8-/m1/s1
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n/an/a 2.90E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229533
PNG
(CHEMBL330709)
Show SMILES COC(=O)C12CCN(CC1)C2
Show InChI InChI=1S/C8H13NO2/c1-11-7(10)8-2-4-9(6-8)5-3-8/h2-6H2,1H3
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n/an/a 3.10E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229532
PNG
(CHEMBL445119)
Show SMILES COC(=O)[C@@H]1C[N@]2CC[C@@H]1C2
Show InChI InChI=1S/C8H13NO2/c1-11-8(10)7-5-9-3-2-6(7)4-9/h6-7H,2-5H2,1H3/t6-,7-/m1/s1
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n/an/a 5.10E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229523
PNG
(CHEMBL328267)
Show SMILES COC(=O)[C@@H]1C[N@@]2C[C@H]1CCC2
Show InChI InChI=1S/C9H15NO2/c1-12-9(11)8-6-10-4-2-3-7(8)5-10/h7-8H,2-6H2,1H3/t7-,8-/m1/s1
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n/an/a 6.20E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50229525
PNG
(CHEMBL94065)
Show SMILES Cc1nnc(o1)C12CCN(CC1)C2
Show InChI InChI=1S/C9H13N3O/c1-7-10-11-8(13-7)9-2-4-12(6-9)5-3-9/h2-6H2,1H3
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n/an/a 7.00E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cor...


J Med Chem 34: 2726-35 (1991)


Article DOI: 10.1021/jm00113a009
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%