Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM93008![]() (Substituted Quinazolin-4(3H)-one, 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 1.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arizona State University | Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm. | Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM93004![]() (Substituted Quinazolin-4(3H)-one, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 1.42E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arizona State University | Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm. | Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM93003![]() (Substituted Quinazolin-4(3H)-one, 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem | Article PubMed | 3.37E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arizona State University | Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm. | Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM93006![]() (Substituted Quinazolin-4(3H)-one, 13) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Similars | Article PubMed | 5.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arizona State University | Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm. | Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM93007![]() (Substituted Quinazolin-4(3H)-one, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 5.93E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arizona State University | Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm. | Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM93005![]() (Substituted Quinazolin-4(3H)-one, 12) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 6.18E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arizona State University | Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm. | Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS | |||||||||||
More data for this Ligand-Target Pair |