Affinity Data by PubMed id=1909177

PubMed code 1909177

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM93008 (Substituted Quinazolin-4(3H)-one, 15) Show SMILES Nc1ccc(O)c2c1nc[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University					Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm.				Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS
Arizona State University					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM93004 (Substituted Quinazolin-4(3H)-one, 11) Show SMILES Oc1ccc(O)c2c1nc[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University					Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm.				Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS
Arizona State University					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM93003 (Substituted Quinazolin-4(3H)-one, 9) Show SMILES Nc1cccc2nc[nH]c(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	Article PubMed	3.37E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University					Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm.				Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS
Arizona State University					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM93006 (Substituted Quinazolin-4(3H)-one, 13) Show SMILES Oc1cccc2nc[nH]c(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.76E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University					Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm.				Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS
Arizona State University					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM93007 (Substituted Quinazolin-4(3H)-one, 14) Show SMILES Oc1cccc2c1nc[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	5.93E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University					Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm.				Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS
Arizona State University					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM93005 (Substituted Quinazolin-4(3H)-one, 12) Show SMILES Cc1cc(O)c2nc[nH]c(=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	6.18E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University					Assay Description PNPase activity (guanosine to guanine and ribose 1-phosphate) was followed by measuring the decrease in absorbance at 268nm.				Biochemistry 30: 8480-7 (1991) Article DOI: 10.1021/bi00098a028 BindingDB Entry DOI: 10.7270/Q2C53JGS
Arizona State University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%