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PubMed code 19095444

Compile data set for download or QSAR
Found 48 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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5.60n/an/an/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 1.90n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256075
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)N3CCCCC3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C21H18Cl4N4O/c22-13-4-6-15(17(24)10-13)20-21(16-7-5-14(23)11-18(16)25)27-29(26-20)12-19(30)28-8-2-1-3-9-28/h4-7,10-11H,1-3,8-9,12H2
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n/an/a 5.90n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256119
PNG
(CHEMBL474424 | N-benzyl-2-(4,5-bis(2,4-dichlorophe...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NCc3ccccc3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C23H16Cl4N4O/c24-15-6-8-17(19(26)10-15)22-23(18-9-7-16(25)11-20(18)27)30-31(29-22)13-21(32)28-12-14-4-2-1-3-5-14/h1-11H,12-13H2,(H,28,32)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256172
PNG
(2-(4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-2H-1,...)
Show SMILES Fc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H16Cl3FN4O/c24-16-5-3-15(4-6-16)22-23(19-10-7-17(25)11-20(19)26)30-31(29-22)13-21(32)28-12-14-1-8-18(27)9-2-14/h1-11H,12-13H2,(H,28,32)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256272
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NCc3ccccc3Cl)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C23H15Cl5N4O/c24-14-5-7-16(19(27)9-14)22-23(17-8-6-15(25)10-20(17)28)31-32(30-22)12-21(33)29-11-13-3-1-2-4-18(13)26/h1-10H,11-12H2,(H,29,33)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256273
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C23H15Cl5N4O/c24-14-3-1-13(2-4-14)11-29-21(33)12-32-30-22(17-7-5-15(25)9-19(17)27)23(31-32)18-8-6-16(26)10-20(18)28/h1-10H,11-12H2,(H,29,33)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256170
PNG
(2-(4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-2H-1,...)
Show SMILES Fc1ccccc1CNC(=O)Cn1nc(c(n1)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H16Cl3FN4O/c24-16-7-5-14(6-8-16)22-23(18-10-9-17(25)11-19(18)26)30-31(29-22)13-21(32)28-12-15-3-1-2-4-20(15)27/h1-11H,12-13H2,(H,28,32)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256271
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES COc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C24H18Cl4N4O2/c1-34-17-6-2-14(3-7-17)12-29-22(33)13-32-30-23(18-8-4-15(25)10-20(18)27)24(31-32)19-9-5-16(26)11-21(19)28/h2-11H,12-13H2,1H3,(H,29,33)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256171
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-3-7-17(19(26)9-14)22-23(18-8-4-15(25)10-20(18)27)31-32(30-22)12-21(33)29-11-13-1-5-16(28)6-2-13/h1-10H,11-12H2,(H,29,33)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256173
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1cccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-4-6-17(19(26)9-14)22-23(18-7-5-15(25)10-20(18)27)31-32(30-22)12-21(33)29-11-13-2-1-3-16(28)8-13/h1-10H,11-12H2,(H,29,33)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256122
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccccc1CNC(=O)Cn1nc(c(n1)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-5-7-16(18(26)9-14)22-23(17-8-6-15(25)10-19(17)27)31-32(30-22)12-21(33)29-11-13-3-1-2-4-20(13)28/h1-10H,11-12H2,(H,29,33)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256332
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)Nc3ccccc3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C22H14Cl4N4O/c23-13-6-8-16(18(25)10-13)21-22(17-9-7-14(24)11-19(17)26)29-30(28-21)12-20(31)27-15-4-2-1-3-5-15/h1-11H,12H2,(H,27,31)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256121
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NC3CCCCC3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C22H20Cl4N4O/c23-13-6-8-16(18(25)10-13)21-22(17-9-7-14(24)11-19(17)26)29-30(28-21)12-20(31)27-15-4-2-1-3-5-15/h6-11,15H,1-5,12H2,(H,27,31)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256274
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccc(F)c(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C23H14Cl4F2N4O/c24-13-1-4-16(18(26)8-13)22-23(17-5-2-14(25)9-19(17)27)32-33(31-22)11-21(34)30-10-12-7-15(28)3-6-20(12)29/h1-9H,10-11H2,(H,30,34)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50256120
PNG
(CHEMBL515118 | N-benzyl-2-(4-(4-chlorophenyl)-5-(2...)
Show SMILES Clc1ccc(cc1)-c1nn(CC(=O)NCc2ccccc2)nc1-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H17Cl3N4O/c24-17-8-6-16(7-9-17)22-23(19-11-10-18(25)12-20(19)26)29-30(28-22)14-21(31)27-13-15-4-2-1-3-5-15/h1-12H,13-14H2,(H,27,31)
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n/an/a>10n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256171
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-3-7-17(19(26)9-14)22-23(18-8-4-15(25)10-20(18)27)31-32(30-22)12-21(33)29-11-13-1-5-16(28)6-2-13/h1-10H,11-12H2,(H,29,33)
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n/an/a 11.6n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 15n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256122
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccccc1CNC(=O)Cn1nc(c(n1)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-5-7-16(18(26)9-14)22-23(17-8-6-15(25)10-19(17)27)31-32(30-22)12-21(33)29-11-13-3-1-2-4-20(13)28/h1-10H,11-12H2,(H,29,33)
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n/an/a 19.3n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256274
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccc(F)c(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C23H14Cl4F2N4O/c24-13-1-4-16(18(26)8-13)22-23(17-5-2-14(25)9-19(17)27)32-33(31-22)11-21(34)30-10-12-7-15(28)3-6-20(12)29/h1-9H,10-11H2,(H,30,34)
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n/an/a 22.6n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256173
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1cccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-4-6-17(19(26)9-14)22-23(18-7-5-15(25)10-20(18)27)31-32(30-22)12-21(33)29-11-13-2-1-3-16(28)8-13/h1-10H,11-12H2,(H,29,33)
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n/an/a 25.7n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256272
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NCc3ccccc3Cl)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C23H15Cl5N4O/c24-14-5-7-16(19(27)9-14)22-23(17-8-6-15(25)10-20(17)28)31-32(30-22)12-21(33)29-11-13-3-1-2-4-18(13)26/h1-10H,11-12H2,(H,29,33)
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n/an/a 48.9n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256273
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C23H15Cl5N4O/c24-14-3-1-13(2-4-14)11-29-21(33)12-32-30-22(17-7-5-15(25)9-19(17)27)23(31-32)18-8-6-16(26)10-20(18)28/h1-10H,11-12H2,(H,29,33)
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n/an/a 64.8n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256119
PNG
(CHEMBL474424 | N-benzyl-2-(4,5-bis(2,4-dichlorophe...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NCc3ccccc3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C23H16Cl4N4O/c24-15-6-8-17(19(26)10-15)22-23(18-9-7-16(25)11-20(18)27)30-31(29-22)13-21(32)28-12-14-4-2-1-3-5-14/h1-11H,12-13H2,(H,28,32)
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n/an/a 66.9n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256271
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES COc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C24H18Cl4N4O2/c1-34-17-6-2-14(3-7-17)12-29-22(33)13-32-30-23(18-8-4-15(25)10-20(18)27)24(31-32)19-9-5-16(26)11-21(19)28/h2-11H,12-13H2,1H3,(H,29,33)
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n/an/a 81.9n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256121
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NC3CCCCC3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C22H20Cl4N4O/c23-13-6-8-16(18(25)10-13)21-22(17-9-7-14(24)11-19(17)26)29-30(28-21)12-20(31)27-15-4-2-1-3-5-15/h6-11,15H,1-5,12H2,(H,27,31)
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n/an/a 144n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256075
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)N3CCCCC3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C21H18Cl4N4O/c22-13-4-6-15(17(24)10-13)20-21(16-7-5-14(23)11-18(16)25)27-29(26-20)12-19(30)28-8-2-1-3-9-28/h4-7,10-11H,1-3,8-9,12H2
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n/an/a 169n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256120
PNG
(CHEMBL515118 | N-benzyl-2-(4-(4-chlorophenyl)-5-(2...)
Show SMILES Clc1ccc(cc1)-c1nn(CC(=O)NCc2ccccc2)nc1-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H17Cl3N4O/c24-17-8-6-16(7-9-17)22-23(19-11-10-18(25)12-20(19)26)29-30(28-22)14-21(31)27-13-15-4-2-1-3-5-15/h1-12H,13-14H2,(H,27,31)
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n/an/a 204n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256332
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)Nc3ccccc3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C22H14Cl4N4O/c23-13-6-8-16(18(25)10-13)21-22(17-9-7-14(24)11-19(17)26)29-30(28-21)12-20(31)27-15-4-2-1-3-5-15/h1-11H,12H2,(H,27,31)
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n/an/a 251n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256170
PNG
(2-(4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-2H-1,...)
Show SMILES Fc1ccccc1CNC(=O)Cn1nc(c(n1)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H16Cl3FN4O/c24-16-7-5-14(6-8-16)22-23(18-10-9-17(25)11-19(18)26)30-31(29-22)13-21(32)28-12-15-3-1-2-4-20(15)27/h1-11H,12-13H2,(H,28,32)
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n/an/a 262n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256172
PNG
(2-(4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-2H-1,...)
Show SMILES Fc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H16Cl3FN4O/c24-16-5-3-15(4-6-16)22-23(19-10-7-17(25)11-20(19)26)30-31(29-22)13-21(32)28-12-14-1-8-18(27)9-2-14/h1-11H,12-13H2,(H,28,32)
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n/an/a 449n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256074
PNG
(CHEMBL481885 | butyl 2-(4,5-bis(2,4-dichlorophenyl...)
Show SMILES CCCCOC(=O)Cn1nc(c(n1)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H17Cl4N3O2/c1-2-3-8-29-18(28)11-27-25-19(14-6-4-12(21)9-16(14)23)20(26-27)15-7-5-13(22)10-17(15)24/h4-7,9-10H,2-3,8,11H2,1H3
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n/an/a 1.17E+3n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256747
PNG
(4,5-Bis-(2,4-dichloro-phenyl)-[1,2,3]triazole-2-ca...)
Show SMILES Clc1ccc(-c2nn(nc2-c2ccc(Cl)cc2Cl)C(=O)NC23CC4CC(CC(C4)C2)C3)c(Cl)c1
Show InChI InChI=1S/C25H22Cl4N4O/c26-16-1-3-18(20(28)8-16)22-23(19-4-2-17(27)9-21(19)29)32-33(31-22)24(34)30-25-10-13-5-14(11-25)7-15(6-13)12-25/h1-4,8-9,13-15H,5-7,10-12H2,(H,30,34)
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n/an/a 4.50E+3n/an/an/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256272
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NCc3ccccc3Cl)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C23H15Cl5N4O/c24-14-5-7-16(19(27)9-14)22-23(17-8-6-15(25)10-20(17)28)31-32(30-22)12-21(33)29-11-13-3-1-2-4-18(13)26/h1-10H,11-12H2,(H,29,33)
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n/an/an/an/a 12.2n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256172
PNG
(2-(4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-2H-1,...)
Show SMILES Fc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H16Cl3FN4O/c24-16-5-3-15(4-6-16)22-23(19-10-7-17(25)11-20(19)26)30-31(29-22)13-21(32)28-12-14-1-8-18(27)9-2-14/h1-11H,12-13H2,(H,28,32)
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n/an/an/an/a 235n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256120
PNG
(CHEMBL515118 | N-benzyl-2-(4-(4-chlorophenyl)-5-(2...)
Show SMILES Clc1ccc(cc1)-c1nn(CC(=O)NCc2ccccc2)nc1-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H17Cl3N4O/c24-17-8-6-16(7-9-17)22-23(19-11-10-18(25)12-20(19)26)29-30(28-22)14-21(31)27-13-15-4-2-1-3-5-15/h1-12H,13-14H2,(H,27,31)
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n/an/an/an/a 216n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256274
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccc(F)c(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C23H14Cl4F2N4O/c24-13-1-4-16(18(26)8-13)22-23(17-5-2-14(25)9-19(17)27)32-33(31-22)11-21(34)30-10-12-7-15(28)3-6-20(12)29/h1-9H,10-11H2,(H,30,34)
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n/an/an/an/a 22n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256119
PNG
(CHEMBL474424 | N-benzyl-2-(4,5-bis(2,4-dichlorophe...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NCc3ccccc3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C23H16Cl4N4O/c24-15-6-8-17(19(26)10-15)22-23(18-9-7-16(25)11-20(18)27)30-31(29-22)13-21(32)28-12-14-4-2-1-3-5-14/h1-11H,12-13H2,(H,28,32)
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n/an/an/an/a 87n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256170
PNG
(2-(4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-2H-1,...)
Show SMILES Fc1ccccc1CNC(=O)Cn1nc(c(n1)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H16Cl3FN4O/c24-16-7-5-14(6-8-16)22-23(18-10-9-17(25)11-19(18)26)30-31(29-22)13-21(32)28-12-15-3-1-2-4-20(15)27/h1-11H,12-13H2,(H,28,32)
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n/an/an/an/a 256n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256122
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccccc1CNC(=O)Cn1nc(c(n1)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-5-7-16(18(26)9-14)22-23(17-8-6-15(25)10-19(17)27)31-32(30-22)12-21(33)29-11-13-3-1-2-4-20(13)28/h1-10H,11-12H2,(H,29,33)
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n/an/an/an/a 23.5n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256173
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1cccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)c1
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-4-6-17(19(26)9-14)22-23(18-7-5-15(25)10-20(18)27)31-32(30-22)12-21(33)29-11-13-2-1-3-16(28)8-13/h1-10H,11-12H2,(H,29,33)
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n/an/an/an/a 35.1n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/an/an/a 18.2n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256332
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)Nc3ccccc3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C22H14Cl4N4O/c23-13-6-8-16(18(25)10-13)21-22(17-9-7-14(24)11-19(17)26)29-30(28-21)12-20(31)27-15-4-2-1-3-5-15/h1-11H,12H2,(H,27,31)
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n/an/an/an/a 136n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256271
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES COc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C24H18Cl4N4O2/c1-34-17-6-2-14(3-7-17)12-29-22(33)13-32-30-23(18-8-4-15(25)10-20(18)27)24(31-32)19-9-5-16(26)11-21(19)28/h2-11H,12-13H2,1H3,(H,29,33)
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n/an/an/an/a 56.2n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256121
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)NC3CCCCC3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C22H20Cl4N4O/c23-13-6-8-16(18(25)10-13)21-22(17-9-7-14(24)11-19(17)26)29-30(28-21)12-20(31)27-15-4-2-1-3-5-15/h6-11,15H,1-5,12H2,(H,27,31)
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n/an/an/an/a 204n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256075
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(-c2nn(CC(=O)N3CCCCC3)nc2-c2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C21H18Cl4N4O/c22-13-4-6-15(17(24)10-13)20-21(16-7-5-14(23)11-18(16)25)27-29(26-20)12-19(30)28-8-2-1-3-9-28/h4-7,10-11H,1-3,8-9,12H2
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n/an/an/an/a 122n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256171
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Fc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C23H15Cl4FN4O/c24-14-3-7-17(19(26)9-14)22-23(18-8-4-15(25)10-20(18)27)31-32(30-22)12-21(33)29-11-13-1-5-16(28)6-2-13/h1-10H,11-12H2,(H,29,33)
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n/an/an/an/a 50.7n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50256273
PNG
(2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-...)
Show SMILES Clc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C23H15Cl5N4O/c24-14-3-1-13(2-4-14)11-29-21(33)12-32-30-22(17-7-5-15(25)9-19(17)27)23(31-32)18-8-6-16(26)10-20(18)28/h1-10H,11-12H2,(H,29,33)
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n/an/an/an/a 17.8n/an/an/an/a



National Central University

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding


Bioorg Med Chem Lett 19: 1022-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.029
BindingDB Entry DOI: 10.7270/Q2Z89C8M
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%