Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50027955
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  31nMAssay Description:Inhibition of PDGFRb (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256724(CHEMBL475794 | N-(5-chloropyridin-3-yl)-5-(3-(2-cy...)
Affinity DataIC50:  400nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  478nMAssay Description:Inhibition of PTK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  672nMAssay Description:Inhibition of EphB4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  700nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256751(CHEMBL514670 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256679(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(5-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256727(CHEMBL475799 | N-(6-amino-5-chloropyridin-3-yl)-5-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256636(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(6-...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256634(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(6-...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Jak2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Pak1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Plk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cdk2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Jnk1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kdr (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(CHEMBL475817 | N-(6-amino-5-chloropyridin-3-yl)-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Csk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed