Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50006774![]() ((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50006774![]() ((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50451132![]() (CHEMBL2079586 | WIN-35428) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50010195![]() ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM22418![]() (Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50010195![]() ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM22418![]() (Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 221 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50451132![]() (CHEMBL2079586 | WIN-35428) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 479 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals Inc. Curated by ChEMBL | Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r... | J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB | |||||||||||
More data for this Ligand-Target Pair |