Affinity Data by PubMed id=1920365

PubMed code 1920365

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dopamine Transporter (DAT) (Rattus norvegicus (rat))	BDBM50006774 ((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50006774 ((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine Transporter (DAT) (Rattus norvegicus (rat))	BDBM50451132 (CHEMBL2079586 \| WIN-35428) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine Transporter (DAT) (Rattus norvegicus (rat))	BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine transporters; serotonin & dopamine (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50451132 (CHEMBL2079586 \| WIN-35428) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	479	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r...				J Med Chem 34: 3144-6 (1991) Article DOI: 10.1021/jm00114a027 BindingDB Entry DOI: 10.7270/Q23R0TGB
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%