Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 3098
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27960((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/mole IC50:  3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27959(4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]ami...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/mole IC50:  330nM EC50:  9.10nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27955((-)-Zilpaterol | (9R,10R)-9-hydroxy-10-(propan-2-y...)
Affinity DataKi:  320nM ΔG°:  -36.7kJ/mole IC50:  620nM EC50:  8.70nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM25769(4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxym...)
Affinity DataKi:  510nM ΔG°:  -35.6kJ/mole IC50:  980nM EC50:  19nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27958(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Affinity DataKi:  570nM ΔG°:  -35.3kJ/mole IC50:  1.30E+3nM EC50:  6.20nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27956((rac)-Zilpaterol | 9-hydroxy-10-(propan-2-ylamino)...)
Affinity DataKi:  580nM ΔG°:  -35.2kJ/mole IC50:  1.10E+3nM EC50:  13nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27957((+)-Zilpaterol | (9S,10S)-9-hydroxy-10-(propan-2-y...)
Affinity DataKi:  7.00E+3nM ΔG°:  -29.1kJ/mole IC50:  1.70E+4nM EC50:  1.40E+5nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27955((-)-Zilpaterol | (9R,10R)-9-hydroxy-10-(propan-2-y...)
Affinity DataKi:  1.30E+5nM ΔG°:  -22.0kJ/mole IC50:  3.20E+5nM EC50: >1.00E+6nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27957((+)-Zilpaterol | (9S,10S)-9-hydroxy-10-(propan-2-y...)
Affinity DataEC50:  6.90E+3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed