Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 3196
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  85nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM21961((2S,4R)-4-[(2S)-2-amino-5-(1-nitrocarbamimidamido)...)
Affinity DataKi:  100nM ΔG°:  -40.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)
Affinity DataKi:  150nM ΔG°:  -39.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29235(aminopyridine-pyrrolidine, 7)
Affinity DataKi:  250nM ΔG°:  -38.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM22030((2S)-2-amino-N-[(1S)-3-amino-1-(aminocarbonyl)prop...)
Affinity DataKi:  300nM ΔG°:  -37.9kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29233(CHEMBL508014 | aminopyridine-pyrrolidine, 5)
Affinity DataKi:  388nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N,M336V](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  1.20E+3nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N,M336V](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29235(aminopyridine-pyrrolidine, 7)
Affinity DataKi:  6.10E+3nM ΔG°:  -30.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29232(3-({(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrroli...)
Affinity DataKi:  9.40E+3nM ΔG°:  -29.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N,M336V](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29233(CHEMBL508014 | aminopyridine-pyrrolidine, 5)
Affinity DataKi:  3.67E+4nM ΔG°:  -25.7kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N,M336V](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM29232(3-({(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrroli...)
Affinity DataKi:  4.92E+4nM ΔG°:  -25.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)
Affinity DataKi:  8.00E+4nM ΔG°:  -23.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  8.52E+4nM ΔG°:  -23.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM29235(aminopyridine-pyrrolidine, 7)
Affinity DataKi:  9.52E+4nM ΔG°:  -23.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM22030((2S)-2-amino-N-[(1S)-3-amino-1-(aminocarbonyl)prop...)
Affinity DataKi:  1.07E+5nM ΔG°:  -23.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM21961((2S,4R)-4-[(2S)-2-amino-5-(1-nitrocarbamimidamido)...)
Affinity DataKi:  1.10E+5nM ΔG°:  -23.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM29232(3-({(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrroli...)
Affinity DataKi:  3.67E+5nM ΔG°:  -19.9kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM29233(CHEMBL508014 | aminopyridine-pyrrolidine, 5)
Affinity DataKi:  4.17E+5nM ΔG°:  -19.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed