Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50030546
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297829(7-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-...)
Affinity DataKi:  5nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297828(7-(piperidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-4...)
Affinity DataKi:  9nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297839(7-(pyrrolidine-1-carbonyl)pyrrolo[1,2-a]quinoxalin...)
Affinity DataKi:  23nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297834(7-((3-morpholinopropylamino)methyl)pyrrolo[1,2-a]q...)
Affinity DataKi:  23nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297830(7-((isopropylamino)methyl)pyrrolo[1,2-a]quinoxalin...)
Affinity DataKi:  26nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297835(8-((cyclopropylamino)methyl)pyrrolo[1,2-a]quinoxal...)
Affinity DataKi:  31nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297827(7-((cyclopropylamino)methyl)pyrrolo[1,2-a]quinoxal...)
Affinity DataKi:  37nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297836(8-(piperidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-4...)
Affinity DataKi:  47nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297837(8-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-...)
Affinity DataKi:  48nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297848(3-((dimethylamino)methyl)-7,8,9,10-tetrahydro-5H-p...)
Affinity DataKi:  63nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297845(7-(pyrrolidin-1-ylmethyl)-1,2,3,3a-tetrahydropyrro...)
Affinity DataKi:  96nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297847(3-(pyrrolidin-1-ylmethyl)-7,8,9,10-tetrahydro-5H-p...)
Affinity DataKi:  115nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297833(7-((2-(pyrrolidin-1-yl)ethylamino)methyl)pyrrolo[1...)
Affinity DataKi:  133nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297838(4-oxo-N-(pyridin-4-ylmethyl)-4,5-dihydropyrrolo[1,...)
Affinity DataKi:  149nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297831(7-((benzylamino)methyl)pyrrolo[1,2-a]quinoxalin-4(...)
Affinity DataKi:  161nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297846(7-((dimethylamino)methyl)-1,2,3,3a-tetrahydropyrro...)
Affinity DataKi:  190nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297826(CHEMBL555751 | pyrrolo[1,2-a]quinoxalin-4(5H)-one)
Affinity DataKi:  238nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297840(4-oxo-N-(2-(pyrrolidin-1-yl)ethyl)-4,5-dihydropyrr...)
Affinity DataKi:  239nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297841(7-(pyrrolidin-1-ylmethyl)imidazo[1,2-a]quinoxalin-...)
Affinity DataKi:  280nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297842(7-((dimethylamino)methyl)imidazo[1,2-a]quinoxalin-...)
Affinity DataKi:  519nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297843(8-((dimethylamino)methyl)-5,6-dihydro-4H-benzo[f]p...)
Affinity DataKi:  589nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297832(7-((2-oxopyrrolidin-1-yl)methyl)pyrrolo[1,2-a]quin...)
Affinity DataKi:  698nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297844(8-(pyrrolidin-1-ylmethyl)-5,6-dihydro-4H-benzo[f]p...)
Affinity DataKi:  1.12E+3nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297847(3-(pyrrolidin-1-ylmethyl)-7,8,9,10-tetrahydro-5H-p...)
Affinity DataEC50:  58nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297848(3-((dimethylamino)methyl)-7,8,9,10-tetrahydro-5H-p...)
Affinity DataEC50:  39nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297828(7-(piperidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-4...)
Affinity DataEC50:  11nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297829(7-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-...)
Affinity DataEC50:  6nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297830(7-((isopropylamino)methyl)pyrrolo[1,2-a]quinoxalin...)
Affinity DataEC50:  14nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297831(7-((benzylamino)methyl)pyrrolo[1,2-a]quinoxalin-4(...)
Affinity DataEC50:  164nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297833(7-((2-(pyrrolidin-1-yl)ethylamino)methyl)pyrrolo[1...)
Affinity DataEC50:  171nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297834(7-((3-morpholinopropylamino)methyl)pyrrolo[1,2-a]q...)
Affinity DataEC50:  40nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297835(8-((cyclopropylamino)methyl)pyrrolo[1,2-a]quinoxal...)
Affinity DataEC50:  25nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297836(8-(piperidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-4...)
Affinity DataEC50:  31nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297837(8-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-...)
Affinity DataEC50:  29nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297839(7-(pyrrolidine-1-carbonyl)pyrrolo[1,2-a]quinoxalin...)
Affinity DataEC50:  280nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297845(7-(pyrrolidin-1-ylmethyl)-1,2,3,3a-tetrahydropyrro...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297846(7-((dimethylamino)methyl)-1,2,3,3a-tetrahydropyrro...)
Affinity DataEC50:  646nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50297827(7-((cyclopropylamino)methyl)pyrrolo[1,2-a]quinoxal...)
Affinity DataEC50:  39nMAssay Description:Inhibition of PARP1 in human C41 cells by DAPI staining-based FITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed