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PubMed code 1956033

Compile data set for download or QSAR
Found 121 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.0297n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.0383n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for binding activity against muscarinic acetylcholine receptor M1, using [3H]QNB as the radioligand.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.0540n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.0881n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.0986n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for binding activity against muscarinic acetylcholine receptor M3, using [3H]-QNB as the radioligand.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.118n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.130n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.166n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.177n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Compound was tested for binding activity against rat muscarinic acetylcholine receptor M2 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.196n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.197n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.220n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.224n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.254n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.279n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.297n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50403547
PNG
(ATROPEN | ATROPINE)
Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c1ccccc1
Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
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0.300n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of [3H]NMS binding against muscarinic acetylcholine receptor in rat brain


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.302n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50403547
PNG
(ATROPEN | ATROPINE)
Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c1ccccc1
Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
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0.337n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.449n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50403547
PNG
(ATROPEN | ATROPINE)
Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c1ccccc1
Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
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0.459n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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0.472n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.475n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Glutathione S-transferase theta 1


(Rattus norvegicus)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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0.680n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for binding activity against muscarinic acetylcholine receptor M3, using [3H]-QNB as the radioligand.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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1.10n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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1.20n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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1.90n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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2.90n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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2.90n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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4.10n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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4.20n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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4.30n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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4.80n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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5.5n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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5.70n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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6.40n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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7.90n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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8.20n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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9.30n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368151
PNG
(CHEMBL322582)
Show SMILES CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO2/c1-29(24-13-7-3-8-14-24,25-15-9-4-10-16-25)28(31)32-27-18-23-17-26(19-27)30(21-23)20-22-11-5-2-6-12-22/h2-16,23,26-27H,17-21H2,1H3
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9.30n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368151
PNG
(CHEMBL322582)
Show SMILES CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO2/c1-29(24-13-7-3-8-14-24,25-15-9-4-10-16-25)28(31)32-27-18-23-17-26(19-27)30(21-23)20-22-11-5-2-6-12-22/h2-16,23,26-27H,17-21H2,1H3
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9.5n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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9.60n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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11n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50368151
PNG
(CHEMBL322582)
Show SMILES CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO2/c1-29(24-13-7-3-8-14-24,25-15-9-4-10-16-25)28(31)32-27-18-23-17-26(19-27)30(21-23)20-22-11-5-2-6-12-22/h2-16,23,26-27H,17-21H2,1H3
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11n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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11n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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13n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368151
PNG
(CHEMBL322582)
Show SMILES CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO2/c1-29(24-13-7-3-8-14-24,25-15-9-4-10-16-25)28(31)32-27-18-23-17-26(19-27)30(21-23)20-22-11-5-2-6-12-22/h2-16,23,26-27H,17-21H2,1H3
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13n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50004656
PNG
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Show SMILES C[N+](C)(C)CCOC(N)=O
Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1
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13n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368151
PNG
(CHEMBL322582)
Show SMILES CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO2/c1-29(24-13-7-3-8-14-24,25-15-9-4-10-16-25)28(31)32-27-18-23-17-26(19-27)30(21-23)20-22-11-5-2-6-12-22/h2-16,23,26-27H,17-21H2,1H3
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13n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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13n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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15n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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17n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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19n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368151
PNG
(CHEMBL322582)
Show SMILES CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO2/c1-29(24-13-7-3-8-14-24,25-15-9-4-10-16-25)28(31)32-27-18-23-17-26(19-27)30(21-23)20-22-11-5-2-6-12-22/h2-16,23,26-27H,17-21H2,1H3
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28n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50008072
PNG
((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O
Show InChI InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
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83n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50453022
PNG
(CHEMBL326453)
Show SMILES CC(N1CC2CC1C[C@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14?,16?,17-/m0/s1
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113n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50008072
PNG
((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O
Show InChI InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
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1.01E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50008072
PNG
((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O
Show InChI InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
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1.11E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of [3H]NMS binding against muscarinic acetylcholine receptor in rat brain


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.15E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368149
PNG
(CHEMBL1159664)
Show SMILES CC(N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14-,16+,17+/m0/s1
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1.95E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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2.17E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50453022
PNG
(CHEMBL326453)
Show SMILES CC(N1CC2CC1C[C@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14?,16?,17-/m0/s1
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2.77E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50453022
PNG
(CHEMBL326453)
Show SMILES CC(N1CC2CC1C[C@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14?,16?,17-/m0/s1
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3.38E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50453022
PNG
(CHEMBL326453)
Show SMILES CC(N1CC2CC1C[C@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14?,16?,17-/m0/s1
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3.53E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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3.73E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for binding activity against muscarinic acetylcholine receptor M1, using [3H]QNB as the radioligand.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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3.75E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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4.15E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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4.19E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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4.28E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50453022
PNG
(CHEMBL326453)
Show SMILES CC(N1CC2CC1C[C@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14?,16?,17-/m0/s1
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4.57E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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4.71E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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4.97E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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6.47E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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6.55E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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7.11E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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7.21E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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7.53E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368149
PNG
(CHEMBL1159664)
Show SMILES CC(N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14-,16+,17+/m0/s1
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7.70E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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7.82E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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8.40E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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8.55E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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8.56E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for binding activity against muscarinic acetylcholine receptor M3, using [3H]-QNB as the radioligand.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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8.62E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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8.99E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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9.18E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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9.20E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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9.81E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368149
PNG
(CHEMBL1159664)
Show SMILES CC(N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14-,16+,17+/m0/s1
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1.01E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.04E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.04E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.13E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.19E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.25E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50368149
PNG
(CHEMBL1159664)
Show SMILES CC(N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14-,16+,17+/m0/s1
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1.28E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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1.29E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.39E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.41E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368149
PNG
(CHEMBL1159664)
Show SMILES CC(N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12?,14-,16+,17+/m0/s1
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1.49E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50004656
PNG
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Show SMILES C[N+](C)(C)CCOC(N)=O
Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1
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1.88E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50004656
PNG
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Show SMILES C[N+](C)(C)CCOC(N)=O
Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1
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1.88E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of [3H]NMS binding against muscarinic acetylcholine receptor in rat brain


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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1.91E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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1.97E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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2.10E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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2.21E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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2.30E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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2.31E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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2.33E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50453023
PNG
(CHEMBL2113669)
Show SMILES C[C@@H](N1C[C@H]2C[C@@H]1C[C@@H](C2)OC(C)=O)c1ccccc1
Show InChI InChI=1S/C17H23NO2/c1-12(15-6-4-3-5-7-15)18-11-14-8-16(18)10-17(9-14)20-13(2)19/h3-7,12,14,16-17H,8-11H2,1-2H3/t12-,14+,16-,17-/m1/s1
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2.99E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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3.39E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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3.81E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50368148
PNG
(CHEMBL325322)
Show SMILES CN1CC2CC1CC(C2)OC(C)=O
Show InChI InChI=1S/C10H17NO2/c1-7(12)13-10-4-8-3-9(5-10)11(2)6-8/h8-10H,3-6H2,1-2H3
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4.67E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligand


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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n/an/an/a 3.60n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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n/an/an/a 4.80n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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n/an/an/a 0.0120n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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n/an/an/a 5.40n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50011851
PNG
(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-23(18-9-5-3-6-10-18,19-11-7-4-8-12-19)22(25)26-21-14-17-13-20(15-21)24(2)16-17/h3-12,17,20-21H,13-16H2,1-2H3
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n/an/an/a 0.0347n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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n/an/an/a 0.447n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368150
PNG
(CHEMBL326640)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-23-15-16-12-19(23)14-20(13-16)25-22(24)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-21H,12-15H2,1H3
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n/an/an/a 3.5n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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n/an/an/a 0.302n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368151
PNG
(CHEMBL322582)
Show SMILES CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO2/c1-29(24-13-7-3-8-14-24,25-15-9-4-10-16-25)28(31)32-27-18-23-17-26(19-27)30(21-23)20-22-11-5-2-6-12-22/h2-16,23,26-27H,17-21H2,1H3
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n/an/an/a 9.10n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50368152
PNG
(CHEMBL318812)
Show SMILES CN1CC2CC1CC(C2)OC(=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO3/c1-23-15-16-12-19(23)14-20(13-16)26-21(24)22(25,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,19-20,25H,12-15H2,1H3
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PubMed
n/an/an/a 0.00776n/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of methacholine induced phasic contraction of guinea pig ileum


J Med Chem 34: 3164-71 (1991)


Article DOI: 10.1021/jm00115a003
BindingDB Entry DOI: 10.7270/Q2V988Q7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%