Affinity Data by PubMed id=1956041

PubMed code 1956041

Found 28 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM16314 (2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aldose reductase (Rattus norvegicus)	BDBM50010282 (2,7-difluorospiro[9H-fluorene-9,3'-(tetrahydro-1'H...) Show SMILES Fc1ccc2-c3ccc(F)cc3C3(CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Aldose reductase from rat lens				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010283 (2,7-difluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H...) Show SMILES Fc1ccc2-c3ccc(F)cc3C3(NC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010283 (2,7-difluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H...) Show SMILES Fc1ccc2-c3ccc(F)cc3C3(NC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010282 (2,7-difluorospiro[9H-fluorene-9,3'-(tetrahydro-1'H...) Show SMILES Fc1ccc2-c3ccc(F)cc3C3(CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010281 (2,7-Difluorospiro[9H-fluorene-9,5'-isothiazolidin]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50009777 ((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010281 (2,7-Difluorospiro[9H-fluorene-9,5'-isothiazolidin]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM16312 ((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...) Show SMILES Fc1ccc2OCC[C@]3(NC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aldose reductase (Rattus norvegicus)	BDBM50010286 (2-Chlorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010276 (2-Fluorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...) Show SMILES Fc1ccc2-c3ccccc3C3(CC(=O)NS3(=O)=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010276 (2-Fluorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...) Show SMILES Fc1ccc2-c3ccccc3C3(CC(=O)NS3(=O)=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010286 (2-Chlorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM16314 (2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aldose reductase (Rattus norvegicus)	BDBM16312 ((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...) Show SMILES Fc1ccc2OCC[C@]3(NC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aldose reductase (Rattus norvegicus)	BDBM7460 (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase from rat kidney				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010278 (CHEMBL325136 \| Spiro[9H-fluorene-9,5'-isothiazolid...) Show SMILES O=C1CC2(c3ccccc3-c3ccccc23)S(=O)(=O)N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010278 (CHEMBL325136 \| Spiro[9H-fluorene-9,5'-isothiazolid...) Show SMILES O=C1CC2(c3ccccc3-c3ccccc23)S(=O)(=O)N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010280 (2-Fluorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...) Show SMILES Fc1ccc2-c3ccccc3C3(CS(=O)(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50009777 ((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010285 (2-Chlorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010284 (2,7-DiFluorospiro[9H-fluorene-9,4'-isothiazolidin]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010277 (CHEMBL110661 \| Spiro[9H-fluorene-9,4'-isothiazolid...) Show SMILES O=C1NS(=O)(=O)CC11c2ccccc2-c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM7460 (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010285 (2-Chlorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.37E+6	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010284 (2,7-DiFluorospiro[9H-fluorene-9,4'-isothiazolidin]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.15E+6	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010280 (2-Fluorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...) Show SMILES Fc1ccc2-c3ccccc3C3(CS(=O)(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Aldose reductase (Rattus norvegicus)	BDBM50010277 (CHEMBL110661 \| Spiro[9H-fluorene-9,4'-isothiazolid...) Show SMILES O=C1NS(=O)(=O)CC11c2ccccc2-c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Aldose reductase (AR) from rat lens (RL)				J Med Chem 34: 3229-34 (1991) Article DOI: 10.1021/jm00115a011 BindingDB Entry DOI: 10.7270/Q2QJ7HXM
Alcon Laboratories, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%