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PubMed code 1967314

Compile data set for download or QSAR
Found 35 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
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n/an/a 2.60n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine as radioligand for Dopamine receptor D2 in rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
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n/an/a 27n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM81924
PNG
((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Show SMILES CCCN1CCCC(C1)c1cccc(O)c1
Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3
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n/an/a 184n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM81924
PNG
((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Show SMILES CCCN1CCCC(C1)c1cccc(O)c1
Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3
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n/an/a 184n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010580
PNG
(4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Show SMILES Nc1nc(cs1)C1=CCCN(CC=C)C1
Show InChI InChI=1S/C11H15N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h2,4,8H,1,3,5-7H2,(H2,12,13)
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n/an/a 257n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
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n/an/a 384n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determined


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010573
PNG
(4-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Show SMILES CCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C10H15N3S/c1-2-13-5-3-4-8(6-13)9-7-14-10(11)12-9/h4,7H,2-3,5-6H2,1H3,(H2,11,12)
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n/an/a 411n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010580
PNG
(4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Show SMILES Nc1nc(cs1)C1=CCCN(CC=C)C1
Show InChI InChI=1S/C11H15N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h2,4,8H,1,3,5-7H2,(H2,12,13)
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n/an/a 440n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM81924
PNG
((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Show SMILES CCCN1CCCC(C1)c1cccc(O)c1
Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3
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n/an/a 590n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50007573
PNG
(4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...)
Show SMILES CCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h4,8H,2-3,5-7H2,1H3,(H2,12,13)
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n/an/a 596n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367946
PNG
(CHEMBL1203001)
Show SMILES Nc1nc(cs1)C1=CCCN(CCc2ccccc2)C1
Show InChI InChI=1S/C16H19N3S/c17-16-18-15(12-20-16)14-7-4-9-19(11-14)10-8-13-5-2-1-3-6-13/h1-3,5-7,12H,4,8-11H2,(H2,17,18)
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n/an/a 911n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM81924
PNG
((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Show SMILES CCCN1CCCC(C1)c1cccc(O)c1
Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3
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n/an/a 930n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010573
PNG
(4-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Show SMILES CCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C10H15N3S/c1-2-13-5-3-4-8(6-13)9-7-14-10(11)12-9/h4,7H,2-3,5-6H2,1H3,(H2,11,12)
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n/an/a 945n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50007573
PNG
(4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...)
Show SMILES CCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h4,8H,2-3,5-7H2,1H3,(H2,12,13)
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n/an/a 958n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010571
PNG
(CHEMBL108682 | Methyl-[4-(1-propyl-1,2,5,6-tetrahy...)
Show SMILES CCCN1CCC=C(C1)c1csc(NC)n1
Show InChI InChI=1S/C12H19N3S/c1-3-6-15-7-4-5-10(8-15)11-9-16-12(13-2)14-11/h5,9H,3-4,6-8H2,1-2H3,(H,13,14)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367941
PNG
(CHEMBL1203003)
Show SMILES CCCCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C14H23N3S/c1-2-3-4-5-8-17-9-6-7-12(10-17)13-11-18-14(15)16-13/h7,11H,2-6,8-10H2,1H3,(H2,15,16)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (36%inhibition at 10 e-6 M)


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367942
PNG
(CHEMBL1203006)
Show SMILES CCCN1CCC=C(C1)c1csc(C)n1
Show InChI InChI=1S/C12H18N2S/c1-3-6-14-7-4-5-11(8-14)12-9-15-10(2)13-12/h5,9H,3-4,6-8H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (41% inhibition at 10 e-6 M)


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010575
PNG
(5-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-3H-1l...)
Show SMILES CCCN1CCC=C(C1)c1cnc(N)s1
Show InChI InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(8-14)10-7-13-11(12)15-10/h4,7H,2-3,5-6,8H2,1H3,(H2,12,13)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (2% inhibition at 10 e-6 M)


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010571
PNG
(CHEMBL108682 | Methyl-[4-(1-propyl-1,2,5,6-tetrahy...)
Show SMILES CCCN1CCC=C(C1)c1csc(NC)n1
Show InChI InChI=1S/C12H19N3S/c1-3-6-15-7-4-5-10(8-15)11-9-16-12(13-2)14-11/h5,9H,3-4,6-8H2,1-2H3,(H,13,14)
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Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (25% inhibition at 10 e-6 M)


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367947
PNG
(CHEMBL1203005)
Show SMILES CCCCN1CCC=C(C1)c1csc(NC)n1
Show InChI InChI=1S/C13H21N3S/c1-3-4-7-16-8-5-6-11(9-16)12-10-17-13(14-2)15-12/h6,10H,3-5,7-9H2,1-2H3,(H,14,15)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (25% inhibition at 10 e-6 M)


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367938
PNG
(CHEMBL1203009)
Show SMILES CCCN1CCCC(C1)c1csc(N)n1
Show InChI InChI=1S/C11H19N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h8-9H,2-7H2,1H3,(H2,12,13)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (15% inhibition at 10 e-6 M)


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367945
PNG
(CHEMBL1203008)
Show SMILES CN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C9H13N3S/c1-12-4-2-3-7(5-12)8-6-13-9(10)11-8/h3,6H,2,4-5H2,1H3,(H2,10,11)
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n/an/a 1.04E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367946
PNG
(CHEMBL1203001)
Show SMILES Nc1nc(cs1)C1=CCCN(CCc2ccccc2)C1
Show InChI InChI=1S/C16H19N3S/c17-16-18-15(12-20-16)14-7-4-9-19(11-14)10-8-13-5-2-1-3-6-13/h1-3,5-7,12H,4,8-11H2,(H2,17,18)
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n/an/a 1.08E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367943
PNG
(CHEMBL1202201)
Show SMILES CCCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C13H21N3S/c1-2-3-4-7-16-8-5-6-11(9-16)12-10-17-13(14)15-12/h6,10H,2-5,7-9H2,1H3,(H2,14,15)
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n/an/a 1.85E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367940
PNG
(CHEMBL1203007)
Show SMILES CCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C12H19N3S/c1-2-3-6-15-7-4-5-10(8-15)11-9-16-12(13)14-11/h5,9H,2-4,6-8H2,1H3,(H2,13,14)
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n/an/a 2.12E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367944
PNG
(CHEMBL1203004)
Show SMILES CCCCCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C15H25N3S/c1-2-3-4-5-6-9-18-10-7-8-13(11-18)14-12-19-15(16)17-14/h8,12H,2-7,9-11H2,1H3,(H2,16,17)
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n/an/a 2.17E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367939
PNG
(CHEMBL1203002)
Show SMILES CC(C)CCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C13H21N3S/c1-10(2)5-7-16-6-3-4-11(8-16)12-9-17-13(14)15-12/h4,9-10H,3,5-8H2,1-2H3,(H2,14,15)
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n/an/a 2.69E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367940
PNG
(CHEMBL1203007)
Show SMILES CCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C12H19N3S/c1-2-3-6-15-7-4-5-10(8-15)11-9-16-12(13)14-11/h5,9H,2-4,6-8H2,1H3,(H2,13,14)
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n/an/a 3.99E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367944
PNG
(CHEMBL1203004)
Show SMILES CCCCCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C15H25N3S/c1-2-3-4-5-6-9-18-10-7-8-13(11-18)14-12-19-15(16)17-14/h8,12H,2-7,9-11H2,1H3,(H2,16,17)
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n/an/a 5.13E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367941
PNG
(CHEMBL1203003)
Show SMILES CCCCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C14H23N3S/c1-2-3-4-5-8-17-9-6-7-12(10-17)13-11-18-14(15)16-13/h7,11H,2-6,8-10H2,1H3,(H2,15,16)
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n/an/a 5.33E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367943
PNG
(CHEMBL1202201)
Show SMILES CCCCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C13H21N3S/c1-2-3-4-7-16-8-5-6-11(9-16)12-10-17-13(14)15-12/h6,10H,2-5,7-9H2,1H3,(H2,14,15)
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n/an/a 6.40E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM81924
PNG
((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Show SMILES CCCN1CCCC(C1)c1cccc(O)c1
Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determined


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367939
PNG
(CHEMBL1203002)
Show SMILES CC(C)CCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C13H21N3S/c1-10(2)5-7-16-6-3-4-11(8-16)12-9-17-13(14)15-12/h4,9-10H,3,5-8H2,1-2H3,(H2,14,15)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranes


Citation and Details
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50010580
PNG
(4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Show SMILES Nc1nc(cs1)C1=CCCN(CC=C)C1
Show InChI InChI=1S/C11H15N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h2,4,8H,1,3,5-7H2,(H2,12,13)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determined


Citation and Details
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50007573
PNG
(4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...)
Show SMILES CCCN1CCC=C(C1)c1csc(N)n1
Show InChI InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h4,8H,2-3,5-7H2,1H3,(H2,12,13)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determined


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%