Affinity Data by PubMed id=1967317

PubMed code 1967317

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22885 (3-[(2S)-1-(1H-imidazol-5-yl)propan-2-yl]-2-(2-{[(5...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonistic activity at histamine H3 receptor in rat cerebral cortex and is represented as Ki				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM85411 (GT 2174) Show SMILES O=C(CCCC1CCCCC1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against histamine H3 receptor and is represented as -log Ki.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22886 (3-[(2R)-1-(1H-imidazol-5-yl)propan-2-yl]-2-(2-{[(5...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonistic activity at histamine H3 receptor in rat cerebral cortex and is represented as Ki.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406098 (CHEMBL12494) Show SMILES O=C(CCCc1ccccc1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against Histamine H3 receptor and represented as KB.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406100 (CHEMBL12459) Show SMILES O=C(CCCCc1ccccc1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against Histamine H3 receptor and represented as KB.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406095 (CHEMBL275090) Show SMILES C(CCc1ccccc1)CNCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against histamine H3 receptor and is represented as -log Ki.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406101 (CHEMBL12550) Show SMILES O=C(CCc1ccccc1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against Histamine H3 receptor and represented as KB.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406099 (CHEMBL416338) Show SMILES O=C(CCCc1cnc[nH]1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against histamine H3 receptor and is represented as -log Ki.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406097 (CHEMBL12551) Show SMILES O=C(CCC(c1ccccc1)c1ccccc1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against histamine H3 receptor and is represented as -log Ki.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406093 (CHEMBL276903) Show SMILES O=C(CCCc1ccccn1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against Histamine H3 receptor and represented as KB.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50406096 (CHEMBL12025) Show SMILES O=C(Cc1ccccc1)NCCc1cnc[nH]1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Evaluated for antagonist activity against Histamine H3 receptor and represented as KB.				J Med Chem 33: 4-11 (1990) Article DOI: 10.1021/jm00163a001 BindingDB Entry DOI: 10.7270/Q2GB230D
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%