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PubMed code 1967651

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50010589
PNG
(6,7-Dihydro-5H-indeno[5,6-d][1,3]dioxol-6-ylamine ...)
Show SMILES NC1Cc2cc3OCOc3cc2C1
Show InChI InChI=1S/C10H11NO2/c11-8-1-6-3-9-10(13-5-12-9)4-7(6)2-8/h3-4,8H,1-2,5,11H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 0.104n/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity was determined towards serotonin uptake site in presence of [3H]-paroxetine radioligand in rat brain cortical homogenate


Citation and Details
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50010589
PNG
(6,7-Dihydro-5H-indeno[5,6-d][1,3]dioxol-6-ylamine ...)
Show SMILES NC1Cc2cc3OCOc3cc2C1
Show InChI InChI=1S/C10H11NO2/c11-8-1-6-3-9-10(13-5-12-9)4-7(6)2-8/h3-4,8H,1-2,5,11H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 0.127n/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity was determined towards serotonin uptake site in presence of [3H]-paroxetine radioligand in rat hippocampal homogenate


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%