Affinity Data by PubMed id=1967653

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydroorotase (Homo sapiens)	BDBM50010599 (6-Mercaptomethyl-2-oxo-2,3,4,5-tetrahydro-pyrimidi...) Show SMILES OC(=O)C1CC(NC(=O)N1)C=S Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Mayo Clinic & Foundation Curated by ChEMBL					Assay Description Inhibitory activity against Dihydroorotase (DHO) at pH 7.4 and 8.5				J Med Chem 33: 819-23 (1990) Article DOI: 10.1021/jm00164a055 BindingDB Entry DOI: 10.7270/Q2ZC81VR
Mayo Clinic & Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydroorotase (Homo sapiens)	BDBM50010600 (CHEMBL168878 \| Ethyl-3-borono-2-(carbamylamino)pro...) Show SMILES CCOC(=O)C(CB(O)O)NC(N)=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Mayo Clinic & Foundation Curated by ChEMBL					Assay Description Inhibitory activity against Dihydroorotase (DHO) at pH 6.0				J Med Chem 33: 819-23 (1990) Article DOI: 10.1021/jm00164a055 BindingDB Entry DOI: 10.7270/Q2ZC81VR
Mayo Clinic & Foundation Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%