BindingDB logo
myBDB logout

PubMed code 1967653

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotase


(Homo sapiens)
BDBM50010599
PNG
(6-Mercaptomethyl-2-oxo-2,3,4,5-tetrahydro-pyrimidi...)
Show SMILES OC(=O)C1CC(NC(=O)N1)C=S
Show InChI InChI=1S/C6H8N2O3S/c9-5(10)4-1-3(2-12)7-6(11)8-4/h2-4H,1H2,(H,9,10)(H2,7,8,11)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
140n/an/an/an/an/an/an/an/a



Mayo Clinic & Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity against Dihydroorotase (DHO) at pH 7.4 and 8.5


Citation and Details
More data for this
Ligand-Target Pair
Dihydroorotase


(Homo sapiens)
BDBM50010600
PNG
(CHEMBL168878 | Ethyl-3-borono-2-(carbamylamino)pro...)
Show SMILES CCOC(=O)C(CB(O)O)NC(N)=O
Show InChI InChI=1S/C6H13BN2O5/c1-2-14-5(10)4(3-7(12)13)9-6(8)11/h4,12-13H,2-3H2,1H3,(H3,8,9,11)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
5.07E+3n/an/an/an/an/an/an/an/a



Mayo Clinic & Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity against Dihydroorotase (DHO) at pH 6.0


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%