Affinity Data by PubMed id=1968512

PubMed code 1968512

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010621 (6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-t...) Show SMILES CCCN(CCc1ccsc1)C1CCc2c(O)cccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010621 (6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-t...) Show SMILES CCCN(CCc1ccsc1)C1CCc2c(O)cccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010613 (3-(Octahydro-indolizin-8-yl)-phenol \| CHEMBL7850) Show SMILES Oc1cccc(c1)[C@H]1CCCN2CCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010616 ((+)-3-(Octahydro-indolizin-8-yl)-phenol \| (-)-3-(O...) Show SMILES Oc1cccc(c1)C1CCCN2CCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010620 (3-(Octahydro-indolizin-8-yl)-phenol \| CHEMBL8074) Show SMILES Oc1cccc(c1)[C@@H]1CCCN2CCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010615 (3-(3,6,7,8,9,9a-Hexahydro-4H-quinolizin-1-yl)-phen...) Show SMILES Oc1cccc(c1)C1=CCCN2CCCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010614 (3-(Octahydro-quinolizin-1-yl)-phenol \| CHEMBL7381 ...) Show SMILES Oc1cccc(c1)C1CCCN2CCCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010616 ((+)-3-(Octahydro-indolizin-8-yl)-phenol \| (-)-3-(O...) Show SMILES Oc1cccc(c1)C1CCCN2CCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010613 (3-(Octahydro-indolizin-8-yl)-phenol \| CHEMBL7850) Show SMILES Oc1cccc(c1)[C@H]1CCCN2CCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010615 (3-(3,6,7,8,9,9a-Hexahydro-4H-quinolizin-1-yl)-phen...) Show SMILES Oc1cccc(c1)C1=CCCN2CCCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010620 (3-(Octahydro-indolizin-8-yl)-phenol \| CHEMBL8074) Show SMILES Oc1cccc(c1)[C@@H]1CCCN2CCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50452756 (CHEMBL2051756) Show SMILES Oc1cccc(c1)C1CCC2CCCCN2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010614 (3-(Octahydro-quinolizin-1-yl)-phenol \| CHEMBL7381 ...) Show SMILES Oc1cccc(c1)C1CCCN2CCCCC12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50452756 (CHEMBL2051756) Show SMILES Oc1cccc(c1)C1CCC2CCCCN2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) Article DOI: 10.1021/jm00165a020 BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%